Transient Wavy Collection Trend in Hematopoietic Stem Cell Apheresis: A Rare and Underreported Occurrence

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Autori principali: Dibyajyoti Sahoo, Aparna Krishna, Abhishekh Basavarajegowda
Natura: Artículo Open Access
Pubblicazione: Wiley 2025
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author Dibyajyoti Sahoo
Aparna Krishna
Abhishekh Basavarajegowda
author_facet Dibyajyoti Sahoo
Aparna Krishna
Abhishekh Basavarajegowda
Dibyajyoti Sahoo
Aparna Krishna
Abhishekh Basavarajegowda
collection Wiley Open Access
contents Transient Wavy Collection Trend in Hematopoietic Stem Cell Apheresis: A Rare and Underreported Occurrence Dibyajyoti Sahoo Aparna Krishna Abhishekh Basavarajegowda Journal of Clinical Apheresis ABSTRACT Hematopoietic stem cell transplantation is a key therapeutic approach for various malignancies in recent years. Peripheral blood hematopoietic stem cells are typically collected using the apheresis technique following mobilization. However, during the collection process various challenges may arise. Here we report a rare occurrence during stem cell collection, where the collection trend graph exhibited a persistent wavy pattern throughout most of the procedure. The patient was found to be dehydrated on examination and was hydrated with normal saline IV, after which the wavy pattern resolved. The cells started collecting from the same collection preference that was set by the operator and the green diamonds, which depict cells aligned in a straight line. This is the first documented report of a wavy interface pattern during stem cell collection. This report contributes to the existing literature and may provide valuable insights for troubleshooting similar occurrences in future cases. 10.1002/jca.70040 http://onlinelibrary.wiley.com/termsAndConditions#vor
doi_str_mv 10.1002/jca.70040
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id wiley_oa_10_1002_jca_70040
institution Wiley Open Access
license_str_mv http://onlinelibrary.wiley.com/termsAndConditions#vor
publishDate 2025
publisher Wiley
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spellingShingle Transient Wavy Collection Trend in Hematopoietic Stem Cell Apheresis: A Rare and Underreported Occurrence
Dibyajyoti Sahoo
Aparna Krishna
Abhishekh Basavarajegowda
Journal of Clinical Apheresis
Transient Wavy Collection Trend in Hematopoietic Stem Cell Apheresis: A Rare and Underreported Occurrence Dibyajyoti Sahoo Aparna Krishna Abhishekh Basavarajegowda Journal of Clinical Apheresis ABSTRACT Hematopoietic stem cell transplantation is a key therapeutic approach for various malignancies in recent years. Peripheral blood hematopoietic stem cells are typically collected using the apheresis technique following mobilization. However, during the collection process various challenges may arise. Here we report a rare occurrence during stem cell collection, where the collection trend graph exhibited a persistent wavy pattern throughout most of the procedure. The patient was found to be dehydrated on examination and was hydrated with normal saline IV, after which the wavy pattern resolved. The cells started collecting from the same collection preference that was set by the operator and the green diamonds, which depict cells aligned in a straight line. This is the first documented report of a wavy interface pattern during stem cell collection. This report contributes to the existing literature and may provide valuable insights for troubleshooting similar occurrences in future cases. 10.1002/jca.70040 http://onlinelibrary.wiley.com/termsAndConditions#vor
title Transient Wavy Collection Trend in Hematopoietic Stem Cell Apheresis: A Rare and Underreported Occurrence
topic Journal of Clinical Apheresis
url https://onlinelibrary.wiley.com/doi/10.1002/jca.70040