Orofacial Drinking Tremor: A Case Series and Literature Review

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Autori principali: Daniele Birreci, Luca Angelini, Simone Aloisio, Anna S. Grandolfo, Sara Cirinei, Adriana Martini, Martina De Riggi, Matteo Bologna
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Pubblicazione: Wiley 2026
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author Daniele Birreci
Luca Angelini
Simone Aloisio
Anna S. Grandolfo
Sara Cirinei
Adriana Martini
Martina De Riggi
Matteo Bologna
author_facet Daniele Birreci
Luca Angelini
Simone Aloisio
Anna S. Grandolfo
Sara Cirinei
Adriana Martini
Martina De Riggi
Matteo Bologna
Daniele Birreci
Luca Angelini
Simone Aloisio
Anna S. Grandolfo
Sara Cirinei
Adriana Martini
Martina De Riggi
Matteo Bologna
collection Wiley Open Access
contents Orofacial Drinking Tremor: A Case Series and Literature Review Daniele Birreci Luca Angelini Simone Aloisio Anna S. Grandolfo Sara Cirinei Adriana Martini Martina De Riggi Matteo Bologna Movement Disorders Clinical Practice Abstract Background Task‐specific orofacial tremor is a rare condition in which rhythmic oscillations of orofacial muscles occur during specific actions. Drinking tremor represents a recurrent pattern in isolated reports, although its phenomenology and underlying mechanisms remain incompletely defined. Cases We report three cases of orofacial drinking tremor, each showing a different pattern. Differences involved the distribution of orofacial muscle activity and the presence of additional signs, including tremor in other body regions or subtle dystonic postures. Variability in task dependence, posture sensitivity, and sensory modulation contributed to the heterogeneity of these presentations. Literature Review Published reports describe a spectrum of orofacial drinking tremors, ranging from strictly task‐specific patterns to mixed task‐ and position‐dependent presentations. Some patients exhibit subtle dystonic features, whereas others show no clear additional neurological signs. Electrophysiology typically demonstrates regular 5–8 Hz rhythmic discharges in the orofacial muscles. Systemic pharmacological therapies offer limited benefit, whereas botulinum toxin remains the most effective option. Conclusions Current evidence suggests that orofacial drinking tremor does not represent a single clinical entity. An approach integrating detailed phenomenological characterization with plausible pathophysiological mechanisms may improve diagnostic interpretation and guide individualized management strategies. 10.1002/mdc3.70621 http://creativecommons.org/licenses/by/4.0/
doi_str_mv 10.1002/mdc3.70621
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spellingShingle Orofacial Drinking Tremor: A Case Series and Literature Review
Daniele Birreci
Luca Angelini
Simone Aloisio
Anna S. Grandolfo
Sara Cirinei
Adriana Martini
Martina De Riggi
Matteo Bologna
Movement Disorders Clinical Practice
Orofacial Drinking Tremor: A Case Series and Literature Review Daniele Birreci Luca Angelini Simone Aloisio Anna S. Grandolfo Sara Cirinei Adriana Martini Martina De Riggi Matteo Bologna Movement Disorders Clinical Practice Abstract Background Task‐specific orofacial tremor is a rare condition in which rhythmic oscillations of orofacial muscles occur during specific actions. Drinking tremor represents a recurrent pattern in isolated reports, although its phenomenology and underlying mechanisms remain incompletely defined. Cases We report three cases of orofacial drinking tremor, each showing a different pattern. Differences involved the distribution of orofacial muscle activity and the presence of additional signs, including tremor in other body regions or subtle dystonic postures. Variability in task dependence, posture sensitivity, and sensory modulation contributed to the heterogeneity of these presentations. Literature Review Published reports describe a spectrum of orofacial drinking tremors, ranging from strictly task‐specific patterns to mixed task‐ and position‐dependent presentations. Some patients exhibit subtle dystonic features, whereas others show no clear additional neurological signs. Electrophysiology typically demonstrates regular 5–8 Hz rhythmic discharges in the orofacial muscles. Systemic pharmacological therapies offer limited benefit, whereas botulinum toxin remains the most effective option. Conclusions Current evidence suggests that orofacial drinking tremor does not represent a single clinical entity. An approach integrating detailed phenomenological characterization with plausible pathophysiological mechanisms may improve diagnostic interpretation and guide individualized management strategies. 10.1002/mdc3.70621 http://creativecommons.org/licenses/by/4.0/
title Orofacial Drinking Tremor: A Case Series and Literature Review
topic Movement Disorders Clinical Practice
url https://movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mdc3.70621