Recent Advances in the Anti‐Obesity Benefits of Phytoconstituents: From Phytochemistry to Targeting Novel‐Systems

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Autori principali: Jing Xian, Yu Huang, Jinrong Bai, Qian Liao, Qiyan Chen, Weijian Cheng, Ziye Su, Siyao Li, Yihan Wu, Jingjing Li, Jinming Zhang
Natura: Artículo Open Access
Pubblicazione: Wiley 2024
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author Jing Xian
Yu Huang
Jinrong Bai
Qian Liao
Qiyan Chen
Weijian Cheng
Ziye Su
Siyao Li
Yihan Wu
Jingjing Li
Jinming Zhang
author_facet Jing Xian
Yu Huang
Jinrong Bai
Qian Liao
Qiyan Chen
Weijian Cheng
Ziye Su
Siyao Li
Yihan Wu
Jingjing Li
Jinming Zhang
Jing Xian
Yu Huang
Jinrong Bai
Qian Liao
Qiyan Chen
Weijian Cheng
Ziye Su
Siyao Li
Yihan Wu
Jingjing Li
Jinming Zhang
collection Wiley Open Access
contents Recent Advances in the Anti‐Obesity Benefits of Phytoconstituents: From Phytochemistry to Targeting Novel‐Systems Jing Xian Yu Huang Jinrong Bai Qian Liao Qiyan Chen Weijian Cheng Ziye Su Siyao Li Yihan Wu Jingjing Li Jinming Zhang Phytotherapy Research ABSTRACT Obesity is a metabolic disorder that has become a global health concern. The existing pharmaceutical drugs for treating obesity have some side effects. Compounds from natural sources are prospective substitutes for treating chronic diseases such as obesity, with the added advantages of being safe and cost‐effective. However, due to factors such as poor solubility, low bioavailability, and instability in the physiological environment, the therapeutic efficacy of phytoconstituents is limited. Nowadays, developing nanoscaled systems has emerged as a vital strategy for enhancing the delivery and therapeutic effect of phytoconstituents. The present study discusses and categorizes phytoconstituents with anti‐obesity effects and concludes the main mechanisms underlying their effects. Importantly, strategies used to develop phytoconstituent‐based nano‐drug delivery systems (NDDS) for obesity treatment that show improved efficacy relative to traditional administration routes are reviewed. Finally, the progress of research on phytoconstituent‐based NDDS for obesity treatment is summarized to provide a reference for the development of safe and effective treatment strategies for obesity. 10.1002/ptr.8400 http://onlinelibrary.wiley.com/termsAndConditions#vor
doi_str_mv 10.1002/ptr.8400
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institution Wiley Open Access
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publishDate 2024
publisher Wiley
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spellingShingle Recent Advances in the Anti‐Obesity Benefits of Phytoconstituents: From Phytochemistry to Targeting Novel‐Systems
Jing Xian
Yu Huang
Jinrong Bai
Qian Liao
Qiyan Chen
Weijian Cheng
Ziye Su
Siyao Li
Yihan Wu
Jingjing Li
Jinming Zhang
Phytotherapy Research
Recent Advances in the Anti‐Obesity Benefits of Phytoconstituents: From Phytochemistry to Targeting Novel‐Systems Jing Xian Yu Huang Jinrong Bai Qian Liao Qiyan Chen Weijian Cheng Ziye Su Siyao Li Yihan Wu Jingjing Li Jinming Zhang Phytotherapy Research ABSTRACT Obesity is a metabolic disorder that has become a global health concern. The existing pharmaceutical drugs for treating obesity have some side effects. Compounds from natural sources are prospective substitutes for treating chronic diseases such as obesity, with the added advantages of being safe and cost‐effective. However, due to factors such as poor solubility, low bioavailability, and instability in the physiological environment, the therapeutic efficacy of phytoconstituents is limited. Nowadays, developing nanoscaled systems has emerged as a vital strategy for enhancing the delivery and therapeutic effect of phytoconstituents. The present study discusses and categorizes phytoconstituents with anti‐obesity effects and concludes the main mechanisms underlying their effects. Importantly, strategies used to develop phytoconstituent‐based nano‐drug delivery systems (NDDS) for obesity treatment that show improved efficacy relative to traditional administration routes are reviewed. Finally, the progress of research on phytoconstituent‐based NDDS for obesity treatment is summarized to provide a reference for the development of safe and effective treatment strategies for obesity. 10.1002/ptr.8400 http://onlinelibrary.wiley.com/termsAndConditions#vor
title Recent Advances in the Anti‐Obesity Benefits of Phytoconstituents: From Phytochemistry to Targeting Novel‐Systems
topic Phytotherapy Research
url https://onlinelibrary.wiley.com/doi/10.1002/ptr.8400