Cover Image

Scutellarin Attenuates Lipopolysaccharide‐Induced Acute Lung Injury in Mice by Inhibiting M1 Macrophage Polarization via the GBP2 / JAK2 / STAT3 Signaling Pathway

Fuente: Wiley Open Access

Saved in:

Bibliographic Details
Main Authors:	Jiajia Tang, Yiwei Ding, Wei Chen, Jun Shi, Chunyang Zhang, Xiaoyu Zhao, Jiao Li, Zhihai Han, Xuxin Chen
Format:	Artículo Open Access
Published:	Wiley 2025
Subjects:	Phytotherapy Research
Online Access:	Acceder al recurso
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Punicalagin Alleviates Acute Liver Injury via Dual STAT1 / NF ‐ κB Inhibition and STAT3 Activation to Orchestrate M1‐to‐M2 Macrophage Polarization
by: Yixuan Huang, et al.
Published: (2026)

Isoferulic Acid Mitigates Acute Lung Injury Induced by Sepsis Through the Inhibition of JAK2
by: Tong Xu, et al.
Published: (2025)

The SLCO4A1‐Mediated Transmembrane Transport of Lysionotin Attenuates Acute Lung Injury Through Activating the AMPK/Nrf2 Signaling Pathway
by: Dayan Xiong, et al.
Published: (2025)

Astragaloside IV Alleviates Acute Hepatic Injury by Regulating Macrophage Polarization and Pyroptosis via Activation of the AMPK / SIRT1 Signaling Pathway
by: Gang Kuang, et al.
Published: (2024)

Kaempferol Suppresses Abdominal Aortic Aneurysm Development via Modulation of Macrophage Polarization Through the STAT / TNF Signaling Pathway
by: Mengsha Li, et al.
Published: (2026)

Diallyl Trisulfide Suppresses Tumor‐Associated Macrophage M2 ‐Like Polarization and Recruitment and Improves the Tumor Microenvironment Through Blocking CCL5 / STAT3 Signaling Pathway Against Lung Cancer
by: Chunfeng Xie, et al.
Published: (2025)

Terminalia chebula Extract Alleviates Lipopolysaccharide‐Induced Acute Lung Injury by Modulating the Interleukin‐17‐Dependent Mitogen‐Activated Protein Kinase/Nuclear Factor‐Kappa B Signaling Pathways
by: Huifang Li, et al.
Published: (2026)

Plantaginis Semen, a Novel Natural S1PR1 Agonist, Inhibits Oxidative Stress and Inflammation to Treat Lipopolysaccharide‐Induced Acute Lung Injury
by: WanAi Xu, et al.
Published: (2025)

Hesperidin Inhibits Oxidative Stress and Apoptosis of Granulosa Cells in Polycystic Ovarian Syndrome Through the JAK2 / STAT3 and PI3K / AKT Pathways
by: Qixuan Zhang, et al.
Published: (2025)

Dehydrocorydaline Promotes STAT3 /Bcl‐2 Axis‐Mediated Macrophage Efferocytosis to Attenuate Apoptosis in Atherosclerotic Plaques
by: Li Hongzheng, et al.
Published: (2026)

Saikosaponin D Alleviates Liver Ischemia–Reperfusion Injury by Inhibiting Mitophagy‐Associated Ferroptosis via the STAT3 / PINK1 Pathway
by: Xingyun Liu, et al.
Published: (2026)

Genistein Ameliorates the Ischemic State of Random Skin Flap by Regulating Macrophage Polarization Through AMPK / SIRT1 Signaling Pathway
by: Yuedong Fu, et al.
Published: (2025)

Mangiferin Attenuates Myocardial Ischemia Reperfusion Injury by Regulating the GAS6/Axl Signaling Pathway
by: Aizhen Zhao, et al.
Published: (2025)

Columbianadin Ameliorates Myocardial Injury by Inhibiting Autophagy Through the PI3K/Akt/mTOR Signaling Pathway in AMI Mice and Hypoxic H9c2 Cells
by: Niu Zi‐Chang, et al.
Published: (2024)

Poricoic Acid A, an Active Ingredient Extracted From Poria cocos, Inhibits Lung Cancer Cell Growth by Suppressing MEK/ERK Signaling Pathway
by: Xueni Sun, et al.
Published: (2025)

(+)‐Matairesinol, Derived From Olive Oil, Enhanced T‐Cell Anti‐Tumor Immune via JAK3 ‐ STAT1 Signal and Synergized With Anti‐ PD ‐1 Efficacy
by: Zhi Dai, et al.
Published: (2026)

Icariin Inhibits NF ‐ κB Signaling in Asthmatic Lung Epithelium by Promoting Nrf2 Signaling
by: Shiyuan Wang, et al.
Published: (2025)

Mechanism Study on Liquiritin Alleviating Nociceptive Sensitization in Knee Osteoarthritis via Promoting M2 Macrophage Polarization Through Regulation of the Rap1/ PI3K /Akt Signaling Pathway
by: Hou‐Yu Fu, et al.
Published: (2026)

Magnoflorine alleviates dextran sulfate sodium‐induced ulcerative colitis via inhibiting JAK2/STAT3 signaling pathway
by: Jianxia Wen, et al.
Published: (2024)

Astragalin Inhibits Oxidative Stress‐Induced Pyroptosis and Apoptosis in Mouse Models of Renal Ischemia/Reperfusion Injury by Activating the SIRT1 /Nrf2 Pathway
by: Qian Huang, et al.
Published: (2025)

Oxymatrine Alleviates Atherosclerosis by Regulating Macrophage Senescence via the SIRT1 ‐ P53 Signaling Pathway
by: Jun Xiang, et al.
Published: (2026)

Paeoniflorin Attenuates the Progression of Diabetic Kidney Disease by Regulating Macrophage Differentiation
by: Chunru Shi, et al.
Published: (2025)

Isoliquiritigenin Exhibits Anti‐Inflammatory Responses in Acute Lung Injury by Covalently Binding to the Myeloid Differentiation Protein‐2 Domain
by: Liu Yang, et al.
Published: (2024)

Sappanone A Exerted Strong Anti‐Inflammatory Effects in the Treatment of Atopic Dermatitis Through IL‐21R ‐Mediated JAK1 / STAT3 Pathway
by: Jiayi Li, et al.
Published: (2025)

Atractylenolide I Blocks Lung Metastasis of Triple‐Negative Breast Cancer by Inhibiting SPP1 ‐Mediated Extracellular Matrix Signaling Pathway
by: Qingling Wang, et al.
Published: (2026)

Ginsenoside Rb2 Attenuates Microvascular Endothelial Stress Injury by Mediating Mitochondrial Pathway Pyroptosis via the DNA ‐ PKcs ‐ SIRT5 Axis
by: Xiangyi Pu, et al.
Published: (2026)

Ginsenoside Rg5 Ameliorates Ferroptosis in Ethanol‐Induced Acute Liver Injury by Activating FTO ‐ YTHDF2 ‐Nrf2 Signal
by: Guan‐Yue Shan, et al.
Published: (2026)

Hydroxytyrosol Improves UV ‐Induced Skin Photoaging via PI3K ‐ AKT / MAPK / JAK ‐ STAT and NF ‐ κB Pathways: Insights From Keratinocytes and In Vivo Validation
by: Enhui Wang, et al.
Published: (2026)

Leonurine Maintains BMSCs Stemness From Osteoporotic Rats Through Inhibiting Ferroptosis Depending on the JNK Signaling Pathway
by: Dongmei Lan, et al.
Published: (2026)

Berberine Inhibits Migration and Apoptosis of Rat Podocytes in Diabetic Nephropathy via the Novel lncRNA LOC102549726 Related Pathway
by: Chen Wang, et al.
Published: (2025)

Ginkgo Flavone Aglycone Ameliorates Atherosclerosis via Inhibiting Endothelial Pyroptosis by Activating the Nrf2 Pathway
by: Xingyi Chen, et al.
Published: (2024)

Geniposidic Acid Attenuates Chronic Tubulointerstitial Nephropathy Through Regulation of the NF‐ƙB/Nrf2 Pathway Via Aryl Hydrocarbon Receptor Signaling
by: Yan‐Ni Wang, et al.
Published: (2024)

Scutellarin Alleviates Hepatic Steatosis by Autophagy‐Mediated NCoR1 / PPARα ‐Driven Fatty Acid β‐Oxidation and Enhancing Peroxisome Biogenesis
by: Jianmei Zheng, et al.
Published: (2026)

Fucoxanthin Protects Against Acute Liver Injury by Inhibiting NOD ‐Like Receptor Protein 3 Inflammasome‐Mediated Pyroptosis Through the Mitogen‐Activated Protein Kinases and Nuclear Factor‐Kappa B Pathway
by: Yigang Zheng, et al.
Published: (2026)

Macelignan Improves Functional Recovery After Spinal Cord Injury by Augmenting Autophagy via the AKT‐mTOR‐TFEB Signaling Pathway
by: Yuxuan Zhu, et al.
Published: (2025)

Plumbagin Alleviates Mild Traumatic Brain Injury‐Induced Obsessive‐Compulsive Disorder in Mice by Inhibiting nNOS and Augmenting Cortico‐Striatal Serotonin Levels
by: Kamini R. Shirasath, et al.
Published: (2025)

Emodin Inhibits AIM2 Inflammasome Activation via Modulating K27 ‐Linked Polyubiquitination to Attenuate Renal Fibrosis
by: Lidan Lu, et al.
Published: (2024)

Polydatin Alleviated Ischemia–Reperfusion Induced Kidney Injury by Inhibiting SETD2‐Mediated Ferroptosis
by: Mu He, et al.
Published: (2025)

Pedunculoside Inhibits Hepatocellular Carcinoma Progression by Activating the MAPK Signaling Pathway Through Targeting and Suppressing CDK4
by: Yang Zhou, et al.
Published: (2026)

Tanshinone IIA Alleviates Pulmonary Fibrosis by Inhibiting Pyroptosis of Alveolar Epithelial Cells Through the MAPK Signaling Pathway
by: Yong Xu, et al.
Published: (2024)