Unusual Icteric Discoloration of Single Donor Platelets in Platelet Additive Solution With Container Staining: A Rare Observation
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2025
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| author | Suvetha Rajendran Harsha Unni Mohandoss Murugesan Anju R. Kurup Sangeetha K. Nayanar |
| author_facet | Suvetha Rajendran Harsha Unni Mohandoss Murugesan Anju R. Kurup Sangeetha K. Nayanar Suvetha Rajendran Harsha Unni Mohandoss Murugesan Anju R. Kurup Sangeetha K. Nayanar |
| collection | Wiley Open Access |
| contents | Unusual Icteric Discoloration of Single Donor Platelets in Platelet Additive Solution With Container Staining: A Rare Observation Suvetha Rajendran Harsha Unni Mohandoss Murugesan Anju R. Kurup Sangeetha K. Nayanar Journal of Clinical Apheresis ABSTRACT This report describes an unusual case of an apheresis platelet (AP) unit in platelet additive solution (PAS) exhibiting marked icteric discoloration and bag staining, despite sterile cultures and initially preserved platelet morphology. Donor evaluation revealed mild unconjugated hyperbilirubinemia, implicating donor‐derived pigments as the source of discoloration. By Day 5, reduced platelet function was observed. This case underscores that icteric appearance in PAS‐suspended platelets, though rare, may signal donor‐related pigment transfer and warrants reevaluation of current visual inspection and acceptance for blood components. 10.1002/jca.70086 http://onlinelibrary.wiley.com/termsAndConditions#vor |
| doi_str_mv | 10.1002/jca.70086 |
| format | Artículo Open Access |
| id | wiley_oa_10_1002_jca_70086 |
| institution | Wiley Open Access |
| license_str_mv | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| publishDate | 2025 |
| publisher | Wiley |
| record_format | wiley_oa |
| spellingShingle | Unusual Icteric Discoloration of Single Donor Platelets in Platelet Additive Solution With Container Staining: A Rare Observation Suvetha Rajendran Harsha Unni Mohandoss Murugesan Anju R. Kurup Sangeetha K. Nayanar Journal of Clinical Apheresis Unusual Icteric Discoloration of Single Donor Platelets in Platelet Additive Solution With Container Staining: A Rare Observation Suvetha Rajendran Harsha Unni Mohandoss Murugesan Anju R. Kurup Sangeetha K. Nayanar Journal of Clinical Apheresis ABSTRACT This report describes an unusual case of an apheresis platelet (AP) unit in platelet additive solution (PAS) exhibiting marked icteric discoloration and bag staining, despite sterile cultures and initially preserved platelet morphology. Donor evaluation revealed mild unconjugated hyperbilirubinemia, implicating donor‐derived pigments as the source of discoloration. By Day 5, reduced platelet function was observed. This case underscores that icteric appearance in PAS‐suspended platelets, though rare, may signal donor‐related pigment transfer and warrants reevaluation of current visual inspection and acceptance for blood components. 10.1002/jca.70086 http://onlinelibrary.wiley.com/termsAndConditions#vor |
| title | Unusual Icteric Discoloration of Single Donor Platelets in Platelet Additive Solution With Container Staining: A Rare Observation |
| topic | Journal of Clinical Apheresis |
| url | https://onlinelibrary.wiley.com/doi/10.1002/jca.70086 |