Successful Use of a Midline Catheter for Leukapheresis in Patients Undergoing Collection for Immune Effector Cell Therapy, Donor Lymphocyte Infusion, and Hematopoietic Progenitor Cell Collection

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Main Authors: Rajat Bansal, Anthony Wiedel, Riley Hastings, Fred Boutz, Haitham Abdelhakim, Nausheen Ahmed, Muhammad Umair Mushtaq, Joseph McGuirk, Sunil Abhyankar
Format: Artículo Open Access
Published: Wiley 2025
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author Rajat Bansal
Anthony Wiedel
Riley Hastings
Fred Boutz
Haitham Abdelhakim
Nausheen Ahmed
Muhammad Umair Mushtaq
Joseph McGuirk
Sunil Abhyankar
author_facet Rajat Bansal
Anthony Wiedel
Riley Hastings
Fred Boutz
Haitham Abdelhakim
Nausheen Ahmed
Muhammad Umair Mushtaq
Joseph McGuirk
Sunil Abhyankar
Rajat Bansal
Anthony Wiedel
Riley Hastings
Fred Boutz
Haitham Abdelhakim
Nausheen Ahmed
Muhammad Umair Mushtaq
Joseph McGuirk
Sunil Abhyankar
collection Wiley Open Access
contents Successful Use of a Midline Catheter for Leukapheresis in Patients Undergoing Collection for Immune Effector Cell Therapy, Donor Lymphocyte Infusion, and Hematopoietic Progenitor Cell Collection Rajat Bansal Anthony Wiedel Riley Hastings Fred Boutz Haitham Abdelhakim Nausheen Ahmed Muhammad Umair Mushtaq Joseph McGuirk Sunil Abhyankar Journal of Clinical Apheresis ABSTRACTApheresis is essential to conducting hematopoietic cell transplantation and genetically engineered cellular therapy procedures. Many patients and donors require central venous catheter (CVC) access for apheresis due to lack of adequate peripheral venous access. CVC placement has risks of associated complications and requires additional institutional resources and expertise. We present a single institutional experience with 78 patients, who underwent a total of 87 apheresis procedures after placement of a midline catheter. This included 49 individuals who collected cells for immune effector cell therapy. Apheresis through midline catheter was successful in 81 out of 87 procedures. There were no midline catheter associated thromboses or infections. Six patients required placement of a backup CVC and were able to undergo apheresis without delay. Our experience shows that use of midline catheter for apheresis is feasible and generalizable to most populations requiring cellular therapy, with the potential to decrease utilization of limited healthcare resources. 10.1002/jca.70004 http://onlinelibrary.wiley.com/termsAndConditions#vor
doi_str_mv 10.1002/jca.70004
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spellingShingle Successful Use of a Midline Catheter for Leukapheresis in Patients Undergoing Collection for Immune Effector Cell Therapy, Donor Lymphocyte Infusion, and Hematopoietic Progenitor Cell Collection
Rajat Bansal
Anthony Wiedel
Riley Hastings
Fred Boutz
Haitham Abdelhakim
Nausheen Ahmed
Muhammad Umair Mushtaq
Joseph McGuirk
Sunil Abhyankar
Journal of Clinical Apheresis
Successful Use of a Midline Catheter for Leukapheresis in Patients Undergoing Collection for Immune Effector Cell Therapy, Donor Lymphocyte Infusion, and Hematopoietic Progenitor Cell Collection Rajat Bansal Anthony Wiedel Riley Hastings Fred Boutz Haitham Abdelhakim Nausheen Ahmed Muhammad Umair Mushtaq Joseph McGuirk Sunil Abhyankar Journal of Clinical Apheresis ABSTRACTApheresis is essential to conducting hematopoietic cell transplantation and genetically engineered cellular therapy procedures. Many patients and donors require central venous catheter (CVC) access for apheresis due to lack of adequate peripheral venous access. CVC placement has risks of associated complications and requires additional institutional resources and expertise. We present a single institutional experience with 78 patients, who underwent a total of 87 apheresis procedures after placement of a midline catheter. This included 49 individuals who collected cells for immune effector cell therapy. Apheresis through midline catheter was successful in 81 out of 87 procedures. There were no midline catheter associated thromboses or infections. Six patients required placement of a backup CVC and were able to undergo apheresis without delay. Our experience shows that use of midline catheter for apheresis is feasible and generalizable to most populations requiring cellular therapy, with the potential to decrease utilization of limited healthcare resources. 10.1002/jca.70004 http://onlinelibrary.wiley.com/termsAndConditions#vor
title Successful Use of a Midline Catheter for Leukapheresis in Patients Undergoing Collection for Immune Effector Cell Therapy, Donor Lymphocyte Infusion, and Hematopoietic Progenitor Cell Collection
topic Journal of Clinical Apheresis
url https://onlinelibrary.wiley.com/doi/10.1002/jca.70004