Buchumschlag

Dihydroartemisinin‐driven TOM70 inhibition leads to mitochondrial destabilization to induce pyroptosis against lung cancer

Fuente: Wiley Open Access

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	Liu‐Gen Li, Jun Hu, Ning Han, Nan‐Nan Chen, Ting‐Ting Yu, Tao Ren, Hua‐Zhen Xu, Xing‐Chun Peng, Xian‐Yu Li, Tian‐Qi Ma, Hao Chen, Lei Zhang, Xiao Chen, Mei‐Fang Wang, Tong‐Fei Li
Format:	Artículo Open Access
Veröffentlicht:	Wiley 2024
Schlagworte:	Phytotherapy Research
Online-Zugang:	Acceder al recurso
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge

Cucurbitacin B attenuates osteoarthritis development by inhibiting NLRP3 inflammasome activation and pyroptosis through activating Nrf2/HO‐1 pathway
von: Chao Lou, et al.
Veröffentlicht: (2024)

Celastrol Targets Hsc70‐Bim Interaction as a Novel Senolytic to Extend Lifespan and Mitigate Organ Fibrosis
von: Weitong Xu, et al.
Veröffentlicht: (2026)

Oleandrin enhances radiotherapy sensitivity in lung cancer by inhibiting the ATM/ATR‐mediated DNA damage response
von: Qiong Wu, et al.
Veröffentlicht: (2024)

Harringtonine Elicits Ferroptosis by Regulating SYVN1 ‐Mediated FASN Ubiquitination for Evoking Anti‐Lung Cancer Efficacy
von: Ning Han, et al.
Veröffentlicht: (2025)

D‐pinitol alleviates diabetic cardiomyopathy by inhibiting the optineurin‐mediated endoplasmic reticulum stress and glycophagy signaling pathway
von: Xiaoli Li, et al.
Veröffentlicht: (2024)

Pterostilbene Exhibits Broad‐Spectrum Antiviral Activity by Targeting the Enterovirus Capsid, Inactivating Viral Particles, Blocking Viral Binding, and Protecting Mice From Lethal EV‐A71 Challenge
von: Kuan‐Ting Chuang, et al.
Veröffentlicht: (2025)

Kaempferitrin attenuates unilateral ureteral obstruction‐induced renal inflammation and fibrosis in mice by inhibiting NOX4‐mediated tubular ferroptosis
von: Jianchun Li, et al.
Veröffentlicht: (2024)

Hesperetin promotes diabetic wound healing by inhibiting ferroptosis through the activation of SIRT3
von: Xianbin Yu, et al.
Veröffentlicht: (2024)

Resveratrol triggers autophagy‐related apoptosis to inhibit the progression of colorectal cancer via inhibition of FOXQ1
von: MinFeng Zhou, et al.
Veröffentlicht: (2024)

Costunolide Ameliorates Hepatic Steatosis and Insulin Resistance in a Diet‐Induced Mouse Model of Metabolic Dysfunction‐Associated Steatotic Liver Disease by Activating the AMPK / ACC1 Signalling Pathway
von: Wen Jiang, et al.
Veröffentlicht: (2026)

Asiaticoside ameliorates DSS‐induced colitis in mice by inhibiting inflammatory response, protecting intestinal barrier and regulating intestinal microecology
von: Kunjian Liu, et al.
Veröffentlicht: (2024)

Salvianolic acid B alleviates autoimmunity in Treg‐deficient mice via inhibiting IL2‐STAT5 signaling
von: Ting Wang, et al.
Veröffentlicht: (2024)

Diallyl disulfide, the bioactive component of Allium species, ameliorates pulmonary fibrosis by mediating the crosstalk of farnesoid X receptor and yes‐associated protein 1 signaling pathway
von: Jia‐yi Dou, et al.
Veröffentlicht: (2024)

Isoalantolactone exerts anti‐melanoma effects via inhibiting PI3K/AKT/mTOR and STAT3 signaling in cell and mouse models
von: Jun‐Kui Li, et al.
Veröffentlicht: (2024)

Effects of Ginseng Consumption on Cardiovascular Health Biomarkers in Adults: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials
von: Xiao‐Feng Zhang, et al.
Veröffentlicht: (2024)

Regulation of mitophagy and mitochondrial function: Natural compounds as potential therapeutic strategies for Parkinson's disease
von: Hao Liang, et al.
Veröffentlicht: (2024)

Promising natural products targeting protein tyrosine phosphatase SHP2 for cancer therapy
von: Jiani Lu, et al.
Veröffentlicht: (2024)

Geniposide modulates GSK3β to inhibit Th17 differentiation and mitigate endothelial damage in intracranial aneurysm
von: Qian Zhang, et al.
Veröffentlicht: (2024)

Preprotective Effects of Cardamomin From Amomum villosum Lour. on H 2 O 2 ‐Induced Oxidative Damage In Vitro and Cerebral Ischemic Stroke In Vivo
von: Man Zhu, et al.
Veröffentlicht: (2025)

Naringenin inhibits the microsomal triglyceridetransfer protein/apolipoprotein B axis to inhibit intestinal metaplasia progression
von: Xiangming Huang, et al.
Veröffentlicht: (2024)

Recent Advances in the Anti‐Obesity Benefits of Phytoconstituents: From Phytochemistry to Targeting Novel‐Systems
von: Jing Xian, et al.
Veröffentlicht: (2024)

Toosendanin Induces Cell Cycle Arrest and Apoptosis to Suppress Diffuse Large B‐Cell Lymphoma Growth by Inhibiting PI3Kα/β and PLK1 Signaling
von: Qian Hu, et al.
Veröffentlicht: (2025)

Plantaginis Semen, a Novel Natural S1PR1 Agonist, Inhibits Oxidative Stress and Inflammation to Treat Lipopolysaccharide‐Induced Acute Lung Injury
von: WanAi Xu, et al.
Veröffentlicht: (2025)

Panax ginseng C. A. Mey. Targeting Pyroptosis for Treatment of Diabetes Related Metabolic Diseases: A Review of Potential Therapeutic Strategies
von: Meng Sun, et al.
Veröffentlicht: (2025)

Magnoflorine alleviates dextran sulfate sodium‐induced ulcerative colitis via inhibiting JAK2/STAT3 signaling pathway
von: Jianxia Wen, et al.
Veröffentlicht: (2024)

Effect and mechanism of quercetin or quercetin‐containing formulas against COVID‐19: From bench to bedside
von: Jhong Yuan Chen, et al.
Veröffentlicht: (2024)

Curculigoside, a traditional Chinese medicine monomer, ameliorates oxidative stress in Alzheimer's disease mouse model via suppressing ferroptosis
von: Yuhang Gong, et al.
Veröffentlicht: (2024)

Scutellarein alleviates osteoarthritis progression through the PI3K/Akt/NF‐kappaB signaling pathway: In vitro and in vivo studies
von: Ziyang Ye, et al.
Veröffentlicht: (2024)

20(R)‐ginsenoside Rg3 attenuates cerebral ischemia–reperfusion injury by mitigating mitochondrial oxidative stress via the Nrf2/HO‐1 signaling pathway
von: Deyun Chen, et al.
Veröffentlicht: (2024)

Salidroside directly activates HSC70, revealing a new role for HSC70 in BDNF signalling and neurogenesis after cerebral ischemia
von: Wenfang Lai, et al.
Veröffentlicht: (2024)

Morroniside Modulates Microglia Polarization via the CX3CL1/CX3CR1/PU.1 Axis in ApoE4 Transgenic Mice
von: Ying‐Yan Chang, et al.
Veröffentlicht: (2026)

Advances in Research on Marine Natural Products for Modulating the Inflammatory Microenvironment
von: Yuru Li, et al.
Veröffentlicht: (2025)

Pomegranate polyphenol punicalin ameliorates lipopolysaccharide‐induced memory impairment, behavioral disorders, oxidative stress, and neuroinflammation via inhibition of TLR4‐NF‐кB pathway
von: Peng Chen, et al.
Veröffentlicht: (2024)

The combination of berberine and isoliquiritigenin synergistically improved adipose inflammation and obesity‐induced insulin resistance
von: Xiao‐Yu Zhang, et al.
Veröffentlicht: (2024)

Trifolirhizin reduces osteoclast formation and prevents inflammatory osteolysis by inhibiting RANKL‐induced activation of NF‐κB and MAPK signaling pathways and ROS
von: Jian Huang, et al.
Veröffentlicht: (2024)

Polydatin Targets ACADVL to Combat Obesity by Promoting Adipocyte Browning and Activating Fatty Acid Oxidation
von: Wenjun He, et al.
Veröffentlicht: (2026)

Notoginsenoside R1 , a Novel Natural PPARγ Agonist, Attenuates Cognitive Deficits in a Mouse Model of Diabetic Alzheimer's Disease Through Enhancing GLUT4 ‐Dependent Neuronal Glucose Uptake
von: Zongyang Li, et al.
Veröffentlicht: (2025)

Genistein Ameliorates the Ischemic State of Random Skin Flap by Regulating Macrophage Polarization Through AMPK / SIRT1 Signaling Pathway
von: Yuedong Fu, et al.
Veröffentlicht: (2025)

Research Progress on the Role of Natural Active Substances in Regulating Adenosine Pathway in Tumor Therapy
von: Xinyu Yang, et al.
Veröffentlicht: (2026)

Curcumin Nanoparticle Induces Apoptosis in Colon Cancer Cells via ROS ‐Mediated AMPK / mTOR / ULK1 Autophagy Pathway
von: Bingqing Liang, et al.
Veröffentlicht: (2025)