Traditional Chinese medicine for gastric cancer: An evidence mapping

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Hauptverfasser: Zelei Dai, Chenfeng Tan, Jun Wang, Qin Wang, Ying Wang, Ying He, Yalan Peng, Mingyou Gao, Yonggang Zhang, Lei Liu, Ningying Song, Nian Li
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Veröffentlicht: Wiley 2024
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author Zelei Dai
Chenfeng Tan
Jun Wang
Qin Wang
Ying Wang
Ying He
Yalan Peng
Mingyou Gao
Yonggang Zhang
Lei Liu
Ningying Song
Nian Li
author_facet Zelei Dai
Chenfeng Tan
Jun Wang
Qin Wang
Ying Wang
Ying He
Yalan Peng
Mingyou Gao
Yonggang Zhang
Lei Liu
Ningying Song
Nian Li
Zelei Dai
Chenfeng Tan
Jun Wang
Qin Wang
Ying Wang
Ying He
Yalan Peng
Mingyou Gao
Yonggang Zhang
Lei Liu
Ningying Song
Nian Li
collection Wiley Open Access
contents Traditional Chinese medicine for gastric cancer: An evidence mapping Zelei Dai Chenfeng Tan Jun Wang Qin Wang Ying Wang Ying He Yalan Peng Mingyou Gao Yonggang Zhang Lei Liu Ningying Song Nian Li Phytotherapy Research AbstractAs a complementary and alternative therapy, traditional Chinese medicine (TCM) has been playing a significant role in gastric cancer treatment. Data from individual systematic reviews have not been comprehensively summarized, and the relationship between certain interventions and outcomes are ill‐defined. This study aimed to analyze the advantages of TCM interventions for gastric cancer by the method of evidence mapping. We searched PubMed, Embase, Web of Science, China National Knowledge Infrastructure, Chinese Scientific Journals Database, and Wanfang Database for systematic reviews of TCM treating gastric cancer up to December 31, 2023. We used Excel, Endnote 20, and Python software for the analysis of incorporated studies. We assessed the quality of included SRs by AMSTAR‐2 and performed evidence mapping including 89 SRs, 1648 RCTs and 122,902 patients, identifying 47 types of interventions and 39 types of outcomes. From a visual overview, we displayed that most SRs reported beneficial effects in improving short‐ and long‐term survival, myelosuppression, and immune function, even though the quality of evidence was generally low. The benefits of Brucea javanica Oil Emulsion Injection, ShenQiFuZheng Injection, XiaoAiPing, Astragalus‐Containing TCM and Guben Xiaoji Therapy were found the most solid in corresponding aspects. Our findings suggest that although more rigorous clinical trials and SRs are needed to identify the precise effectiveness, integrating such evidence into clinical care of gastric cancer is expected to be beneficial. 10.1002/ptr.8155 http://onlinelibrary.wiley.com/termsAndConditions#vor
doi_str_mv 10.1002/ptr.8155
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publishDate 2024
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spellingShingle Traditional Chinese medicine for gastric cancer: An evidence mapping
Zelei Dai
Chenfeng Tan
Jun Wang
Qin Wang
Ying Wang
Ying He
Yalan Peng
Mingyou Gao
Yonggang Zhang
Lei Liu
Ningying Song
Nian Li
Phytotherapy Research
Traditional Chinese medicine for gastric cancer: An evidence mapping Zelei Dai Chenfeng Tan Jun Wang Qin Wang Ying Wang Ying He Yalan Peng Mingyou Gao Yonggang Zhang Lei Liu Ningying Song Nian Li Phytotherapy Research AbstractAs a complementary and alternative therapy, traditional Chinese medicine (TCM) has been playing a significant role in gastric cancer treatment. Data from individual systematic reviews have not been comprehensively summarized, and the relationship between certain interventions and outcomes are ill‐defined. This study aimed to analyze the advantages of TCM interventions for gastric cancer by the method of evidence mapping. We searched PubMed, Embase, Web of Science, China National Knowledge Infrastructure, Chinese Scientific Journals Database, and Wanfang Database for systematic reviews of TCM treating gastric cancer up to December 31, 2023. We used Excel, Endnote 20, and Python software for the analysis of incorporated studies. We assessed the quality of included SRs by AMSTAR‐2 and performed evidence mapping including 89 SRs, 1648 RCTs and 122,902 patients, identifying 47 types of interventions and 39 types of outcomes. From a visual overview, we displayed that most SRs reported beneficial effects in improving short‐ and long‐term survival, myelosuppression, and immune function, even though the quality of evidence was generally low. The benefits of Brucea javanica Oil Emulsion Injection, ShenQiFuZheng Injection, XiaoAiPing, Astragalus‐Containing TCM and Guben Xiaoji Therapy were found the most solid in corresponding aspects. Our findings suggest that although more rigorous clinical trials and SRs are needed to identify the precise effectiveness, integrating such evidence into clinical care of gastric cancer is expected to be beneficial. 10.1002/ptr.8155 http://onlinelibrary.wiley.com/termsAndConditions#vor
title Traditional Chinese medicine for gastric cancer: An evidence mapping
topic Phytotherapy Research
url https://onlinelibrary.wiley.com/doi/10.1002/ptr.8155