Late Events Occurring After 5 Years in Pediatric Rhabdomyosarcoma: A Report From the Children's Oncology Group

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Main Authors: Sara Kreimer, Wei Xue, Amira Qumseya, Timothy B. Lautz, Archana Shenoy, Susan Hiniker, Dana Casey, Rajkumar Venkatramani, Carola Arndt
Format: Artículo Open Access
Published: Wiley 2024
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author Sara Kreimer
Wei Xue
Amira Qumseya
Timothy B. Lautz
Archana Shenoy
Susan Hiniker
Dana Casey
Rajkumar Venkatramani
Carola Arndt
author_facet Sara Kreimer
Wei Xue
Amira Qumseya
Timothy B. Lautz
Archana Shenoy
Susan Hiniker
Dana Casey
Rajkumar Venkatramani
Carola Arndt
Sara Kreimer
Wei Xue
Amira Qumseya
Timothy B. Lautz
Archana Shenoy
Susan Hiniker
Dana Casey
Rajkumar Venkatramani
Carola Arndt
collection Wiley Open Access
contents Late Events Occurring After 5 Years in Pediatric Rhabdomyosarcoma: A Report From the Children's Oncology Group Sara Kreimer Wei Xue Amira Qumseya Timothy B. Lautz Archana Shenoy Susan Hiniker Dana Casey Rajkumar Venkatramani Carola Arndt Pediatric Blood & Cancer ABSTRACTRhabdomyosarcoma is the most common pediatric soft tissue sarcoma, and 5‐year overall survival exceeds 70%. With more long‐term survivors, it is critical to understand the frequency of late events, including recurrence, second malignant neoplasm, and death, occurring 5 years after diagnosis, and the variables associated with these events. We report late events in patients enrolled on Intergroup Rhabdomyosarcoma Study Group and Children's Oncology Group trials from 1997 to 2013 including D9602, D9803, D9802, ARST0331, ARST0431, ARST0531, and ARST08P1. A late event occurred in 2.9% of 5‐year event‐free survivors supporting guidelines to limit surveillance for these events to 5 years from diagnosis. 10.1002/pbc.31421 http://onlinelibrary.wiley.com/termsAndConditions#vor
doi_str_mv 10.1002/pbc.31421
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institution Wiley Open Access
license_str_mv http://onlinelibrary.wiley.com/termsAndConditions#vor
publishDate 2024
publisher Wiley
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spellingShingle Late Events Occurring After 5 Years in Pediatric Rhabdomyosarcoma: A Report From the Children's Oncology Group
Sara Kreimer
Wei Xue
Amira Qumseya
Timothy B. Lautz
Archana Shenoy
Susan Hiniker
Dana Casey
Rajkumar Venkatramani
Carola Arndt
Pediatric Blood & Cancer
Late Events Occurring After 5 Years in Pediatric Rhabdomyosarcoma: A Report From the Children's Oncology Group Sara Kreimer Wei Xue Amira Qumseya Timothy B. Lautz Archana Shenoy Susan Hiniker Dana Casey Rajkumar Venkatramani Carola Arndt Pediatric Blood & Cancer ABSTRACTRhabdomyosarcoma is the most common pediatric soft tissue sarcoma, and 5‐year overall survival exceeds 70%. With more long‐term survivors, it is critical to understand the frequency of late events, including recurrence, second malignant neoplasm, and death, occurring 5 years after diagnosis, and the variables associated with these events. We report late events in patients enrolled on Intergroup Rhabdomyosarcoma Study Group and Children's Oncology Group trials from 1997 to 2013 including D9602, D9803, D9802, ARST0331, ARST0431, ARST0531, and ARST08P1. A late event occurred in 2.9% of 5‐year event‐free survivors supporting guidelines to limit surveillance for these events to 5 years from diagnosis. 10.1002/pbc.31421 http://onlinelibrary.wiley.com/termsAndConditions#vor
title Late Events Occurring After 5 Years in Pediatric Rhabdomyosarcoma: A Report From the Children's Oncology Group
topic Pediatric Blood & Cancer
url https://onlinelibrary.wiley.com/doi/10.1002/pbc.31421