Developing a Protocol for Therapeutic Plasma Exchange in Tandem With Continuous Renal Replacement Therapy (CRRT) and ExtraCorporeal Membrane Oxygenation (ECMO) in Pediatric Patients

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Auteurs principaux: Cyril Jacquot, Maria Di Mola, Reuben Jacob, Gagan Mathur, Cheryl Pacheco, Angelica Vivero, Zachary Corey, Ileana Lopez‐Plaza, Kyle Annen
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Publié: Wiley 2025
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author Cyril Jacquot
Maria Di Mola
Reuben Jacob
Gagan Mathur
Cheryl Pacheco
Angelica Vivero
Zachary Corey
Ileana Lopez‐Plaza
Kyle Annen
author_facet Cyril Jacquot
Maria Di Mola
Reuben Jacob
Gagan Mathur
Cheryl Pacheco
Angelica Vivero
Zachary Corey
Ileana Lopez‐Plaza
Kyle Annen
Cyril Jacquot
Maria Di Mola
Reuben Jacob
Gagan Mathur
Cheryl Pacheco
Angelica Vivero
Zachary Corey
Ileana Lopez‐Plaza
Kyle Annen
collection Wiley Open Access
contents Developing a Protocol for Therapeutic Plasma Exchange in Tandem With Continuous Renal Replacement Therapy (CRRT) and ExtraCorporeal Membrane Oxygenation (ECMO) in Pediatric Patients Cyril Jacquot Maria Di Mola Reuben Jacob Gagan Mathur Cheryl Pacheco Angelica Vivero Zachary Corey Ileana Lopez‐Plaza Kyle Annen Journal of Clinical Apheresis ABSTRACTTherapeutic plasma exchange (TPE) in pediatric patients presents many challenges, including management of a large extracorporeal volume (ECV) and calcium replacement for patients who may not be able to express signs of hypocalcemia or other associated adverse events with a large ECV. Pediatric patients who are critically ill on continuous renal replacement therapy (CRRT) and/or extracorporeal membrane oxygenation (ECMO) may have indications for TPE, such as sepsis or liver failure anticipating transplant. It may be difficult or clinically detrimental to take the patient off the CRRT or ECMO circuit to perform TPE. Connecting the TPE device into the preexisting circuit is feasible with the understanding of the principles of the circuit flow set up and monitoring to mitigate adverse events. Effective communication among clinical teams managing distinct extracorporeal circuits is critical to ensuring coordinated patient care. 10.1002/jca.70051 http://onlinelibrary.wiley.com/termsAndConditions#vor
doi_str_mv 10.1002/jca.70051
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spellingShingle Developing a Protocol for Therapeutic Plasma Exchange in Tandem With Continuous Renal Replacement Therapy (CRRT) and ExtraCorporeal Membrane Oxygenation (ECMO) in Pediatric Patients
Cyril Jacquot
Maria Di Mola
Reuben Jacob
Gagan Mathur
Cheryl Pacheco
Angelica Vivero
Zachary Corey
Ileana Lopez‐Plaza
Kyle Annen
Journal of Clinical Apheresis
Developing a Protocol for Therapeutic Plasma Exchange in Tandem With Continuous Renal Replacement Therapy (CRRT) and ExtraCorporeal Membrane Oxygenation (ECMO) in Pediatric Patients Cyril Jacquot Maria Di Mola Reuben Jacob Gagan Mathur Cheryl Pacheco Angelica Vivero Zachary Corey Ileana Lopez‐Plaza Kyle Annen Journal of Clinical Apheresis ABSTRACTTherapeutic plasma exchange (TPE) in pediatric patients presents many challenges, including management of a large extracorporeal volume (ECV) and calcium replacement for patients who may not be able to express signs of hypocalcemia or other associated adverse events with a large ECV. Pediatric patients who are critically ill on continuous renal replacement therapy (CRRT) and/or extracorporeal membrane oxygenation (ECMO) may have indications for TPE, such as sepsis or liver failure anticipating transplant. It may be difficult or clinically detrimental to take the patient off the CRRT or ECMO circuit to perform TPE. Connecting the TPE device into the preexisting circuit is feasible with the understanding of the principles of the circuit flow set up and monitoring to mitigate adverse events. Effective communication among clinical teams managing distinct extracorporeal circuits is critical to ensuring coordinated patient care. 10.1002/jca.70051 http://onlinelibrary.wiley.com/termsAndConditions#vor
title Developing a Protocol for Therapeutic Plasma Exchange in Tandem With Continuous Renal Replacement Therapy (CRRT) and ExtraCorporeal Membrane Oxygenation (ECMO) in Pediatric Patients
topic Journal of Clinical Apheresis
url https://onlinelibrary.wiley.com/doi/10.1002/jca.70051