Coptisine Improves Liver Inflammation in Sepsis by Regulating STAT1/IRF1/GPX4 Signaling‐Mediated Kupffer Cells Ferroptosis
Fuente:
Wiley Open Access
Saved in:
| Main Authors: | Bingwen Zhu, Chang Sun, Dongrong Luo, Yuying Liang, Aolin Jiang, Zehui Jiang, Haihua Luo, Gang Yuan, Chenyang Huang, Shaoqing Liu, Lei Li, Yong Jiang |
|---|---|
| Format: | Artículo Open Access |
| Published: |
Wiley
2025
|
| Subjects: | |
| Online Access: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
Embelin Mitigates the Impact of Perinatal Inflammation on Neuron Development by Inhibiting 5‐Lipoxygenase‐Mediated Ferroptosis
by: Feng Zhang, et al.
Published: (2025)
by: Feng Zhang, et al.
Published: (2025)
Integrated Microbiome and Metabolomic to Explore the Mechanism of Coptisine in Alleviating Ulcerative Colitis
by: Wenbin Wu, et al.
Published: (2024)
by: Wenbin Wu, et al.
Published: (2024)
Crocin Attenuates Nrf2/ GPX4 Mediated Ferroptosis in Obstructive Nephropathy by Selectively Targeting MKK4
by: Ziyun Xu, et al.
Published: (2025)
by: Ziyun Xu, et al.
Published: (2025)
Saikosaponin D Alleviates Liver Ischemia–Reperfusion Injury by Inhibiting Mitophagy‐Associated Ferroptosis via the STAT3 / PINK1 Pathway
by: Xingyun Liu, et al.
Published: (2026)
by: Xingyun Liu, et al.
Published: (2026)
Calycosin Targets the CYP1B1 ‐ AKT / SP1 ‐ GPX4 Axis to Modulate Ferroptosis in Colorectal Carcinogenesis
by: Lihan Bie, et al.
Published: (2026)
by: Lihan Bie, et al.
Published: (2026)
4′‐Hydroxychalcone Induces Ferroptosis in Glioblastoma Through the xCT/GSH/GPX4 Axis Under the Regulation of the AKT/mTORC1/4EBP1 Pathway
by: Renshuang Zhao, et al.
Published: (2025)
by: Renshuang Zhao, et al.
Published: (2025)
Harringtonine Elicits Ferroptosis by Regulating SYVN1 ‐Mediated FASN Ubiquitination for Evoking Anti‐Lung Cancer Efficacy
by: Ning Han, et al.
Published: (2025)
by: Ning Han, et al.
Published: (2025)
Daphnetin Alleviates Liver Fibrosis by Inducing Ferritinophagy‐Mediated Ferroptosis in Activated Hepatic Stellate Cells
by: Laiyu Zhu, et al.
Published: (2025)
by: Laiyu Zhu, et al.
Published: (2025)
Scutellarein Attenuates Intervertebral Disc Degeneration by Promoting PINK1 /Parkin‐Mediated Mitophagy to Alleviate Inflammation, Ferroptosis, and Mitochondrial Dysfunction in Nucleus Pulposus Cells
by: Shuanggong Liu, et al.
Published: (2026)
by: Shuanggong Liu, et al.
Published: (2026)
(+)‐Matairesinol, Derived From Olive Oil, Enhanced T‐Cell Anti‐Tumor Immune via JAK3 ‐ STAT1 Signal and Synergized With Anti‐ PD ‐1 Efficacy
by: Zhi Dai, et al.
Published: (2026)
by: Zhi Dai, et al.
Published: (2026)
Ingenol‐Mediated SIRT1 ‐ LXRα Signaling Reduces Lipid Accumulation and Alleviates Postmenopausal Liver Damage
by: Meijing Liu, et al.
Published: (2026)
by: Meijing Liu, et al.
Published: (2026)
Punicalagin Alleviates Acute Liver Injury via Dual STAT1 / NF ‐ κB Inhibition and STAT3 Activation to Orchestrate M1‐to‐M2 Macrophage Polarization
by: Yixuan Huang, et al.
Published: (2026)
by: Yixuan Huang, et al.
Published: (2026)
Dehydrocorydaline Promotes STAT3 /Bcl‐2 Axis‐Mediated Macrophage Efferocytosis to Attenuate Apoptosis in Atherosclerotic Plaques
by: Li Hongzheng, et al.
Published: (2026)
by: Li Hongzheng, et al.
Published: (2026)
Costunolide Ameliorates Hepatic Steatosis and Insulin Resistance in a Diet‐Induced Mouse Model of Metabolic Dysfunction‐Associated Steatotic Liver Disease by Activating the AMPK / ACC1 Signalling Pathway
by: Wen Jiang, et al.
Published: (2026)
by: Wen Jiang, et al.
Published: (2026)
Non‐Apoptotic Inhibition of Colorectal Cancer Proliferation by Sclareol via Ferroptosis Involving SLC7A11/GPX4 Modulation
by: Yu‐Xi Li, et al.
Published: (2025)
by: Yu‐Xi Li, et al.
Published: (2025)
Platycodin D2 Mediates Incomplete Autophagy and Ferroptosis in Breast Cancer Cells by Regulating Mitochondrial ROS
by: Yaru Li, et al.
Published: (2024)
by: Yaru Li, et al.
Published: (2024)
Bavachinin Suppresses the Growth of Melanoma Cells by eEF2K / eEF2 Signaling and Induces Autophagy
by: Yufang Lin, et al.
Published: (2026)
by: Yufang Lin, et al.
Published: (2026)
Ginsenoside Rg5 Ameliorates Ferroptosis in Ethanol‐Induced Acute Liver Injury by Activating FTO ‐ YTHDF2 ‐Nrf2 Signal
by: Guan‐Yue Shan, et al.
Published: (2026)
by: Guan‐Yue Shan, et al.
Published: (2026)
Kaempferol Suppresses Abdominal Aortic Aneurysm Development via Modulation of Macrophage Polarization Through the STAT / TNF Signaling Pathway
by: Mengsha Li, et al.
Published: (2026)
by: Mengsha Li, et al.
Published: (2026)
Salvianolic Acid B Inhibits ZBP1‐Mediated PANoptosis in Mycobacterium tuberculosis‐Infected Macrophages by Targeting TNFR1
by: Jingjing Shen, et al.
Published: (2025)
by: Jingjing Shen, et al.
Published: (2025)
Maslinic Acid Ameliorates DSS‐Induced Experimental Colitis by Suppressing Th Cell‐Mediated Inflammation via AICD Induction
by: Dan Li, et al.
Published: (2025)
by: Dan Li, et al.
Published: (2025)
Oleanolic Acid Up‐Regulated UGT1A1 and Antagonized Inflammation by Affecting the Binding of PXR and PKCα to HSP90α and SRC1
by: Suqin Zhu, et al.
Published: (2025)
by: Suqin Zhu, et al.
Published: (2025)
Ilexgenin A Alleviates Myocardial Ferroptosis in Response to Ischemia Reperfusion Injury via the SIRT1 Pathway
by: Bo Yang, et al.
Published: (2024)
by: Bo Yang, et al.
Published: (2024)
Z‐Guggulsterone Induces Ferroptosis in Chemoresistant Breast Cancer via a CDKN2B ‐Mediated Suppression of GTP Cyclohydrolase 1
by: Zhuo‐Tao Yang, et al.
Published: (2026)
by: Zhuo‐Tao Yang, et al.
Published: (2026)
Astragaloside IV Alleviates Acute Hepatic Injury by Regulating Macrophage Polarization and Pyroptosis via Activation of the AMPK / SIRT1 Signaling Pathway
by: Gang Kuang, et al.
Published: (2024)
by: Gang Kuang, et al.
Published: (2024)
Xanthohumol Regulates Mitophagy in Osteosarcoma Cells via AMPK‐ULK1‐FUNDC1 Signaling Pathway
by: Qiaofeng Ge, et al.
Published: (2025)
by: Qiaofeng Ge, et al.
Published: (2025)
Formononetin Induces Ferroptosis in Activated Hepatic Stellate Cells to Attenuate Liver Fibrosis by Targeting NADPH Oxidase 4
by: Ming‐xuan Liu, et al.
Published: (2024)
by: Ming‐xuan Liu, et al.
Published: (2024)
Sappanone A Exerted Strong Anti‐Inflammatory Effects in the Treatment of Atopic Dermatitis Through IL‐21R ‐Mediated JAK1 / STAT3 Pathway
by: Jiayi Li, et al.
Published: (2025)
by: Jiayi Li, et al.
Published: (2025)
Nrf2‐Mediated Ferroptosis Is Involved in Berberine‐Induced Alleviation of Diabetic Kidney Disease
by: Kun Gao, et al.
Published: (2025)
by: Kun Gao, et al.
Published: (2025)
Mechanism Study on Liquiritin Alleviating Nociceptive Sensitization in Knee Osteoarthritis via Promoting M2 Macrophage Polarization Through Regulation of the Rap1/ PI3K /Akt Signaling Pathway
by: Hou‐Yu Fu, et al.
Published: (2026)
by: Hou‐Yu Fu, et al.
Published: (2026)
Isorhyncophylline Targets PP2AC to Modulate YAP to Inhibit Endothelial Cell Inflammation
by: Lihua Wang, et al.
Published: (2026)
by: Lihua Wang, et al.
Published: (2026)
Hydroxytyrosol Improves UV ‐Induced Skin Photoaging via PI3K ‐ AKT / MAPK / JAK ‐ STAT and NF ‐ κB Pathways: Insights From Keratinocytes and In Vivo Validation
by: Enhui Wang, et al.
Published: (2026)
by: Enhui Wang, et al.
Published: (2026)
Polydatin Alleviated Ischemia–Reperfusion Induced Kidney Injury by Inhibiting SETD2‐Mediated Ferroptosis
by: Mu He, et al.
Published: (2025)
by: Mu He, et al.
Published: (2025)
Scutellarin Attenuates Lipopolysaccharide‐Induced Acute Lung Injury in Mice by Inhibiting M1 Macrophage Polarization via the GBP2 / JAK2 / STAT3 Signaling Pathway
by: Jiajia Tang, et al.
Published: (2025)
by: Jiajia Tang, et al.
Published: (2025)
Quercetin Overcomes Cisplatin Resistance by Inducing Ferroptosis via the DDB2 ‐ AS1 / miR ‐4728‐5p/p53 Axis
by: Meng Li, et al.
Published: (2026)
by: Meng Li, et al.
Published: (2026)
Curcumin Alleviates Bone Cancer Pain by Inhibiting Satellite Glial Cell Activity via Janus Kinase 1/Signal Transducer and Transcription 3 Pathway Activator
by: Xinchao Jiang, et al.
Published: (2026)
by: Xinchao Jiang, et al.
Published: (2026)
Columbianadin Ameliorates Bleomycin‐Induced Pulmonary Fibrosis by Inhibiting Cellular Senescence via the AMPK –Sirt1/3 Signaling Pathway
by: Zeng Qian, et al.
Published: (2026)
by: Zeng Qian, et al.
Published: (2026)
Mechanisms of Mulberry Leaf Extracts Ameliorating Inflammation and Fibrosis in Non‐Alcoholic Fatty Liver Disease Mice via NF‐κB and TGFβ1/Smad3 Pathways
by: Shunying Li, et al.
Published: (2026)
by: Shunying Li, et al.
Published: (2026)
Icaritin Sensitizes Hepatocellular Carcinoma to PD ‐ L1 Therapy by NQO1 ‐Dependent Ferroptosis Induction
by: Zhen Li, et al.
Published: (2026)
by: Zhen Li, et al.
Published: (2026)
Oxymatrine Alleviates Atherosclerosis by Regulating Macrophage Senescence via the SIRT1 ‐ P53 Signaling Pathway
by: Jun Xiang, et al.
Published: (2026)
by: Jun Xiang, et al.
Published: (2026)
Similar Items
-
Embelin Mitigates the Impact of Perinatal Inflammation on Neuron Development by Inhibiting 5‐Lipoxygenase‐Mediated Ferroptosis
by: Feng Zhang, et al.
Published: (2025) -
Integrated Microbiome and Metabolomic to Explore the Mechanism of Coptisine in Alleviating Ulcerative Colitis
by: Wenbin Wu, et al.
Published: (2024) -
Crocin Attenuates Nrf2/ GPX4 Mediated Ferroptosis in Obstructive Nephropathy by Selectively Targeting MKK4
by: Ziyun Xu, et al.
Published: (2025) -
Saikosaponin D Alleviates Liver Ischemia–Reperfusion Injury by Inhibiting Mitophagy‐Associated Ferroptosis via the STAT3 / PINK1 Pathway
by: Xingyun Liu, et al.
Published: (2026) -
Calycosin Targets the CYP1B1 ‐ AKT / SP1 ‐ GPX4 Axis to Modulate Ferroptosis in Colorectal Carcinogenesis
by: Lihan Bie, et al.
Published: (2026)