Cover Image

Neuroprotective amyloid β N‐terminal peptides differentially alter human α7‐ and α7β2‐nicotinic acetylcholine (nACh) receptor single‐channel properties

Fuente: Wiley Open Access

Saved in:

Bibliographic Details
Main Authors:	Catherine F. Roberts, Yiwei Cao, Wonpil Im, Robert A. Nichols, Ronald J. Lukas, Andrew A. George
Format:	Artículo Open Access
Published:	Wiley 2024
Subjects:	British Journal of Pharmacology
Online Access:	Acceder al recurso
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Correction to “Hippocampal α7 nicotinic ACh receptors contribute to modulation of depression‐like behaviour in C57BL/6J mice”
Published: (2025)

Proteome profile of the cerebellum from α7 nicotinic acetylcholine receptor deficient mice
by: Karolina Magdalena Caban, et al.
Published: (2024)

Comparative analysis of formyl peptide receptor 1 and formyl peptide receptor 2 reveals shared and preserved signalling profiles
by: Denise Pajonczyk, et al.
Published: (2024)

Structural bases for stoichiometry‐selective calcium potentiation of a neuronal nicotinic receptor
by: Simone Mazzaferro, et al.
Published: (2024)

α7 nicotinic acetylcholine receptors induce long‐term synaptic enhancement in the dorsal but not ventral hippocampus
by: Giota Tsotsokou, et al.
Published: (2024)

An α7 nicotinic and GABAB receptor‐mediated pathway controls acetylcholine release in the tripartite neuromuscular junction
by: Konstantin Petrov, et al.
Published: (2024)

Gβγ subunit activation of K V 7 and BK Ca channels underlies calcitonin gene‐related peptide vasorelaxation in myogenic rat coronary resistance arteries
by: Lucy A. Donovan, et al.
Published: (2026)

Histone deacetylase inhibition mitigates cognitive deficits and astrocyte dysfunction induced by amyloid‐β (Aβ) oligomers
by: Luan Pereira Diniz, et al.
Published: (2024)

Differential modulation of BK channels by simvastatin: Critical role of the auxiliary β 4 subunit
by: Gangjing Li, et al.
Published: (2026)

Chemistry/structural biology of psychedelic drugs and their receptor(s)
by: Ryan H. Gumpper, et al.
Published: (2024)

Vagal‐α7 nicotinic acetylcholine receptor signaling exacerbates influenza severity by promoting lung epithelial cell infection
by: Caiqi Zhao, et al.
Published: (2024)

Interleukin‐1 receptor‐associated kinase 4 (IRAK4) is a critical regulator of inflammatory signalling through toll‐like receptors 4 and 7/8 in murine and human lungs
by: Ian Sayers, et al.
Published: (2024)

AdipoRon promotes amyloid‐β clearance through enhancing autophagy via nuclear GAPDH‐induced sirtuin 1 activation in Alzheimer's disease
by: Fengjiao Sun, et al.
Published: (2024)

ST‐2560, a selective inhibitor of the NaV1.7 sodium channel, affects nocifensive and cardiovascular reflexes in non‐human primates
by: John V. Mulcahy, et al.
Published: (2024)

The sodium–glucose co‐transporter 2 inhibitor, empagliflozin, attenuates pulmonary vascular remodelling by inhibiting the phosphorylation of PDGF receptor‐β
by: Ting‐ting Lyu, et al.
Published: (2025)

α-Conotoxin LvID, an antagonist of α7 nicotinic acetylcholine receptor, mitigates Alzheimer-associated phenotypes by inhibiting Aβ deposition and reactive astrogliosis.
by: Yue, Song, et al.
Published: (2026)

InsT‐ALLing CD7 chimeric antigen receptors before transplantation
by: Julio Delgado
Published: (2024)

SGK3 promotes estrogen receptor‐positive breast cancer proliferation by activating STAT3/ZMIZ2 pathway to stabilise β‐catenin
by: Lie Yuan, et al.
Published: (2025)

α‐Linolenic acid suppresses Th17 cell differentiation to mitigate allergic rhinitis by binding to Lyn kinase in mast cells
by: Yuejin Wang, et al.
Published: (2026)

Biphasic effect of nicotine on glutamatergic activity in male mouse brain
by: Prajakta Pramod Biyani, et al.
Published: (2025)

Contribution of chloride channels to the action potential and contraction in human myometrium during labour
by: Helena C. Parkington, et al.
Published: (2025)

Identification of ethanol‐insensitive N‐methyl‐d‐aspartate receptor GluN2A and GluN2B subunit mutants with minimal alterations in ion channel gating
by: Claire M. Fellbaum, et al.
Published: (2025)

Exposure–response relationships of mirvetuximab soravtansine in patients with folate receptor‐α‐positive ovarian cancer: Justification of therapeutic dose regimen
by: Ya‐Ping Tu, et al.
Published: (2024)

Synthesis and evaluation of a novel inhibitor for the α5‐GABA A receptor in the treatment of peripheral neuralgia: Evidence from MD simulation and in vivo studies
by: Yanming Chen, et al.
Published: (2025)

P2X7 receptor antagonism suppresses epileptiform‐like activity in an inflammation‐primed human iPSC‐derived neuron model of drug‐resistant epilepsy
by: Jaideep Kesavan, et al.
Published: (2025)

Ingrilimine, a novel marine cytotoxic and apoptotic cyclic imine toxin with a high affinity and dual activity on human α7 nicotinic acetylcholine receptor.
by: Delepierre, Muriel, et al.
Published: (2026)

Astragaloside II alleviates cardiac hypertrophy by targeting aminoacylase‐1: a novel mechanism via the β ‐catenin/transcription factor 4/ubiquitin C‐terminal hydrolase L1 axis
by: Yangyang Lin, et al.
Published: (2026)

Autocrine activation of P2X7 receptors mediates catecholamine secretion in chromaffin cells
by: María Constanza Maldifassi, et al.
Published: (2024)

State‐dependent regulation of the K v 7.2 channel voltage sensor by QO‐58
by: Richard Kanyo, et al.
Published: (2025)

A novel recombinant peptide, RGD‐Latcripin‐7A, targeting neovascularization in skin transplantation: Tissue regeneration and autophagy mechanism
by: Xuzi Zhang, et al.
Published: (2026)

Postnatal hypofunction of N‐methyl‐D‐aspartate receptors alters perforant path synaptic plasticity and filtering and impairs dentate gyrus‐mediated spatial discrimination
by: Luis A. Márquez, et al.
Published: (2024)

The β 2 ‐adrenoceptor agonist formoterol attenuates hallmarks of adrenal Cushing's syndrome
by: Kristan H. Cleveland, et al.
Published: (2026)

Insight into the regulatory mechanism of β‐arrestin2 and its emerging role in diseases
by: Meng Qi, et al.
Published: (2024)

Effects on cerebral blood flow after single doses of the β2 agonist, clenbuterol, in healthy volunteers and patients with mild cognitive impairment or Parkinson's disease
by: Thomas Lodeweyckx, et al.
Published: (2024)

Efficacy and safety of a selective partial agonist for nociception/orphanin‐FQ peptide (NOP) receptors in patients with insomnia disorder
by: Garth T. Whiteside, et al.
Published: (2025)

A novel peptide‐fentanyl conjugate with μ‐opioid and neuropeptide FF receptor agonism produces antinociception with limited side effects in male mice
by: Ning Li, et al.
Published: (2025)

Variable peptide processing of a Conus (Asprella) neocostatus α-conotoxin generates bioactive toxiforms that are potent against distinct nicotinic acetylcholine receptor subtypes.
by: Ramones, Cydee Marie V, et al.
Published: (2025)

Expression of fibroblast growth factor receptor 1 correlates inversely with the efficacy of single‐agent fibroblast growth factor receptor‐specific inhibitors in pancreatic cancer
by: Qingxiang Lin, et al.
Published: (2024)

Semax peptide targets the μ opioid receptor gene Oprm1 to promote deubiquitination and functional recovery after spinal cord injury in female mice
by: Rongjie Liu, et al.
Published: (2025)

An experimental medicine protocol for exploring the haemodynamic effects of dual agonism at the glucagon‐like peptide‐1 and glucagon receptor in healthy subjects
by: James Goodman, et al.
Published: (2025)