Sex differences among patients with intentional poisoning presenting to the emergency Department at a Tertiary Care Centre in Beirut, Lebanon
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2024
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| author | Tharwat El Zahran Lina Hammoud Rana Salam Youssef Salam Ziad Kazzi Hani Tamim Eveline Hitti |
| author_facet | Tharwat El Zahran Lina Hammoud Rana Salam Youssef Salam Ziad Kazzi Hani Tamim Eveline Hitti Tharwat El Zahran Lina Hammoud Rana Salam Youssef Salam Ziad Kazzi Hani Tamim Eveline Hitti |
| collection | Wiley Open Access |
| contents | Sex differences among patients with intentional poisoning presenting to the emergency Department at a Tertiary Care Centre in Beirut, Lebanon Tharwat El Zahran Lina Hammoud Rana Salam Youssef Salam Ziad Kazzi Hani Tamim Eveline Hitti Basic & Clinical Pharmacology & Toxicology AbstractPoisoning poses a worldwide public health challenge and recent data from Lebanon in 2020 revealed that over half patients presenting with acute toxicological exposure intentionally poisoned themselves, primarily with suspected suicidal intent. This study aims to assess sex disparities in intentional toxicological exposures among patients presenting to the Emergency Department, at a tertiary care centre in Lebanon. This was a secondary analysis of an existing toxicological database, including patients aged 6 years and older admitted due to acute overdose from March 2015 to August 2022. A total of 444 cases of intentional poisoning were analysed, with 302 (68.0%) women. The primary cause of intentional poisoning was suspected suicide in both sexes, significantly more common in women (85.1%versus65.5%,P < 0.001). Specific agents exposed to patients varied by sex; sedatives/hypnotics/antipsychotics, antihistamines, and melitracen/flupentixol were significantly more prevalent in women (P < 0.001) while men showed higher prevalence for ethanol (P = 0.02), stimulants, street drugs and opioids (P < 0.001). Our study underscores substantial sex differences in intentional poisoning cases in Lebanon. Women exhibited a higher likelihood of exposures to sedatives/hypnotics/antipsychotics, antihistamines and melitracen/flupentixol, while stimulant drugs, ethanol, and opioids were prevalent in men. Developing proper and effective sex‐specific measures may mitigate potential physical and psychological consequences. 10.1111/bcpt.14039 http://onlinelibrary.wiley.com/termsAndConditions#vor |
| doi_str_mv | 10.1111/bcpt.14039 |
| format | Artículo Open Access |
| id | wiley_oa_10_1111_bcpt_14039 |
| institution | Wiley Open Access |
| license_str_mv | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| publishDate | 2024 |
| publisher | Wiley |
| record_format | wiley_oa |
| spellingShingle | Sex differences among patients with intentional poisoning presenting to the emergency Department at a Tertiary Care Centre in Beirut, Lebanon Tharwat El Zahran Lina Hammoud Rana Salam Youssef Salam Ziad Kazzi Hani Tamim Eveline Hitti Basic & Clinical Pharmacology & Toxicology Sex differences among patients with intentional poisoning presenting to the emergency Department at a Tertiary Care Centre in Beirut, Lebanon Tharwat El Zahran Lina Hammoud Rana Salam Youssef Salam Ziad Kazzi Hani Tamim Eveline Hitti Basic & Clinical Pharmacology & Toxicology AbstractPoisoning poses a worldwide public health challenge and recent data from Lebanon in 2020 revealed that over half patients presenting with acute toxicological exposure intentionally poisoned themselves, primarily with suspected suicidal intent. This study aims to assess sex disparities in intentional toxicological exposures among patients presenting to the Emergency Department, at a tertiary care centre in Lebanon. This was a secondary analysis of an existing toxicological database, including patients aged 6 years and older admitted due to acute overdose from March 2015 to August 2022. A total of 444 cases of intentional poisoning were analysed, with 302 (68.0%) women. The primary cause of intentional poisoning was suspected suicide in both sexes, significantly more common in women (85.1%versus65.5%,P < 0.001). Specific agents exposed to patients varied by sex; sedatives/hypnotics/antipsychotics, antihistamines, and melitracen/flupentixol were significantly more prevalent in women (P < 0.001) while men showed higher prevalence for ethanol (P = 0.02), stimulants, street drugs and opioids (P < 0.001). Our study underscores substantial sex differences in intentional poisoning cases in Lebanon. Women exhibited a higher likelihood of exposures to sedatives/hypnotics/antipsychotics, antihistamines and melitracen/flupentixol, while stimulant drugs, ethanol, and opioids were prevalent in men. Developing proper and effective sex‐specific measures may mitigate potential physical and psychological consequences. 10.1111/bcpt.14039 http://onlinelibrary.wiley.com/termsAndConditions#vor |
| title | Sex differences among patients with intentional poisoning presenting to the emergency Department at a Tertiary Care Centre in Beirut, Lebanon |
| topic | Basic & Clinical Pharmacology & Toxicology |
| url | https://onlinelibrary.wiley.com/doi/10.1111/bcpt.14039 |