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Main Authors: Xiankun Sun, Xu Li, Fang Wang, Zhiwen Chen, Ling Zhang
Format: Artículo Open Access
Published: Wiley 2026
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Online Access:https://onlinelibrary.wiley.com/doi/10.1002/jca.70121
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author Xiankun Sun
Xu Li
Fang Wang
Zhiwen Chen
Ling Zhang
author_facet Xiankun Sun
Xu Li
Fang Wang
Zhiwen Chen
Ling Zhang
Xiankun Sun
Xu Li
Fang Wang
Zhiwen Chen
Ling Zhang
collection Wiley Open Access
contents Double Plasma Molecular Adsorption System Plus Sequential Half‐Dose Plasmapheresis in Tandem With Continuous Renal Replacement Therapy: A Case Report Xiankun Sun Xu Li Fang Wang Zhiwen Chen Ling Zhang Journal of Clinical Apheresis ABSTRACT A 48‐year‐old male patient was diagnosed with critical acute pancreatitis, renal dysfunction and liver dysfunction. Because of the presence of multiorgan dysfunction, continuous renal replacement therapy (CRRT) was required on the first day of the patient's admission to the ICU in order to help stabilize the patient's internal environment. Meanwhile, the patient also received a total of five double plasma molecular adsorption system plus sequential half‐dose plasmapheresis (DPMAS‐PE) treatments, of which the first, fourth, and fifth DPMAS‐PE treatments were chosen to be administered concurrently with CRRT. This report is to clarify how four CRRT machines using three parallel modalities successfully completed DPMAS‐PE in tandem with CRRT (DPMAS‐PE‐CRRT). Furthermore, DPMAS‐PE‐CRRT showed similar effectiveness in removing total bilirubin and total bile acid when compared to nonparallel CRRT. During the parallel therapy, there were no serious adverse reactions. To validate this case, more clinical trials are needed. 10.1002/jca.70121 http://onlinelibrary.wiley.com/termsAndConditions#vor
doi_str_mv 10.1002/jca.70121
format Artículo Open Access
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institution Wiley Open Access
license_str_mv http://onlinelibrary.wiley.com/termsAndConditions#vor
publishDate 2026
publisher Wiley
record_format wiley_oa
spellingShingle Double Plasma Molecular Adsorption System Plus Sequential Half‐Dose Plasmapheresis in Tandem With Continuous Renal Replacement Therapy: A Case Report
Xiankun Sun
Xu Li
Fang Wang
Zhiwen Chen
Ling Zhang
Journal of Clinical Apheresis
Double Plasma Molecular Adsorption System Plus Sequential Half‐Dose Plasmapheresis in Tandem With Continuous Renal Replacement Therapy: A Case Report Xiankun Sun Xu Li Fang Wang Zhiwen Chen Ling Zhang Journal of Clinical Apheresis ABSTRACT A 48‐year‐old male patient was diagnosed with critical acute pancreatitis, renal dysfunction and liver dysfunction. Because of the presence of multiorgan dysfunction, continuous renal replacement therapy (CRRT) was required on the first day of the patient's admission to the ICU in order to help stabilize the patient's internal environment. Meanwhile, the patient also received a total of five double plasma molecular adsorption system plus sequential half‐dose plasmapheresis (DPMAS‐PE) treatments, of which the first, fourth, and fifth DPMAS‐PE treatments were chosen to be administered concurrently with CRRT. This report is to clarify how four CRRT machines using three parallel modalities successfully completed DPMAS‐PE in tandem with CRRT (DPMAS‐PE‐CRRT). Furthermore, DPMAS‐PE‐CRRT showed similar effectiveness in removing total bilirubin and total bile acid when compared to nonparallel CRRT. During the parallel therapy, there were no serious adverse reactions. To validate this case, more clinical trials are needed. 10.1002/jca.70121 http://onlinelibrary.wiley.com/termsAndConditions#vor
title Double Plasma Molecular Adsorption System Plus Sequential Half‐Dose Plasmapheresis in Tandem With Continuous Renal Replacement Therapy: A Case Report
topic Journal of Clinical Apheresis
url https://onlinelibrary.wiley.com/doi/10.1002/jca.70121