Association Between Gastroesophageal Reflux Disease and Laryngeal Disorders: Real‐World Evidence
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| Natura: | Artículo Open Access |
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Wiley
2024
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| author | I‐Yun Lee Yu‐Jen Kuo Ching‐Yuan Wu Yao‐Hsu Yang Wei‐Tai Shih Pei‐Rung Yang Ko‐Jung Chen Yao‐Te Tsai Ming‐Shao Tsai Geng‐He Chang Ming‐Yu Yang Cheng‐Ming Hsu |
| author_facet | I‐Yun Lee Yu‐Jen Kuo Ching‐Yuan Wu Yao‐Hsu Yang Wei‐Tai Shih Pei‐Rung Yang Ko‐Jung Chen Yao‐Te Tsai Ming‐Shao Tsai Geng‐He Chang Ming‐Yu Yang Cheng‐Ming Hsu I‐Yun Lee Yu‐Jen Kuo Ching‐Yuan Wu Yao‐Hsu Yang Wei‐Tai Shih Pei‐Rung Yang Ko‐Jung Chen Yao‐Te Tsai Ming‐Shao Tsai Geng‐He Chang Ming‐Yu Yang Cheng‐Ming Hsu |
| collection | Wiley Open Access |
| contents | Association Between Gastroesophageal Reflux Disease and Laryngeal Disorders: Real‐World Evidence I‐Yun Lee Yu‐Jen Kuo Ching‐Yuan Wu Yao‐Hsu Yang Wei‐Tai Shih Pei‐Rung Yang Ko‐Jung Chen Yao‐Te Tsai Ming‐Shao Tsai Geng‐He Chang Ming‐Yu Yang Cheng‐Ming Hsu Otolaryngology–Head and Neck Surgery AbstractObjectiveThe association between gastroesophageal reflux disease (GERD) and laryngeal disorders remains debatable, although it has been the focus of extensive clinical and laboratory research. We conducted this study to obtain evidence on the association.Study DesignPopulation‐based cohort study.SettingTaiwan National Health Insurance Research Database (NHIRD).MethodsUsing data from Taiwan's NHIRD (January 2000 to December 2018), we performed a population‐based analysis to estimate the risk of laryngeal disorders in patients with GERD and those without GERD.ResultsThe GERD and non‐GERD cohorts comprised 176,319 and 705,276 patients, respectively. The cohorts were matched at a ratio of 1:4 based on sex, age, urbanization level, and income level. The risk of laryngeal disorders was higher in the GERD cohort than in the non‐GERD cohort (adjusted hazard ratio: 1.64; 95% confidence interval: 1.61‐1.67).ConclusionThis study is the first to use population data for identifying the association between GERD and laryngeal disorders for real‐world findings. Our population‐based analysis indicates that patients with GERD have an elevated risk of laryngeal disorders. 10.1002/ohn.980 http://onlinelibrary.wiley.com/termsAndConditions#vor |
| doi_str_mv | 10.1002/ohn.980 |
| format | Artículo Open Access |
| id | wiley_oa_10_1002_ohn_980 |
| institution | Wiley Open Access |
| license_str_mv | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| publishDate | 2024 |
| publisher | Wiley |
| record_format | wiley_oa |
| spellingShingle | Association Between Gastroesophageal Reflux Disease and Laryngeal Disorders: Real‐World Evidence I‐Yun Lee Yu‐Jen Kuo Ching‐Yuan Wu Yao‐Hsu Yang Wei‐Tai Shih Pei‐Rung Yang Ko‐Jung Chen Yao‐Te Tsai Ming‐Shao Tsai Geng‐He Chang Ming‐Yu Yang Cheng‐Ming Hsu Otolaryngology–Head and Neck Surgery Association Between Gastroesophageal Reflux Disease and Laryngeal Disorders: Real‐World Evidence I‐Yun Lee Yu‐Jen Kuo Ching‐Yuan Wu Yao‐Hsu Yang Wei‐Tai Shih Pei‐Rung Yang Ko‐Jung Chen Yao‐Te Tsai Ming‐Shao Tsai Geng‐He Chang Ming‐Yu Yang Cheng‐Ming Hsu Otolaryngology–Head and Neck Surgery AbstractObjectiveThe association between gastroesophageal reflux disease (GERD) and laryngeal disorders remains debatable, although it has been the focus of extensive clinical and laboratory research. We conducted this study to obtain evidence on the association.Study DesignPopulation‐based cohort study.SettingTaiwan National Health Insurance Research Database (NHIRD).MethodsUsing data from Taiwan's NHIRD (January 2000 to December 2018), we performed a population‐based analysis to estimate the risk of laryngeal disorders in patients with GERD and those without GERD.ResultsThe GERD and non‐GERD cohorts comprised 176,319 and 705,276 patients, respectively. The cohorts were matched at a ratio of 1:4 based on sex, age, urbanization level, and income level. The risk of laryngeal disorders was higher in the GERD cohort than in the non‐GERD cohort (adjusted hazard ratio: 1.64; 95% confidence interval: 1.61‐1.67).ConclusionThis study is the first to use population data for identifying the association between GERD and laryngeal disorders for real‐world findings. Our population‐based analysis indicates that patients with GERD have an elevated risk of laryngeal disorders. 10.1002/ohn.980 http://onlinelibrary.wiley.com/termsAndConditions#vor |
| title | Association Between Gastroesophageal Reflux Disease and Laryngeal Disorders: Real‐World Evidence |
| topic | Otolaryngology–Head and Neck Surgery |
| url | https://aao-hnsfjournals.onlinelibrary.wiley.com/doi/10.1002/ohn.980 |