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| Main Authors: | , , |
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| Format: | Artículo Open Access |
| Published: |
Wiley
2024
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| Online Access: | https://onlinelibrary.wiley.com/doi/10.1002/mco2.607 |
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| _version_ | 1867020512428818432 |
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| author | Lin‐Zhu Zhang Xu He Hai‐Dong Zhu |
| author_facet | Lin‐Zhu Zhang Xu He Hai‐Dong Zhu Lin‐Zhu Zhang Xu He Hai‐Dong Zhu |
| collection | Wiley Open Access |
| contents | Targeting CD300ld to normalize the tumor microenvironment: an emerging insight in cancer immunotherapy Lin‐Zhu Zhang Xu He Hai‐Dong Zhu MedComm AbstractIn a recent Nature elegant study, Wang et al. identified CD300ld, a novel functionally highly conserved tumor immunosuppressive receptor, highly expressed specifically on polymorphonuclear myeloid‐derived suppressor cells (PMN‐MDSCs), as well as a key receptor in the regulation of recruitment and immunosuppressive function of PMN‐MDSCs. Targeting CD300ld could remodel the tumor immune microenvironment, resulting in a broad‐spectrum anti‐tumor effect. 10.1002/mco2.607 http://creativecommons.org/licenses/by/4.0/ |
| doi_str_mv | 10.1002/mco2.607 |
| format | Artículo Open Access |
| id | wiley_oa_10_1002_mco2_607 |
| institution | Wiley Open Access |
| license_str_mv | http://creativecommons.org/licenses/by/4.0/ |
| publishDate | 2024 |
| publisher | Wiley |
| record_format | wiley_oa |
| spellingShingle | Targeting CD300ld to normalize the tumor microenvironment: an emerging insight in cancer immunotherapy Lin‐Zhu Zhang Xu He Hai‐Dong Zhu MedComm Targeting CD300ld to normalize the tumor microenvironment: an emerging insight in cancer immunotherapy Lin‐Zhu Zhang Xu He Hai‐Dong Zhu MedComm AbstractIn a recent Nature elegant study, Wang et al. identified CD300ld, a novel functionally highly conserved tumor immunosuppressive receptor, highly expressed specifically on polymorphonuclear myeloid‐derived suppressor cells (PMN‐MDSCs), as well as a key receptor in the regulation of recruitment and immunosuppressive function of PMN‐MDSCs. Targeting CD300ld could remodel the tumor immune microenvironment, resulting in a broad‐spectrum anti‐tumor effect. 10.1002/mco2.607 http://creativecommons.org/licenses/by/4.0/ |
| title | Targeting CD300ld to normalize the tumor microenvironment: an emerging insight in cancer immunotherapy |
| topic | MedComm |
| url | https://onlinelibrary.wiley.com/doi/10.1002/mco2.607 |