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Autori principali: Neil Thivalapill, Todd M. Jenkins, Thomas H. Inge, Changchun Xie, Anita P. Courcoulas, Carroll M. Harmon, Michael A. Helmrath, Stephanie Sisley, Marc P. Michalsky, Justin R. Ryder
Natura: Artículo Open Access
Pubblicazione: Wiley 2025
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Accesso online:https://onlinelibrary.wiley.com/doi/10.1002/oby.24285
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  • Functional mobility and pain are improved for 6 years after adolescent bariatric surgery Neil Thivalapill Todd M. Jenkins Thomas H. Inge Changchun Xie Anita P. Courcoulas Carroll M. Harmon Michael A. Helmrath Stephanie Sisley Marc P. Michalsky Justin R. Ryder Obesity AbstractObjectiveThe long‐term durability of improvements in functional mobility and musculoskeletal pain for adolescents after metabolic and bariatric surgery (MBS) is unknown.MethodsWe used the Teen‐Longitudinal Assessment of Bariatric Surgery (Teen‐LABS) study to determine the change in mobility and pain among adolescents who underwent MBS. From standardized 400‐m walk tests, we analyzed walk time, heart rate (HR) parameters, and musculoskeletal pain.ResultsThe mean walk time improved from 383 s (95% CI: 368–399) prior to surgery to 351 s (95% CI: 330–372) by 6 years. The mean resting HR was 90 beats per minute (bpm; 95% CI: 87–93) preoperatively and decreased to 80 bpm (95% CI: 76–84) by 6 years. The risk of any musculoskeletal pain decreased from 37.2% (95% CI: 25.5%–48.9%) to 11.0% (95% CI: 4.3%–17.6%) by 6 years. Mediation analysis revealed that the effect of time since surgery on walk time, resting HR, and HR recovery occurred through a weight‐dependent mechanism. For posttest HR and HR difference, there was both a significant weight‐dependent and weight‐independent mechanism. The effect of surgery on the risk of musculoskeletal pain occurred through a weight‐independent mechanism.ConclusionsAdolescents who underwent MBS experienced significant, durable improvement in mobility and pain, despite weight regain. Our models suggest that improvements may occur through a weight‐independent mechanism. 10.1002/oby.24285 http://creativecommons.org/licenses/by/4.0/