Computational design of a soluble mimic of the outer membrane LPS transport protein LptD suitable for screening of antibiotics
Fuente:
Wiley Open Access
Saved in:
| Main Authors: | Wenzhao Dai, Wenxuan Hu, Matthias Schuster, Laetitia Rožić, Bernd Roschitzki, Oliver Zerbe |
|---|---|
| Format: | Artículo Open Access |
| Published: |
Wiley
2026
|
| Subjects: | |
| Online Access: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
Delineating redox cooperativity in water‐soluble and membrane multiheme cytochromes through protein design
by: Benjamin J. Hardy, et al.
Published: (2024)
by: Benjamin J. Hardy, et al.
Published: (2024)
Residues within the LptC transmembrane helix are critical for Escherichia coliLptB2FG ATPase regulation
by: Nicholas P. Cina, et al.
Published: (2024)
by: Nicholas P. Cina, et al.
Published: (2024)
The LptC transmembrane helix undergoes a rigid body movement upon LptB2FG cavity collapse
by: Nicholas P. Cina, et al.
Published: (2025)
by: Nicholas P. Cina, et al.
Published: (2025)
Barrel expansion of outer membrane protein G nanopore through β‐hairpin duplication
by: Joshua C. Foster, et al.
Published: (2025)
by: Joshua C. Foster, et al.
Published: (2025)
Correction to “Barrel expansion of outer membrane protein G nanopore through β‐hairpin duplication”
Published: (2025)
Published: (2025)
Heat‐sterilizable antibody mimics designed on the cold shock protein scaffold from hyperthermophile Thermotoga maritima
by: Hiroshi Amesaka, et al.
Published: (2024)
by: Hiroshi Amesaka, et al.
Published: (2024)
Mechanistic insights into uptake, transfer and exchange of metal ions by the three‐metal clusters of a metalloprotein
by: Pengfei Liu, et al.
Published: (2024)
by: Pengfei Liu, et al.
Published: (2024)
Effect of processing on protein solubility of Chlorella sorokiniana dispersions
by: Ruifen Li, et al.
Published: (2024)
by: Ruifen Li, et al.
Published: (2024)
Identifying and quantifying membrane interactions of the protein human cis ‐prenyltransferase
by: Duncan M. Boren, et al.
Published: (2025)
by: Duncan M. Boren, et al.
Published: (2025)
The soluble state of the HIV ‐1 Vpu protein forms a complex with Ca 2+ ‐calmodulin
by: Olamide Ishola, et al.
Published: (2026)
by: Olamide Ishola, et al.
Published: (2026)
Validation of de novo designed water‐soluble and transmembrane β‐barrels by in silico folding and melting
by: Alvaro Martin Hermosilla, et al.
Published: (2024)
by: Alvaro Martin Hermosilla, et al.
Published: (2024)
MemPPI platform for measuring and engineering membrane protein–protein interactions in mammalian cells via split nanoluciferase
by: Weiyi Tang, et al.
Published: (2026)
by: Weiyi Tang, et al.
Published: (2026)
Selection of nanobodies against liponanoparticle‐embedded membrane proteins by yeast‐surface display
by: Greg J. Dodge, et al.
Published: (2025)
by: Greg J. Dodge, et al.
Published: (2025)
Protective roles of highly conserved motif 1 in tardigrade cytosolic‐abundant heat soluble protein in extreme environments
by: Donguk Kang, et al.
Published: (2024)
by: Donguk Kang, et al.
Published: (2024)
MeCP2 is a naturally supercharged protein with cell membrane transduction capabilities
by: Alexander V. Beribisky, et al.
Published: (2024)
by: Alexander V. Beribisky, et al.
Published: (2024)
Solid‐state NMR protocols for unveiling dynamics and (drug) interactions of membrane‐bound proteins
by: Alessia Lasorsa, et al.
Published: (2025)
by: Alessia Lasorsa, et al.
Published: (2025)
International collaborative study on measuring protein solubility index for legumes, oilseeds, cereals, and related products
by: Keshun Liu, et al.
Published: (2024)
by: Keshun Liu, et al.
Published: (2024)
SypC, a symbiont outer membrane vesicle protein, impacts the development of the squid-vibrio partnership.
by: Kuwabara, Jill T, et al.
Published: (2026)
by: Kuwabara, Jill T, et al.
Published: (2026)
Insights into the diversity of CAHS protein function: Response to “Diversity in the protective role(s) of the conserved motif 1 from tardigrade cytoplasmic abundant heat soluble proteins during drying”
by: Donguk Kang, et al.
Published: (2025)
by: Donguk Kang, et al.
Published: (2025)
Multimodal diffusion for joint design of protein sequence and structure
by: Shaowen Zhu, et al.
Published: (2025)
by: Shaowen Zhu, et al.
Published: (2025)
Correlating membrane‐protein dynamics with function: Integrating bioinformatics, molecular dynamics, and single‐molecule FRET
by: Hugh R. Higinbotham, et al.
Published: (2025)
by: Hugh R. Higinbotham, et al.
Published: (2025)
Engineering a bright near‐infrared fluorescent protein by screening a comprehensive phenotypic landscape
by: Devon L. Kulhanek, et al.
Published: (2026)
by: Devon L. Kulhanek, et al.
Published: (2026)
A pipeline for screening small molecule‐enhanced protein stability in a bacterial orphan receptor
by: James J. Siclari, et al.
Published: (2025)
by: James J. Siclari, et al.
Published: (2025)
Predicting protein-protein interaction with interpretable bilinear attention network.
by: Han, Yong, et al.
Published: (2025)
by: Han, Yong, et al.
Published: (2025)
Engineering IGF2 for Lysosome‐targeting chimeras development to target drug‐resistant membrane proteins in tumor therapy
by: Yanchao Pan, et al.
Published: (2025)
by: Yanchao Pan, et al.
Published: (2025)
Functional reconstitution of bacterial ESCRT‐III protein PspA identifies key regions in membrane binding and remodeling
by: Samuel Herianto, et al.
Published: (2025)
by: Samuel Herianto, et al.
Published: (2025)
Functional thermodynamics govern the ligand binding to human cytosolic transport proteins
by: Sebastian Michler, et al.
Published: (2026)
by: Sebastian Michler, et al.
Published: (2026)
DiffPepDock : Efficient protein–peptide docking and binder screening via SE (3)‐equivariant diffusion
by: Yuzhe Wang, et al.
Published: (2025)
by: Yuzhe Wang, et al.
Published: (2025)
Data‐driven evaluation of suitable immunogens for improved antibody selection
by: Katharina Waury, et al.
Published: (2025)
by: Katharina Waury, et al.
Published: (2025)
The many dimeric faces of Lys49 PLA 2 ‐like proteins: Conformational plasticity and membrane binding drive functional dimer states
by: Diane C. A. Lima, et al.
Published: (2026)
by: Diane C. A. Lima, et al.
Published: (2026)
The double histone fold: Structure, functional implications across the tree of life and relevance to protein design
by: Anna Ranaudo, et al.
Published: (2026)
by: Anna Ranaudo, et al.
Published: (2026)
Multifactorial interaction and influence of culture conditions on yellow fluorescent protein production in Phaeodactylum tricornutum.
by: Augustine, Arun, et al.
Published: (2025)
by: Augustine, Arun, et al.
Published: (2025)
Length matters: the disordered N-terminus of Pal coordinates Lpp exclusion for outer membrane constriction in .
by: Chen, Zhuo-Wei, et al.
Published: (2026)
by: Chen, Zhuo-Wei, et al.
Published: (2026)
Screening de novo designed protein binders in unpurified lysate using flow induced dispersion analysis
by: Francisca Pinheiro, et al.
Published: (2025)
by: Francisca Pinheiro, et al.
Published: (2025)
Toward physics‐based precision medicine: Exploiting protein dynamics to design new therapeutics and interpret variants
by: Artur Meller, et al.
Published: (2024)
by: Artur Meller, et al.
Published: (2024)
Amino acid sequence encodes protein abundance shaped by protein stability at reduced synthesis cost
by: Filip Buric, et al.
Published: (2024)
by: Filip Buric, et al.
Published: (2024)
Design of a water‐soluble CD20 antigen with computational epitope scaffolding
by: Zhiyuan Yao, et al.
Published: (2025)
by: Zhiyuan Yao, et al.
Published: (2025)
Improving the solubility of single domain antibodies using VH‐like hallmark residues
by: Yuta Uto, et al.
Published: (2025)
by: Yuta Uto, et al.
Published: (2025)
Structural basis of a microbial trimethylamine transporter.
by: Gao, Chao, et al.
Published: (2025)
by: Gao, Chao, et al.
Published: (2025)
Structural insights into peptidoglycan glycosidase EtgA binding to the inner rod protein EscI of the type III secretion system via a designed EscI‐EtgA fusion protein
by: J. Boorman, et al.
Published: (2024)
by: J. Boorman, et al.
Published: (2024)
Similar Items
-
Delineating redox cooperativity in water‐soluble and membrane multiheme cytochromes through protein design
by: Benjamin J. Hardy, et al.
Published: (2024) -
Residues within the LptC transmembrane helix are critical for Escherichia coliLptB2FG ATPase regulation
by: Nicholas P. Cina, et al.
Published: (2024) -
The LptC transmembrane helix undergoes a rigid body movement upon LptB2FG cavity collapse
by: Nicholas P. Cina, et al.
Published: (2025) -
Barrel expansion of outer membrane protein G nanopore through β‐hairpin duplication
by: Joshua C. Foster, et al.
Published: (2025) -
Correction to “Barrel expansion of outer membrane protein G nanopore through β‐hairpin duplication”
Published: (2025)