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| Main Authors: | , , , , , , , |
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| Format: | Artículo Open Access |
| Published: |
Wiley
2025
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| Subjects: | |
| Online Access: | https://onlinelibrary.wiley.com/doi/10.1111/aej.70013 |
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Table of Contents:
- In Vitro Assessment of the Effects of Endodontic Sealers on Cell Viability, Adhesion, and Migration Anna Carolina Neves Leutz Victor Augusto Benedicto dos Santos Ana Cristina Padilha Janini Amanda Nowicki de Salles Brenda Paula Figueiredo de Almeida Gomes Adriana de Jesus Soares Talita Tartari Marina Angélica Marciano Australian Endodontic Journal ABSTRACT This study aimed to evaluate the in vitro cytocompatibility and bioactivity of the newly launched calcium silicate‐based sealer BioRoot Flow, compared with other calcium silicate‐based sealers (AH Plus Bioceramic Sealer and BioRoot RCS) and the epoxy resin‐based AH Plus Jet. NIH/3 T3 fibroblasts were used to assess cell viability, adhesion, and migration. Material characterisation was performed using SEM, EDS, and XRD. BioRoot RCS exhibited the highest cell viability, while BioRoot Flow showed fewer adherent cells and reduced migration at 72 h. EDS revealed zirconium content in BioRoot Flow, and XRD confirmed calcite presence in all calcium silicate‐based sealers. Variations in cell behaviour may be related to differences in chemical composition and surface properties, highlighting the need for further investigation. 10.1111/aej.70013 http://creativecommons.org/licenses/by/4.0/