Cucurbitacin B attenuates osteoarthritis development by inhibiting NLRP3 inflammasome activation and pyroptosis through activating Nrf2/HO‐1 pathway
Fuente:
Wiley Open Access
Saved in:
| Main Authors: | Chao Lou, Yuqin Fang, Yifan Mei, Wei Hu, Liaojun Sun, Chen Jin, Hua Chen, Wenhao Zheng |
|---|---|
| Format: | Artículo Open Access |
| Published: |
Wiley
2024
|
| Subjects: | |
| Online Access: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
Cucurbitacin B modulates M2 macrophage differentiation and attenuates osteosarcoma progression via PI3K/AKT pathway
by: Hong Wu, et al.
Published: (2024)
by: Hong Wu, et al.
Published: (2024)
20(R)‐ginsenoside Rg3 attenuates cerebral ischemia–reperfusion injury by mitigating mitochondrial oxidative stress via the Nrf2/HO‐1 signaling pathway
by: Deyun Chen, et al.
Published: (2024)
by: Deyun Chen, et al.
Published: (2024)
Mechanism of Cucurbitacin B Targeting ZNF70 / NLRP3 Axis Against Inflammation‐Associated Colorectal Cancer
by: Shen Cao, et al.
Published: (2026)
by: Shen Cao, et al.
Published: (2026)
Dihydroartemisinin‐driven TOM70 inhibition leads to mitochondrial destabilization to induce pyroptosis against lung cancer
by: Liu‐Gen Li, et al.
Published: (2024)
by: Liu‐Gen Li, et al.
Published: (2024)
Mitochondrial‐targeted curcumin inhibits T‐cell activation via Nrf2 and inhibits graft‐versus‐host‐disease in a mouse model
by: Raghavendra S. Patwardhan, et al.
Published: (2024)
by: Raghavendra S. Patwardhan, et al.
Published: (2024)
Dihydrocapsaicin suppresses the STING‐mediated accumulation of ROS and NLRP3 inflammasome and alleviates apoptosis after ischemia–reperfusion injury of perforator skin flap
by: Yingying Lai, et al.
Published: (2024)
by: Yingying Lai, et al.
Published: (2024)
Hesperetin promotes diabetic wound healing by inhibiting ferroptosis through the activation of SIRT3
by: Xianbin Yu, et al.
Published: (2024)
by: Xianbin Yu, et al.
Published: (2024)
Neurological recovery and neurogenesis by curcumin sustained‐release system cross‐linked with an acellular spinal cord scaffold in rat spinal cord injury: TargetingNLRP3inflammasome pathway
by: Neda Ghaffari, et al.
Published: (2024)
by: Neda Ghaffari, et al.
Published: (2024)
Trifolirhizin reduces osteoclast formation and prevents inflammatory osteolysis by inhibiting RANKL‐induced activation of NF‐κB and MAPK signaling pathways and ROS
by: Jian Huang, et al.
Published: (2024)
by: Jian Huang, et al.
Published: (2024)
Tangeretin alleviates inflammation and oxidative response induced by spinal cord injury by activating the Sesn2/Keap1/Nrf2 pathway
by: Birong Peng, et al.
Published: (2024)
by: Birong Peng, et al.
Published: (2024)
Scutellarein alleviates osteoarthritis progression through the PI3K/Akt/NF‐kappaB signaling pathway: In vitro and in vivo studies
by: Ziyang Ye, et al.
Published: (2024)
by: Ziyang Ye, et al.
Published: (2024)
Multifaceted Therapeutic Impacts of Cucurbitacin B: Recent Evidences From Preclinical Studies
by: Meenal Sahu, et al.
Published: (2025)
by: Meenal Sahu, et al.
Published: (2025)
Jatrorrhizine alleviates cytokine storm secondary lung injury via regulating CD39‐dominant purinergic braking and downstream NLRP3 inflammasome
by: Yuejia Lan, et al.
Published: (2025)
by: Yuejia Lan, et al.
Published: (2025)
Natural xanthones as modulators of the Nrf2/ARE signaling pathway and potential gastroprotective agents
by: Natalie Vivien Gunter, et al.
Published: (2024)
by: Natalie Vivien Gunter, et al.
Published: (2024)
Harmine promotes megakaryocyte differentiation and thrombopoiesis by activating the Rac1/Cdc42/JNK pathway through a potential target of 5‐HTR2A
by: Xiaoxi Liu, et al.
Published: (2024)
by: Xiaoxi Liu, et al.
Published: (2024)
Tamarixetin ameliorates cerebral ischemia–reperfusion injury via suppressing nicotinamide adenine dinucleotide phosphate oxidase 2/nucleotide‐binding oligomerization domain like receptor family pyrin domain‐containing 3 inflammasome activation
by: Yanqiu Yang, et al.
Published: (2024)
by: Yanqiu Yang, et al.
Published: (2024)
D‐pinitol alleviates diabetic cardiomyopathy by inhibiting the optineurin‐mediated endoplasmic reticulum stress and glycophagy signaling pathway
by: Xiaoli Li, et al.
Published: (2024)
by: Xiaoli Li, et al.
Published: (2024)
Salidroside improves blood–brain barrier integrity and cognitive function in hypobaric hypoxia mice by inhibiting microglia activation through GSK3β
by: Xianxie Zhang, et al.
Published: (2024)
by: Xianxie Zhang, et al.
Published: (2024)
Quercetin prevented diabetic nephropathy by inhibiting renal tubular epithelial cell apoptosis via the PI3K/AKT pathway
by: Fang Liu, et al.
Published: (2024)
by: Fang Liu, et al.
Published: (2024)
Resveratrol triggers autophagy‐related apoptosis to inhibit the progression of colorectal cancer via inhibition of FOXQ1
by: MinFeng Zhou, et al.
Published: (2024)
by: MinFeng Zhou, et al.
Published: (2024)
Germacrone alleviates breast cancer‐associated osteolysis by inhibiting osteoclastogenesis via inhibition of MAPK/NF‐κB signaling pathways
by: Zhengjun Lin, et al.
Published: (2024)
by: Zhengjun Lin, et al.
Published: (2024)
PTOV1‐AS1 desensitizes colorectal cancer cells to 5‐FU through depressing miR‐149‐5p to activate the positive feedback loop with Wnt/β‐catenin pathway
by: Yanan Chen, et al.
Published: (2024)
by: Yanan Chen, et al.
Published: (2024)
Pomegranate polyphenol punicalin ameliorates lipopolysaccharide‐induced memory impairment, behavioral disorders, oxidative stress, and neuroinflammation via inhibition of TLR4‐NF‐кB pathway
by: Peng Chen, et al.
Published: (2024)
by: Peng Chen, et al.
Published: (2024)
Naringenin inhibits the microsomal triglyceridetransfer protein/apolipoprotein B axis to inhibit intestinal metaplasia progression
by: Xiangming Huang, et al.
Published: (2024)
by: Xiangming Huang, et al.
Published: (2024)
Correction to: Sclareol attenuates angiotensin II‐induced cardiac remodeling and inflammation via inhibiting MAPK signaling
by: Na Yang, et al.
Published: (2024)
by: Na Yang, et al.
Published: (2024)
Ginkgo Flavone Aglycone Ameliorates Atherosclerosis via Inhibiting Endothelial Pyroptosis by Activating the Nrf2 Pathway
by: Xingyi Chen, et al.
Published: (2024)
by: Xingyi Chen, et al.
Published: (2024)
Magnoflorine alleviates dextran sulfate sodium‐induced ulcerative colitis via inhibiting JAK2/STAT3 signaling pathway
by: Jianxia Wen, et al.
Published: (2024)
by: Jianxia Wen, et al.
Published: (2024)
Erucin Alleviates Cardiac Hypertrophy by Improving Mitochondrial Function via Nrf2‐Sirt3 Pathway
by: Shushu Jiang, et al.
Published: (2025)
by: Shushu Jiang, et al.
Published: (2025)
Kaempferitrin attenuates unilateral ureteral obstruction‐induced renal inflammation and fibrosis in mice by inhibiting NOX4‐mediated tubular ferroptosis
by: Jianchun Li, et al.
Published: (2024)
by: Jianchun Li, et al.
Published: (2024)
Crocin Attenuates Nrf2/ GPX4 Mediated Ferroptosis in Obstructive Nephropathy by Selectively Targeting MKK4
by: Ziyun Xu, et al.
Published: (2025)
by: Ziyun Xu, et al.
Published: (2025)
Neuroinflammation inhibition and neuroprotective effects of purpurin, a potential anti‐AD compound, screened via network proximity and gene enrichment analyses
by: Jun Zhao, et al.
Published: (2024)
by: Jun Zhao, et al.
Published: (2024)
Geniposidic Acid Attenuates Chronic Tubulointerstitial Nephropathy Through Regulation of the NF‐ƙB/Nrf2 Pathway Via Aryl Hydrocarbon Receptor Signaling
by: Yan‐Ni Wang, et al.
Published: (2024)
by: Yan‐Ni Wang, et al.
Published: (2024)
Astragalin Inhibits Oxidative Stress‐Induced Pyroptosis and Apoptosis in Mouse Models of Renal Ischemia/Reperfusion Injury by Activating the SIRT1 /Nrf2 Pathway
by: Qian Huang, et al.
Published: (2025)
by: Qian Huang, et al.
Published: (2025)
Total astragalus saponins attenuate primary sclerosing cholangitis in mice by upregulation of TGR5
by: Qun Zhou, et al.
Published: (2024)
by: Qun Zhou, et al.
Published: (2024)
Paeoniflorin Ameliorates Alcohol‐Induced Depression via Modulating the Gut–Brain Axis and Inhibiting the NF ‐ κB / NLRP3 Inflammasome Pathway in Mice
by: Jingwei Yu, et al.
Published: (2026)
by: Jingwei Yu, et al.
Published: (2026)
The Role of NLRP3 Inflammasomes in Neurological Disorders: Mechanistic Understanding and Phytochemical‐Based Therapeutics
by: Saloni Rahi, et al.
Published: (2026)
by: Saloni Rahi, et al.
Published: (2026)
Nrf2‐Mediated Ferroptosis Is Involved in Berberine‐Induced Alleviation of Diabetic Kidney Disease
by: Kun Gao, et al.
Published: (2025)
by: Kun Gao, et al.
Published: (2025)
Targeting the NLRP3 Inflammasome in Atherosclerosis: Advances in Anti‐Inflammatory Therapies With Bioactive Natural Products
by: Haizhen Guo, et al.
Published: (2026)
by: Haizhen Guo, et al.
Published: (2026)
Betulin Protects Against Cardiac Hypertrophy by Improving AMPK /Nrf2‐Dependent Mitochondrial Function
by: Bei Zheng, et al.
Published: (2026)
by: Bei Zheng, et al.
Published: (2026)
Pogostone Suppresses Microglial NLRP3 Inflammasome Activation‐Promoted Remyelination Through RXRγ Regulation of Mitophagy
by: Menghan Qian, et al.
Published: (2026)
by: Menghan Qian, et al.
Published: (2026)
Similar Items
-
Cucurbitacin B modulates M2 macrophage differentiation and attenuates osteosarcoma progression via PI3K/AKT pathway
by: Hong Wu, et al.
Published: (2024) -
20(R)‐ginsenoside Rg3 attenuates cerebral ischemia–reperfusion injury by mitigating mitochondrial oxidative stress via the Nrf2/HO‐1 signaling pathway
by: Deyun Chen, et al.
Published: (2024) -
Mechanism of Cucurbitacin B Targeting ZNF70 / NLRP3 Axis Against Inflammation‐Associated Colorectal Cancer
by: Shen Cao, et al.
Published: (2026) -
Dihydroartemisinin‐driven TOM70 inhibition leads to mitochondrial destabilization to induce pyroptosis against lung cancer
by: Liu‐Gen Li, et al.
Published: (2024) -
Mitochondrial‐targeted curcumin inhibits T‐cell activation via Nrf2 and inhibits graft‐versus‐host‐disease in a mouse model
by: Raghavendra S. Patwardhan, et al.
Published: (2024)