Image‐Guided Excision of Oral Leukoplakia Using Narrow‐Band Imaging Illumination and Two‐Stage Local Anesthesia
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Wiley Open Access
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| Natura: | Artículo Open Access |
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Wiley
2026
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| _version_ | 1867004963189686272 |
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| author | Shih‐Wei Yang |
| author_facet | Shih‐Wei Yang Shih‐Wei Yang |
| collection | Wiley Open Access |
| contents | Image‐Guided Excision of Oral Leukoplakia Using Narrow‐Band Imaging Illumination and Two‐Stage Local Anesthesia Shih‐Wei Yang Otolaryngology–Head and Neck Surgery Abstract This study evaluated the use of narrow‐band imaging (NBI) to assist in achieving adequate excision of oral leukoplakia with complete removal of lesions. Use of lidocaine combined with a vasoconstrictor for local anesthesia is standard practice in surgery. However, the blanching effect that follows injection can obscure the boundary between oral leukoplakia and the surrounding normal mucosa. A two‐stage local anesthesia protocol was applied: plain lidocaine was first administered for anesthesia, after which the excision margin was defined under NBI illumination using a carbon dioxide laser, followed by lidocaine with epinephrine for resection. Twenty‐one patients (18 men, 3 women) with 50 lesions were treated. All surgical margins were free of residual disease. During at least 12 months of follow‐up, one recurrence occurred, and no malignant transformations were observed. In conclusion, NBI‐guided excision with two‐stage local anesthesia avoids the blanching effect and enhances visualization, facilitates precise margin delineation, and supports complete lesion removal. 10.1002/ohn.70302 http://onlinelibrary.wiley.com/termsAndConditions#vor |
| doi_str_mv | 10.1002/ohn.70302 |
| format | Artículo Open Access |
| id | wiley_oa_10_1002_ohn_70302 |
| institution | Wiley Open Access |
| license_str_mv | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| publishDate | 2026 |
| publisher | Wiley |
| record_format | wiley_oa |
| spellingShingle | Image‐Guided Excision of Oral Leukoplakia Using Narrow‐Band Imaging Illumination and Two‐Stage Local Anesthesia Shih‐Wei Yang Otolaryngology–Head and Neck Surgery Image‐Guided Excision of Oral Leukoplakia Using Narrow‐Band Imaging Illumination and Two‐Stage Local Anesthesia Shih‐Wei Yang Otolaryngology–Head and Neck Surgery Abstract This study evaluated the use of narrow‐band imaging (NBI) to assist in achieving adequate excision of oral leukoplakia with complete removal of lesions. Use of lidocaine combined with a vasoconstrictor for local anesthesia is standard practice in surgery. However, the blanching effect that follows injection can obscure the boundary between oral leukoplakia and the surrounding normal mucosa. A two‐stage local anesthesia protocol was applied: plain lidocaine was first administered for anesthesia, after which the excision margin was defined under NBI illumination using a carbon dioxide laser, followed by lidocaine with epinephrine for resection. Twenty‐one patients (18 men, 3 women) with 50 lesions were treated. All surgical margins were free of residual disease. During at least 12 months of follow‐up, one recurrence occurred, and no malignant transformations were observed. In conclusion, NBI‐guided excision with two‐stage local anesthesia avoids the blanching effect and enhances visualization, facilitates precise margin delineation, and supports complete lesion removal. 10.1002/ohn.70302 http://onlinelibrary.wiley.com/termsAndConditions#vor |
| title | Image‐Guided Excision of Oral Leukoplakia Using Narrow‐Band Imaging Illumination and Two‐Stage Local Anesthesia |
| topic | Otolaryngology–Head and Neck Surgery |
| url | https://aao-hnsfjournals.onlinelibrary.wiley.com/doi/10.1002/ohn.70302 |