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Autori principali:	Leslie J. Heinberg, Alexandra M. Lee, Gary D. Foster, Amy DiVita, Matthew Allman, Daniel Rotroff, Carla Bou Dargham, Michelle I. Cardel
Natura:	Artículo Open Access
Pubblicazione:	Wiley 2025
Soggetti:	Obesity
Accesso online:	https://onlinelibrary.wiley.com/doi/10.1002/oby.70056
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Effectiveness of Telemedicine Prescribing and a Long‐Acting Obesity Medication Behavioral Program: A 24‐Week Single‐Arm Study Leslie J. Heinberg Alexandra M. Lee Gary D. Foster Amy DiVita Matthew Allman Daniel Rotroff Carla Bou Dargham Michelle I. Cardel Obesity ABSTRACT Objective Limited data exist on telemedicine prescribing of semaglutide and tirzepatide. The effects of a telehealth obesity management program combining the provision of semaglutide and tirzepatide with a behavioral program tailored for long‐acting antiobesity medications (AOMs) were evaluated. Methods In this single‐arm study, 180 participants recruited from a telehealth medical obesity program received a virtual behavioral program tailored for long‐acting AOMs, Bluetooth wireless scales, and a blood pressure (BP) cuff. Participants' (mean age = 44.1; 91% female; 81% White; mean weight = 102.8 kg) weight, BP, eating habits, dietary quality, physical activity, and side effects were assessed at baseline and at 12 and 24 weeks. Wilcoxon rank sum tests were conducted, and p values were adjusted using a false discovery rate approach. Intent‐to‐treat analysis was performed using last observation carried forward (LOCF). Results Weight loss was 7.2% (SD = 5.2%) at 12 weeks and 12.3% (SD = 6.9%) at 24 weeks ( p < 0.0001). Mean BP declined from 131.0/83.8 (SD = 17.2/12.2) to 122.5/78.7 (SD = 13.7/10.1) at 12 weeks and 120.0/78.2 (SD = 13.5/10.6) at 24 weeks ( p < 0.0001). Participants significantly improved their eating habits, diet quality, and activity. Side effects were markedly lower than in previously reported trials. Conclusions Virtually delivered treatment combining telemedicine and a behavioral program tailored for long‐acting AOMs demonstrated clinically significant improvements in weight, BP, diet, and activity over 24 weeks. Trial Registration ClinicalTrials.gov identifier: NCT06034457 10.1002/oby.70056 http://onlinelibrary.wiley.com/termsAndConditions#vor

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// Anecdotal testing Today and Yesterday seems to indicate destroy() // is called by the garbage collector and everything is good. // Something to keep in mind though. return 0; } /** * Write function that is called when session data is to be saved. * * @param string $sessId The current session ID * @param string $data The session data to write * * @return bool */ public function write($sessId, $data): bool { if ($this->writesDisabled) { return true; } return $this->saveSession($sessId, $data); } /** * A function that is called internally when session data is to be saved. * * @param string $sessId The current session ID * @param string $data The session data to write * * @return bool */ abstract protected function saveSession($sessId, $data): bool; }

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