Chinese Herbal Medicine and Their Active Ingredients Involved in the Treatment of Atopic Dermatitis Related Signaling Pathways

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Main Authors: Wenkai Nie, Hao Fu, Yan Zhang, Huiwen Yang, Bing Liu
Format: Artículo Open Access
Published: Wiley 2025
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author Wenkai Nie
Hao Fu
Yan Zhang
Huiwen Yang
Bing Liu
author_facet Wenkai Nie
Hao Fu
Yan Zhang
Huiwen Yang
Bing Liu
Wenkai Nie
Hao Fu
Yan Zhang
Huiwen Yang
Bing Liu
collection Wiley Open Access
contents Chinese Herbal Medicine and Their Active Ingredients Involved in the Treatment of Atopic Dermatitis Related Signaling Pathways Wenkai Nie Hao Fu Yan Zhang Huiwen Yang Bing Liu Phytotherapy Research ABSTRACT Atopic dermatitis (AD) is a common inflammatory dermatitis of the skin and poses therapeutic challenges due to the adverse reactions and high costs associated with available treatments. In Eastern Asian countries, a plethora of herbal remedies is extensively employed for the alleviation of AD. Many of these botanicals are renowned for their formidable anti‐inflammatory properties, contributing to AD management. Chinese herbal medicine (CHM) and its active ingredients exhibit both prophylactic and therapeutic promise against AD by modulating inflammatory response, orchestrating immune system functions, and enhancing antioxidant activities. A comprehensive exploration of the underlying mechanisms involved in CHM treatment can enhance the comprehension of AD pathogenesis and facilitate the development of innovative drugs for AD. This study aims to elucidate the signaling pathways and potential targets implicated in CHM‐based treatment of AD, providing a systematic theoretical framework for its application in therapy while serving as a valuable reference for developing more effective and safer AD therapeutic agents. 10.1002/ptr.8409 http://onlinelibrary.wiley.com/termsAndConditions#vor
doi_str_mv 10.1002/ptr.8409
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institution Wiley Open Access
license_str_mv http://onlinelibrary.wiley.com/termsAndConditions#vor
publishDate 2025
publisher Wiley
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spellingShingle Chinese Herbal Medicine and Their Active Ingredients Involved in the Treatment of Atopic Dermatitis Related Signaling Pathways
Wenkai Nie
Hao Fu
Yan Zhang
Huiwen Yang
Bing Liu
Phytotherapy Research
Chinese Herbal Medicine and Their Active Ingredients Involved in the Treatment of Atopic Dermatitis Related Signaling Pathways Wenkai Nie Hao Fu Yan Zhang Huiwen Yang Bing Liu Phytotherapy Research ABSTRACT Atopic dermatitis (AD) is a common inflammatory dermatitis of the skin and poses therapeutic challenges due to the adverse reactions and high costs associated with available treatments. In Eastern Asian countries, a plethora of herbal remedies is extensively employed for the alleviation of AD. Many of these botanicals are renowned for their formidable anti‐inflammatory properties, contributing to AD management. Chinese herbal medicine (CHM) and its active ingredients exhibit both prophylactic and therapeutic promise against AD by modulating inflammatory response, orchestrating immune system functions, and enhancing antioxidant activities. A comprehensive exploration of the underlying mechanisms involved in CHM treatment can enhance the comprehension of AD pathogenesis and facilitate the development of innovative drugs for AD. This study aims to elucidate the signaling pathways and potential targets implicated in CHM‐based treatment of AD, providing a systematic theoretical framework for its application in therapy while serving as a valuable reference for developing more effective and safer AD therapeutic agents. 10.1002/ptr.8409 http://onlinelibrary.wiley.com/termsAndConditions#vor
title Chinese Herbal Medicine and Their Active Ingredients Involved in the Treatment of Atopic Dermatitis Related Signaling Pathways
topic Phytotherapy Research
url https://onlinelibrary.wiley.com/doi/10.1002/ptr.8409