Data‐driven evaluation of suitable immunogens for improved antibody selection
Fuente:
Wiley Open Access
Guardado en:
| Autores principales: | Katharina Waury, Hlin Kvartsberg, Henrik Zetterberg, Kaj Blennow, Charlotte E. Teunissen, Sanne Abeln |
|---|---|
| Formato: | Artículo Open Access |
| Publicado: |
Wiley
2025
|
| Materias: | |
| Acceso en línea: | |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
Beyond olfaction: New insights into human odorant binding proteins
por: Mifen Chen, et al.
Publicado: (2026)
por: Mifen Chen, et al.
Publicado: (2026)
Cryo‐ EM structures of engineered Shiga toxin‐based immunogens capable of eliciting neutralizing antibodies with therapeutic potential against hemolytic uremic syndrome
por: Alejandro Ezequiel Cristófalo, et al.
Publicado: (2025)
por: Alejandro Ezequiel Cristófalo, et al.
Publicado: (2025)
Structures of a synthetic antibody selected against and bound to the C‐terminal domain of Clostridium perfringens enterotoxin
por: Chinemerem P. Ogbu, et al.
Publicado: (2025)
por: Chinemerem P. Ogbu, et al.
Publicado: (2025)
Grouped immunogens are hierarchically recognized by host to generate antibodies.
por: Liu, Xiang, et al.
Publicado: (2026)
por: Liu, Xiang, et al.
Publicado: (2026)
Enzymatic, structural, and biophysical characterization of a single‐domain antibody (VHH) selectively and tightly inhibiting neutrophil elastase and exhibiting favorable developability properties
por: Paola Redeghieri, et al.
Publicado: (2024)
por: Paola Redeghieri, et al.
Publicado: (2024)
Kinetic evidence for multiple aggregation pathways in antibody light chain variable domains
por: Sherry Wong, et al.
Publicado: (2024)
por: Sherry Wong, et al.
Publicado: (2024)
Proteome encoded determinants of protein sorting into extracellular vesicles
por: Katharina Waury, et al.
Publicado: (2024)
por: Katharina Waury, et al.
Publicado: (2024)
A comparison of antibody–antigen complex sequence‐to‐structure prediction methods and their systematic biases
por: Katherine Maia McCoy, et al.
Publicado: (2024)
por: Katherine Maia McCoy, et al.
Publicado: (2024)
Universal paratope–epitope interaction patterns in antibody–antigen structures
por: Marta A. S. Perez, et al.
Publicado: (2025)
por: Marta A. S. Perez, et al.
Publicado: (2025)
Improving the solubility of single domain antibodies using VH‐like hallmark residues
por: Yuta Uto, et al.
Publicado: (2025)
por: Yuta Uto, et al.
Publicado: (2025)
Computational design of a soluble mimic of the outer membrane LPS transport protein LptD suitable for screening of antibiotics
por: Wenzhao Dai, et al.
Publicado: (2026)
por: Wenzhao Dai, et al.
Publicado: (2026)
HAIRpred : Prediction of human antibody interacting residues in an antigen from its primary structure
por: Ruchir Sahni, et al.
Publicado: (2025)
por: Ruchir Sahni, et al.
Publicado: (2025)
Thermostability and binding properties of single‐chained Fv fragments derived from therapeutic antibodies
por: Takashi Tadokoro, et al.
Publicado: (2024)
por: Takashi Tadokoro, et al.
Publicado: (2024)
Tetravalent antibodies are more potent and efficacious erythropoiesis‐stimulating agents than erythropoietin in vivo
por: Jarrett J. Adams, et al.
Publicado: (2026)
por: Jarrett J. Adams, et al.
Publicado: (2026)
Combining computational modeling and experimental library screening to affinity‐mature VEEV ‐neutralizing antibody F5
por: Christopher A. Sumner, et al.
Publicado: (2025)
por: Christopher A. Sumner, et al.
Publicado: (2025)
Taming interleukin‐12: Engineering of bispecific antibody‐based IL‐12 mimetics with biased agonism capacities
por: Britta Lipinski, et al.
Publicado: (2025)
por: Britta Lipinski, et al.
Publicado: (2025)
Heat‐sterilizable antibody mimics designed on the cold shock protein scaffold from hyperthermophile Thermotoga maritima
por: Hiroshi Amesaka, et al.
Publicado: (2024)
por: Hiroshi Amesaka, et al.
Publicado: (2024)
Structure‐based development of a canine TNF‐α‐specific antibody using adalimumab as a template
por: Cheng‐Chung Lee, et al.
Publicado: (2024)
por: Cheng‐Chung Lee, et al.
Publicado: (2024)
FASTIA: A rapid and accessible platform for protein variant interaction analysis demonstrated with a single‐domain antibody
por: Ryo Matsunaga, et al.
Publicado: (2025)
por: Ryo Matsunaga, et al.
Publicado: (2025)
Using extension‐based mRNA display to design antibody‐like proteinogenic peptides for human PD‐L1
por: Justin N. Ong, et al.
Publicado: (2025)
por: Justin N. Ong, et al.
Publicado: (2025)
Discovery of broadly‐neutralizing antibodies against brown recluse spider and Gadim scorpion sphingomyelinases using consensus toxins as antigens
por: Esperanza Rivera‐de‐Torre, et al.
Publicado: (2024)
por: Esperanza Rivera‐de‐Torre, et al.
Publicado: (2024)
Characterization of high affinity IgM and IgG monoclonal antibodies against norovirus variants GII .4 and GII .17
por: Jumpei Tagawa, et al.
Publicado: (2026)
por: Jumpei Tagawa, et al.
Publicado: (2026)
Human IgE monoclonal antibodies define two unusual epitopes trapping dog allergen Can f 1 in different conformations
por: Kriti Khatri, et al.
Publicado: (2025)
por: Kriti Khatri, et al.
Publicado: (2025)
Structural basis for uPAR binding to an antibody developed for targeted cancer therapy. Mechanistic insights into flexibility, ligand recognition, and molecular imaging
por: Rex F. Anane, et al.
Publicado: (2026)
por: Rex F. Anane, et al.
Publicado: (2026)
Comparison of enriched charge variants from different anti‐CD3 bispecific antibodies reveals differential susceptibility of each bispecific arm to post‐translational modification
por: Jennifer B. Nguyen, et al.
Publicado: (2025)
por: Jennifer B. Nguyen, et al.
Publicado: (2025)
Correction to “Human IgE monoclonal antibodies define two unusual epitopes trapping dog allergen Can f 1 in different conformations”
Publicado: (2025)
Publicado: (2025)
Integrating molecular dynamics simulation with small‐ and wide‐angle X‐ray scattering to unravel the flexibility, antigen‐blocking, and protease‐restoring functions in a hindrance‐based pro‐antibody
por: Jun Min Liao, et al.
Publicado: (2024)
por: Jun Min Liao, et al.
Publicado: (2024)
Substrate selectivity and inhibition of the human lysyl hydroxylase JMJD7
por: Nurgül Bilgin, et al.
Publicado: (2024)
por: Nurgül Bilgin, et al.
Publicado: (2024)
Ligand‐driven modulation of chaperone–cochaperone networks shapes proteostasis outcomes
por: Andrea Magni, et al.
Publicado: (2026)
por: Andrea Magni, et al.
Publicado: (2026)
An improved variant of tobacco etch virus (TEV) protease that does not need reducing agents
por: Stella M. Davis, et al.
Publicado: (2025)
por: Stella M. Davis, et al.
Publicado: (2025)
An improved nerve agent bioscavenger based on the fast self‐reactivation mechanism of porcine butyrylcholinesterase
por: Xavier Brazzolotto, et al.
Publicado: (2026)
por: Xavier Brazzolotto, et al.
Publicado: (2026)
Cell surface β‐lactamase recruitment: A facile selection to identify protein–protein interactions
por: Jordan A. Hinmon, et al.
Publicado: (2024)
por: Jordan A. Hinmon, et al.
Publicado: (2024)
Chromosome segregation in a minimal bacterial cell driven by SMC protein complexes
por: Andrew K. Maytin, et al.
Publicado: (2026)
por: Andrew K. Maytin, et al.
Publicado: (2026)
Aggregation‐driven expression of liraglutide precursors using engineered mini‐tags in Escherichia coli
por: Pavan Reddy Regatti, et al.
Publicado: (2026)
por: Pavan Reddy Regatti, et al.
Publicado: (2026)
Docking guidance with experimental ligand structural density improves docking pose prediction and virtual screening performance
por: Althea T. Hansel‐Harris, et al.
Publicado: (2025)
por: Althea T. Hansel‐Harris, et al.
Publicado: (2025)
Structural basis for dimerization, catalytic regulation, and substrate selectivity of the chloroplast S9D CGEP protease in Arabidopsis thaliana
por: Jacqueline J. Ehrlich, et al.
Publicado: (2026)
por: Jacqueline J. Ehrlich, et al.
Publicado: (2026)
Correction to “Aggregation‐driven expression of liraglutide precursors using engineered mini‐tags in Escherichia coli ”
Publicado: (2026)
Publicado: (2026)
A la carte bioprospecting of substrate‐selective laccases via high‐throughput computational enzyme–substrate interaction profiling
por: Ruite Xiang, et al.
Publicado: (2026)
por: Ruite Xiang, et al.
Publicado: (2026)
Engineering membrane‐bound alkane monooxygenase from Marinobacter sp. for increased activity in the selective ω‐hydroxylation of linear and branched aliphatic esters
por: Jelena Spasic, et al.
Publicado: (2026)
por: Jelena Spasic, et al.
Publicado: (2026)
The importance of input sequence set to consensus‐derived proteins and their relationship to reconstructed ancestral proteins
por: Charlotte Nixon, et al.
Publicado: (2024)
por: Charlotte Nixon, et al.
Publicado: (2024)
Ejemplares similares
-
Beyond olfaction: New insights into human odorant binding proteins
por: Mifen Chen, et al.
Publicado: (2026) -
Cryo‐ EM structures of engineered Shiga toxin‐based immunogens capable of eliciting neutralizing antibodies with therapeutic potential against hemolytic uremic syndrome
por: Alejandro Ezequiel Cristófalo, et al.
Publicado: (2025) -
Structures of a synthetic antibody selected against and bound to the C‐terminal domain of Clostridium perfringens enterotoxin
por: Chinemerem P. Ogbu, et al.
Publicado: (2025) -
Grouped immunogens are hierarchically recognized by host to generate antibodies.
por: Liu, Xiang, et al.
Publicado: (2026) -
Enzymatic, structural, and biophysical characterization of a single‐domain antibody (VHH) selectively and tightly inhibiting neutrophil elastase and exhibiting favorable developability properties
por: Paola Redeghieri, et al.
Publicado: (2024)