Nothing to See Here? A Non‐Inferiority Approach to Parallel Trends

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Hauptverfasser: Alyssa Bilinski, Laura A. Hatfield
Format: Artículo Open Access
Veröffentlicht: Wiley 2026
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author Alyssa Bilinski
Laura A. Hatfield
author_facet Alyssa Bilinski
Laura A. Hatfield
Alyssa Bilinski
Laura A. Hatfield
collection Wiley Open Access
contents Nothing to See Here? A Non‐Inferiority Approach to Parallel Trends Alyssa Bilinski Laura A. Hatfield Statistics in Medicine ABSTRACT Difference‐in‐differences is a popular method for observational health policy evaluation. It relies on a causal assumption that in the absence of intervention, treatment groups' outcomes would have evolved in parallel to those of comparison groups. Researchers frequently look for parallel trends in the pre‐intervention period to bolster confidence in this assumption. The popular “parallel trends test” evaluates a null hypothesis of parallel trends and, failing to find evidence against the null, concludes that the assumption holds. This tightly controls the probability of falsely concluding that trends are not parallel, but may have low power to detect non‐parallel trends. When used as a screening step, it can also introduce bias in treatment effect estimates. We propose a non‐inferiority/equivalence approach that tightly controls the probability of missing large violations of parallel trends, measured on the scale of the treatment effect. Our framework nests several common use cases, including linear trend tests and event studies. We show that our approach may induce no or minimal bias when used as a screening step under commonly assumed error structures and, absent violations, can offer a higher‐power alternative to testing treatment effects in more flexible models. We illustrate our ideas by reconsidering a study of the impact of the Affordable Care Act's dependent coverage provision. 10.1002/sim.70296 http://onlinelibrary.wiley.com/termsAndConditions#vor
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spellingShingle Nothing to See Here? A Non‐Inferiority Approach to Parallel Trends
Alyssa Bilinski
Laura A. Hatfield
Statistics in Medicine
Nothing to See Here? A Non‐Inferiority Approach to Parallel Trends Alyssa Bilinski Laura A. Hatfield Statistics in Medicine ABSTRACT Difference‐in‐differences is a popular method for observational health policy evaluation. It relies on a causal assumption that in the absence of intervention, treatment groups' outcomes would have evolved in parallel to those of comparison groups. Researchers frequently look for parallel trends in the pre‐intervention period to bolster confidence in this assumption. The popular “parallel trends test” evaluates a null hypothesis of parallel trends and, failing to find evidence against the null, concludes that the assumption holds. This tightly controls the probability of falsely concluding that trends are not parallel, but may have low power to detect non‐parallel trends. When used as a screening step, it can also introduce bias in treatment effect estimates. We propose a non‐inferiority/equivalence approach that tightly controls the probability of missing large violations of parallel trends, measured on the scale of the treatment effect. Our framework nests several common use cases, including linear trend tests and event studies. We show that our approach may induce no or minimal bias when used as a screening step under commonly assumed error structures and, absent violations, can offer a higher‐power alternative to testing treatment effects in more flexible models. We illustrate our ideas by reconsidering a study of the impact of the Affordable Care Act's dependent coverage provision. 10.1002/sim.70296 http://onlinelibrary.wiley.com/termsAndConditions#vor
title Nothing to See Here? A Non‐Inferiority Approach to Parallel Trends
topic Statistics in Medicine
url https://onlinelibrary.wiley.com/doi/10.1002/sim.70296