Hypopharyngeal Amyloidosis: A Rare Cause of Dysphagia

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Hauptverfasser: Jane B. Buell, Ari D. Schuman, Julina Ongkasuwan, Adam Szymanowski
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Veröffentlicht: Wiley 2025
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author Jane B. Buell
Ari D. Schuman
Julina Ongkasuwan
Adam Szymanowski
author_facet Jane B. Buell
Ari D. Schuman
Julina Ongkasuwan
Adam Szymanowski
Jane B. Buell
Ari D. Schuman
Julina Ongkasuwan
Adam Szymanowski
collection Wiley Open Access
contents Hypopharyngeal Amyloidosis: A Rare Cause of Dysphagia Jane B. Buell Ari D. Schuman Julina Ongkasuwan Adam Szymanowski The Laryngoscope AbstractAmyloidosis localized to the head and neck most commonly affects the laryngo‐tracheobronchial tree or tongue. It rarely affects the hypopharynx, with only 3 cases reported in literature. All of these cases describe females presenting with hypopharyngeal amyloid masses and associated multiple myeloma or monoclonal gammopathy of undetermined significance. They were treated with chemotherapy and CO2 laser, respectively. In comparison, our case identifies a 69‐year‐old female, with a history of MALT lymphoma but no concurrent malignancy. She initially presented with dysphagia and was diagnosed with hypopharyngeal amyloidosis. After 532 nm potassium titanyl phosphate laser treatment, she ultimately felt improvement in her dysphagia. Laryngoscope, 135:2086–2088, 2025 10.1002/lary.32021 http://onlinelibrary.wiley.com/termsAndConditions#vor
doi_str_mv 10.1002/lary.32021
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institution Wiley Open Access
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publisher Wiley
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spellingShingle Hypopharyngeal Amyloidosis: A Rare Cause of Dysphagia
Jane B. Buell
Ari D. Schuman
Julina Ongkasuwan
Adam Szymanowski
The Laryngoscope
Hypopharyngeal Amyloidosis: A Rare Cause of Dysphagia Jane B. Buell Ari D. Schuman Julina Ongkasuwan Adam Szymanowski The Laryngoscope AbstractAmyloidosis localized to the head and neck most commonly affects the laryngo‐tracheobronchial tree or tongue. It rarely affects the hypopharynx, with only 3 cases reported in literature. All of these cases describe females presenting with hypopharyngeal amyloid masses and associated multiple myeloma or monoclonal gammopathy of undetermined significance. They were treated with chemotherapy and CO2 laser, respectively. In comparison, our case identifies a 69‐year‐old female, with a history of MALT lymphoma but no concurrent malignancy. She initially presented with dysphagia and was diagnosed with hypopharyngeal amyloidosis. After 532 nm potassium titanyl phosphate laser treatment, she ultimately felt improvement in her dysphagia. Laryngoscope, 135:2086–2088, 2025 10.1002/lary.32021 http://onlinelibrary.wiley.com/termsAndConditions#vor
title Hypopharyngeal Amyloidosis: A Rare Cause of Dysphagia
topic The Laryngoscope
url https://onlinelibrary.wiley.com/doi/10.1002/lary.32021