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Main Authors: Erica M. Porter, Christopher T. Franck, Stephen Adams
Format: Artículo Open Access
Published: Wiley 2024
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Online Access:https://onlinelibrary.wiley.com/doi/10.1002/sim.10113
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author Erica M. Porter
Christopher T. Franck
Stephen Adams
author_facet Erica M. Porter
Christopher T. Franck
Stephen Adams
Erica M. Porter
Christopher T. Franck
Stephen Adams
collection Wiley Open Access
contents Flexible cost‐penalized Bayesian model selection: Developing inclusion paths with an application to diagnosis of heart disease Erica M. Porter Christopher T. Franck Stephen Adams Statistics in Medicine We propose a Bayesian model selection approach that allows medical practitioners to select among predictor variables while taking their respective costs into account. Medical procedures almost always incur costs in time and/or money. These costs might exceed their usefulness for modeling the outcome of interest. We develop Bayesian model selection that uses flexible model priors to penalize costly predictors a priori and select a subset of predictors useful relative to their costs. Our approach (i) gives the practitioner control over the magnitude of cost penalization, (ii) enables the prior to scale well with sample size, and (iii) enables the creation of our proposed inclusion path visualization, which can be used to make decisions about individual candidate predictors using both probabilistic and visual tools. We demonstrate the effectiveness of our inclusion path approach and the importance of being able to adjust the magnitude of the prior's cost penalization through a dataset pertaining to heart disease diagnosis in patients at the Cleveland Clinic Foundation, where several candidate predictors with various costs were recorded for patients, and through simulated data. 10.1002/sim.10113 http://creativecommons.org/licenses/by/4.0/
doi_str_mv 10.1002/sim.10113
format Artículo Open Access
id wiley_oa_10_1002_sim_10113
institution Wiley Open Access
license_str_mv http://creativecommons.org/licenses/by/4.0/
publishDate 2024
publisher Wiley
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spellingShingle Flexible cost‐penalized Bayesian model selection: Developing inclusion paths with an application to diagnosis of heart disease
Erica M. Porter
Christopher T. Franck
Stephen Adams
Statistics in Medicine
Flexible cost‐penalized Bayesian model selection: Developing inclusion paths with an application to diagnosis of heart disease Erica M. Porter Christopher T. Franck Stephen Adams Statistics in Medicine We propose a Bayesian model selection approach that allows medical practitioners to select among predictor variables while taking their respective costs into account. Medical procedures almost always incur costs in time and/or money. These costs might exceed their usefulness for modeling the outcome of interest. We develop Bayesian model selection that uses flexible model priors to penalize costly predictors a priori and select a subset of predictors useful relative to their costs. Our approach (i) gives the practitioner control over the magnitude of cost penalization, (ii) enables the prior to scale well with sample size, and (iii) enables the creation of our proposed inclusion path visualization, which can be used to make decisions about individual candidate predictors using both probabilistic and visual tools. We demonstrate the effectiveness of our inclusion path approach and the importance of being able to adjust the magnitude of the prior's cost penalization through a dataset pertaining to heart disease diagnosis in patients at the Cleveland Clinic Foundation, where several candidate predictors with various costs were recorded for patients, and through simulated data. 10.1002/sim.10113 http://creativecommons.org/licenses/by/4.0/
title Flexible cost‐penalized Bayesian model selection: Developing inclusion paths with an application to diagnosis of heart disease
topic Statistics in Medicine
url https://onlinelibrary.wiley.com/doi/10.1002/sim.10113