Image de couverture de livre

Discovery of a novel homocysteine thiolactone hydrolase and the catalytic activity of its natural variants

Fuente: Wiley Open Access

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Shurong Hou, Huan Liu, Yihui Hu, Jie Zhang, Xingyu Deng, Zhenzhen Li, Yun Zhang, Xiaoxuan Li, Yishuang Li, Lei Ma, Jianzhuang Yao, Xiabin Chen
Format:	Artículo Open Access
Publié:	Wiley 2024
Sujets:	Protein Science
Accès en ligne:	Acceder al recurso
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

Ligand binding Pro ‐miscuity of acylpeptide hydrolase, structural analysis of a detoxifying serine hydrolase
par: Anna J. Kiss‐Szemán, et autres
Publié: (2025)

The role of the flexible loop region in the substrate binding and catalytic activity of malate dehydrogenases
par: Varuni K. Jamburuthugoda, et autres
Publié: (2025)

Disordered N‐termini enhance the thermostability of SGNH ‐hydrolase family polyesterases
par: F. Hafna Ahmed, et autres
Publié: (2025)

Plant prenyltransferases: Diversity, catalytic activities, mechanisms, and application in heterologous production of prenylated natural products.
par: Zhang, Yibo, et autres
Publié: (2026)

A multidomain hydrolase from the thermophile Thermanaeromonas toyohensis degrades high molecular mass forms of polyhydroxybutyrate
par: Stephen Quirk, et autres
Publié: (2025)

The peptidyl‐prolyl cis‐trans isomerase, Pin1, is a regulator of the protein kinase C θ ( PKCθ ) catalytic activity in activated T cells
par: Nikhil Ponnoor Anto, et autres
Publié: (2025)

Structural and functional insights into transcription activation of the essential LysR‐type transcriptional regulators
par: Jing Shi, et autres
Publié: (2024)

Peptides inhibiting the assembly of monomeric human l‐lactate dehydrogenase into catalytically active homotetramer decrease the synthesis of lactate in cultured cells
par: Alessandra Stefan, et autres
Publié: (2024)

Discovery of novel, high‐affinity HBV T‐cell epitopes by molecular dynamics‐augmented proteome‐wide screening
par: Mingchen Yan, et autres
Publié: (2026)

Design and characterization of calprotectin tetramerization variants for probing the role of oligomerization in receptor activation
par: Velia Garcia, et autres
Publié: (2025)

Hydrophobic interactions of a substrate with L193 on the flexible substrate‐binding loop contribute to 3α‐hydroxysteroid dehydrogenase/carbonyl reductase catalytic efficiency
par: Yan‐Liang Chen, et autres
Publié: (2026)

Unveiling catalytic potential and the native role of PETase from Streptomyces sp.
par: Sebastián Rodríguez, et autres
Publié: (2026)

Investigating the structural basis of surfactant protein D oligomerization: The crucial role of Cys15‐Cys15/Cys20‐Cys20 disulfide bond linkage
par: Deng Li, et autres
Publié: (2026)

Cryo-EM structure of the QseG-QseE complex reveals an accessory protein-driven two-component system activation mechanism.
par: Gong, Piqian, et autres
Publié: (2025)

Not only an inhibitor: Trehalose enhances the catalytic action exerted on oxaloacetate by rabbit lactate dehydrogenase
par: Alessandra Stefan, et autres
Publié: (2025)

Phosphorylation of a conserved aspartate in the catalytic site of eukaryotic elongation factor 2 kinase
par: Andrea Piserchio, et autres
Publié: (2025)

Predicting protein-protein interaction with interpretable bilinear attention network.
par: Han, Yong, et autres
Publié: (2025)

Discovery and characterization of a novel alginate lyase PeAly15 and its truncated protein DUF4962 domain from Paenibacillus elgii HSFD1: Elucidation the molecular mechanism of endolytic mode.
par: Wei, Quanfeng, et autres
Publié: (2025)

Evaluating the protonation state of the catalytic Cys25 in cruzain cysteine protease: A target for Chagas disease
par: Clauber H. S. da Costa, et autres
Publié: (2025)

Structural basis for dimerization, catalytic regulation, and substrate selectivity of the chloroplast S9D CGEP protease in Arabidopsis thaliana
par: Jacqueline J. Ehrlich, et autres
Publié: (2026)

Complete combinatorial mutational enumeration of a protein functional site enables sequence‐landscape mapping and identifies highly‐mutated variants that retain activity
par: Mireia Solà Colom, et autres
Publié: (2024)

Crystal structure and catalytic mechanism of PL35 family glycosaminoglycan lyases with an ultrabroad substrate spectrum.
par: Wei, Lin, et autres
Publié: (2025)

Allosteric modulation of NF1 GAP: Differential distributions of catalytically competent populations in loss‐of‐function and gain‐of‐function mutants
par: Liang Xu, et autres
Publié: (2025)

Structures of two LarA ‐like nickel‐pincer nucleotide cofactor‐utilizing enzymes with a single catalytic histidine residue
par: Santhosh Gatreddi, et autres
Publié: (2025)

Complement-activated fragment Ba functions as an antibacterial protein and mediates immune responses in lower vertebrates.
par: Jin, Xiao-Yan, et autres
Publié: (2025)

Amyloid formation of alternatively spliced variants of α‐synuclein
par: Daniel Q. SanGiovanni, et autres
Publié: (2025)

Unveiling the enzymatic activity of a dimeric LDH isoform and its implications for allosteric inhibition strategies
par: Ferran Nadal‐Bufi, et autres
Publié: (2025)

An intrinsically disordered region of Ubp10 regulates its binding and activity on ubiquitinated histone substrates
par: Anneliese M. Faustino, et autres
Publié: (2025)

Identification and characterization of a novel ApeC-containing transmembrane protein family in parasitic flatworms.
par: Ouyang, Jihua, et autres
Publié: (2025)

Comparison of enriched charge variants from different anti‐CD3 bispecific antibodies reveals differential susceptibility of each bispecific arm to post‐translational modification
par: Jennifer B. Nguyen, et autres
Publié: (2025)

MAVISp : A modular structure‐based framework for protein variant effects
par: Matteo Arnaudi, et autres
Publié: (2026)

A functional helix shuffled variant of the B domain of Staphylococcus aureus
par: Hanna Bobolowski, et autres
Publié: (2025)

Supervised learning of protein variant effects across large‐scale mutagenesis datasets
par: Thea K. Schulze, et autres
Publié: (2026)

Structural basis of a microbial trimethylamine transporter.
par: Gao, Chao, et autres
Publié: (2025)

Fish CDK2 recruits Dtx4 to degrade TBK1 through ubiquitination in the antiviral response.
par: Lu, Long-Feng, et autres
Publié: (2026)

An improved variant of tobacco etch virus (TEV) protease that does not need reducing agents
par: Stella M. Davis, et autres
Publié: (2025)

A kinetic gatekeeper: TCR ‐ pMHC dissociation dynamics determine T cell activation efficacy
par: Mingchen Yan, et autres
Publié: (2025)

Structural basis for aerobic anoxygenic photosynthesis in the reaction center-light-harvesting 1 (RC-LH1) supercomplex of Dinoroseobacter shibae.
par: Liu, Ze-Kun, et autres
Publié: (2025)

Bromodomain-containing proteins in the unicellular eukaryote .
par: Zhang, Zhe, et autres
Publié: (2025)

Cellular turnover and degradation of the most common missense cystathionine beta‐synthase variants causing homocystinuria
par: Ela Mijatovic, et autres
Publié: (2024)