Utilising biosensor‐based approaches for identifying neurotropic viruses

Fuente: Wiley Open Access
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Autori principali: Mohammed Alissa, Ahmed Hjazi
Natura: Artículo Open Access
Pubblicazione: Wiley 2024
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author Mohammed Alissa
Ahmed Hjazi
author_facet Mohammed Alissa
Ahmed Hjazi
Mohammed Alissa
Ahmed Hjazi
collection Wiley Open Access
contents Utilising biosensor‐based approaches for identifying neurotropic viruses Mohammed Alissa Ahmed Hjazi Reviews in Medical Virology AbstractNeurotropic viruses, with their ability to invade the central nervous system, present a significant public health challenge, causing a spectrum of neurological diseases. Clinical manifestations of neurotropic viral infections vary widely, from mild to life‐threatening conditions, such as HSV‐induced encephalitis or poliovirus‐induced poliomyelitis. Traditional diagnostic methods, including polymerase chain reaction, serological assays, and imaging techniques, though valuable, have limitations. To address these challenges, biosensor‐based methods have emerged as a promising approach. These methods offer advantages such as rapid results, high sensitivity, specificity, and potential for point‐of‐care applications. By targeting specific biomarkers or genetic material, biosensors utilise technologies like surface plasmon resonance and microarrays, providing a direct and efficient means of diagnosing neurotropic infections. This review explores the evolving landscape of biosensor‐based methods, highlighting their potential to enhance the diagnostic toolkit for neurotropic viruses. 10.1002/rmv.2513 http://onlinelibrary.wiley.com/termsAndConditions#vor
doi_str_mv 10.1002/rmv.2513
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institution Wiley Open Access
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spellingShingle Utilising biosensor‐based approaches for identifying neurotropic viruses
Mohammed Alissa
Ahmed Hjazi
Reviews in Medical Virology
Utilising biosensor‐based approaches for identifying neurotropic viruses Mohammed Alissa Ahmed Hjazi Reviews in Medical Virology AbstractNeurotropic viruses, with their ability to invade the central nervous system, present a significant public health challenge, causing a spectrum of neurological diseases. Clinical manifestations of neurotropic viral infections vary widely, from mild to life‐threatening conditions, such as HSV‐induced encephalitis or poliovirus‐induced poliomyelitis. Traditional diagnostic methods, including polymerase chain reaction, serological assays, and imaging techniques, though valuable, have limitations. To address these challenges, biosensor‐based methods have emerged as a promising approach. These methods offer advantages such as rapid results, high sensitivity, specificity, and potential for point‐of‐care applications. By targeting specific biomarkers or genetic material, biosensors utilise technologies like surface plasmon resonance and microarrays, providing a direct and efficient means of diagnosing neurotropic infections. This review explores the evolving landscape of biosensor‐based methods, highlighting their potential to enhance the diagnostic toolkit for neurotropic viruses. 10.1002/rmv.2513 http://onlinelibrary.wiley.com/termsAndConditions#vor
title Utilising biosensor‐based approaches for identifying neurotropic viruses
topic Reviews in Medical Virology
url https://onlinelibrary.wiley.com/doi/10.1002/rmv.2513