Engineering diaryl alcohol dehydrogenase KpADH reveals importance of retaining hydration shell in organic solvent tolerance
Fuente:
Wiley Open Access
Guardado en:
| Autores principales: | Lu Zhang, Wei Dai, Shuo Rong, Ulrich Schwaneberg, Guochao Xu, Ye Ni |
|---|---|
| Formato: | Artículo Open Access |
| Publicado: |
Wiley
2024
|
| Materias: | |
| Acceso en línea: | |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
How sensitive are protein hydration shells to electrolyte concentration and protein composition?
por: H. Geraili Daronkola, et al.
Publicado: (2024)
por: H. Geraili Daronkola, et al.
Publicado: (2024)
19F NMR‐based solvent accessibility profiling reveals tryptophan ring‐flip dynamics in a protein
por: Soichiro Kawagoe, et al.
Publicado: (2025)
por: Soichiro Kawagoe, et al.
Publicado: (2025)
Allosteric regulation of L‐lactate dehydrogenase: Beyond effector‐mediated tetramerization
por: Hanfeng Cai, et al.
Publicado: (2025)
por: Hanfeng Cai, et al.
Publicado: (2025)
Structure‐based clustering and mutagenesis of bacterial tannases reveals the importance and diversity of active site‐capping domains
por: Tom Coleman, et al.
Publicado: (2024)
por: Tom Coleman, et al.
Publicado: (2024)
Post‐translational regulation of human D‐3‐phosphoglycerate dehydrogenase in Alzheimer's disease
por: Elena Zerbini, et al.
Publicado: (2026)
por: Elena Zerbini, et al.
Publicado: (2026)
The role of the flexible loop region in the substrate binding and catalytic activity of malate dehydrogenases
por: Varuni K. Jamburuthugoda, et al.
Publicado: (2025)
por: Varuni K. Jamburuthugoda, et al.
Publicado: (2025)
Conformational flexibility associated with remote residues regulates the kinetic properties of glutamate dehydrogenase
por: Barsa Kanchan Jyotshna Godsora, et al.
Publicado: (2025)
por: Barsa Kanchan Jyotshna Godsora, et al.
Publicado: (2025)
Not only an inhibitor: Trehalose enhances the catalytic action exerted on oxaloacetate by rabbit lactate dehydrogenase
por: Alessandra Stefan, et al.
Publicado: (2025)
por: Alessandra Stefan, et al.
Publicado: (2025)
Tertiary and quaternary structure remodeling by occupancy of the substrate binding pocket in a large glutamate dehydrogenase
por: Melisa Lázaro, et al.
Publicado: (2026)
por: Melisa Lázaro, et al.
Publicado: (2026)
Mutational analysis reveals the importance of residues of the access tunnel inhibitor site to human P‐glycoprotein (ABCB1)‐mediated transport
por: Paula B. Salazar, et al.
Publicado: (2024)
por: Paula B. Salazar, et al.
Publicado: (2024)
Accounting for nonuniformity of bulk‐solvent: A mosaic model
por: Pavel V. Afonine, et al.
Publicado: (2024)
por: Pavel V. Afonine, et al.
Publicado: (2024)
The structural basis for the broad aldehyde specificity of the aminoaldehyde dehydrogenase PauC from the human pathogen Pseudomonas aeruginosa
por: Yudy V. Cardona‐Cardona, et al.
Publicado: (2025)
por: Yudy V. Cardona‐Cardona, et al.
Publicado: (2025)
In silico peptide self‐assembly reveals the importance of N‐terminal motifs and the inhibition mechanism of the mutation L38M in α ‐synuclein fibrillation
por: Van T. T. Nguyen, et al.
Publicado: (2026)
por: Van T. T. Nguyen, et al.
Publicado: (2026)
Complete combinatorial mutational enumeration of a protein functional site enables sequence‐landscape mapping and identifies highly‐mutated variants that retain activity
por: Mireia Solà Colom, et al.
Publicado: (2024)
por: Mireia Solà Colom, et al.
Publicado: (2024)
Peptides inhibiting the assembly of monomeric human l‐lactate dehydrogenase into catalytically active homotetramer decrease the synthesis of lactate in cultured cells
por: Alessandra Stefan, et al.
Publicado: (2024)
por: Alessandra Stefan, et al.
Publicado: (2024)
Engineering bio‐brick protein scaffolds for organizing enzyme assemblies
por: Alba Ledesma‐Fernandez, et al.
Publicado: (2024)
por: Alba Ledesma‐Fernandez, et al.
Publicado: (2024)
Hydrophobic interactions of a substrate with L193 on the flexible substrate‐binding loop contribute to 3α‐hydroxysteroid dehydrogenase/carbonyl reductase catalytic efficiency
por: Yan‐Liang Chen, et al.
Publicado: (2026)
por: Yan‐Liang Chen, et al.
Publicado: (2026)
Unperturbed hydration structure involves ADP recognition in the N‐terminal domain of human heat shock protein 90α
por: Yu Hirano, et al.
Publicado: (2026)
por: Yu Hirano, et al.
Publicado: (2026)
Dynamic disorder is crucial for mitochondrial protein import
por: Jakob Schneider, et al.
Publicado: (2026)
por: Jakob Schneider, et al.
Publicado: (2026)
The ligninolytic catalytic network reveals the importance of auxiliary enzymes in lignin biocatalysts.
por: Liang, Congying, et al.
Publicado: (2025)
por: Liang, Congying, et al.
Publicado: (2025)
Engineering a self‐organized enzyme cascade for enhanced cell‐free biosynthesis of 3‐hydroxypropionic acid
por: Hanjoo Jo, et al.
Publicado: (2026)
por: Hanjoo Jo, et al.
Publicado: (2026)
Interfacing bacterial microcompartment shell proteins with genetically encoded condensates
por: Michele Costantino, et al.
Publicado: (2025)
por: Michele Costantino, et al.
Publicado: (2025)
Crystal structure of a putative phosphate binding protein from Synechocystis sp. PCC 6803 reveals an evolutionary hotspot.
por: Wang, Chongyang, et al.
Publicado: (2025)
por: Wang, Chongyang, et al.
Publicado: (2025)
Structural insights into bacterial dimethylsulfoniopropionate import by BCCT-family transporters.
por: Zhang, Yu-Zhong, et al.
Publicado: (2026)
por: Zhang, Yu-Zhong, et al.
Publicado: (2026)
Cryo-EM structure of the QseG-QseE complex reveals an accessory protein-driven two-component system activation mechanism.
por: Gong, Piqian, et al.
Publicado: (2025)
por: Gong, Piqian, et al.
Publicado: (2025)
Orchestrating mitochondrial protein import: The emerging role of DYRK1A in health and disease
por: Sahana Shankar, et al.
Publicado: (2026)
por: Sahana Shankar, et al.
Publicado: (2026)
The importance of input sequence set to consensus‐derived proteins and their relationship to reconstructed ancestral proteins
por: Charlotte Nixon, et al.
Publicado: (2024)
por: Charlotte Nixon, et al.
Publicado: (2024)
Molecular principles of the assembly and construction of a carboxysome shell.
por: Wang, Peng, et al.
Publicado: (2024)
por: Wang, Peng, et al.
Publicado: (2024)
Structure-Guided Subunit Interface Engineering to Improve the Catalytic Efficiency of Dimeric Enzymes of FAH Family.
por: Liang, Bo, et al.
Publicado: (2025)
por: Liang, Bo, et al.
Publicado: (2025)
Structural insights into SHIP2 reveal its membrane regulatory mechanisms
por: Jyoti Gupta, et al.
Publicado: (2026)
por: Jyoti Gupta, et al.
Publicado: (2026)
Cryo‐ EM reveals an ensemble of cytochrome P450 reductase conformations in solution
por: Galina I. Lepesheva, et al.
Publicado: (2026)
por: Galina I. Lepesheva, et al.
Publicado: (2026)
Periplasmic electron transfer network in Geobacter sulfurreducens revealed by biomolecular interaction studies
por: Marisa R. Ferreira, et al.
Publicado: (2024)
por: Marisa R. Ferreira, et al.
Publicado: (2024)
A functional helix shuffled variant of the B domain of Staphylococcus aureus
por: Hanna Bobolowski, et al.
Publicado: (2025)
por: Hanna Bobolowski, et al.
Publicado: (2025)
Diseño de un medio de cultivo sintético para la obtención de una proteína con actividad antitumoral a partir de una bacteria marina
por: Núñez, R.R., et al.
Publicado: (2002)
por: Núñez, R.R., et al.
Publicado: (2002)
KEGG Syntax for comparison of organisms, organism groups, and viruses by conserved gene repertoires
por: Minoru Kanehisa, et al.
Publicado: (2026)
por: Minoru Kanehisa, et al.
Publicado: (2026)
ssRNA bacteriophage metagenomes reveal a diverse set of novel protein families
por: Jānis Rūmnieks, et al.
Publicado: (2026)
por: Jānis Rūmnieks, et al.
Publicado: (2026)
Conformational dynamics in insulin receptor kinase reveal a type III allosteric pocket
por: Jyoti Verma, et al.
Publicado: (2026)
por: Jyoti Verma, et al.
Publicado: (2026)
Elaboration of the Homer1 recognition landscape reveals incomplete divergence of paralogous EVH1 domains
por: Avinoam Singer, et al.
Publicado: (2024)
por: Avinoam Singer, et al.
Publicado: (2024)
Vesiculin reveals the role of the IGF2 C‐domain in receptor specificity within the insulin– IGF system
por: Karolína Mrzílková, et al.
Publicado: (2026)
por: Karolína Mrzílková, et al.
Publicado: (2026)
Role of UDP‐N‐acetylmuramic acid in the regulation of MurA activity revealed by molecular dynamics simulations
por: Maycon Vinicius Damasceno de Oliveira, et al.
Publicado: (2024)
por: Maycon Vinicius Damasceno de Oliveira, et al.
Publicado: (2024)
Ejemplares similares
-
How sensitive are protein hydration shells to electrolyte concentration and protein composition?
por: H. Geraili Daronkola, et al.
Publicado: (2024) -
19F NMR‐based solvent accessibility profiling reveals tryptophan ring‐flip dynamics in a protein
por: Soichiro Kawagoe, et al.
Publicado: (2025) -
Allosteric regulation of L‐lactate dehydrogenase: Beyond effector‐mediated tetramerization
por: Hanfeng Cai, et al.
Publicado: (2025) -
Structure‐based clustering and mutagenesis of bacterial tannases reveals the importance and diversity of active site‐capping domains
por: Tom Coleman, et al.
Publicado: (2024) -
Post‐translational regulation of human D‐3‐phosphoglycerate dehydrogenase in Alzheimer's disease
por: Elena Zerbini, et al.
Publicado: (2026)