Copertina

Dual effects of mefenamic acid on the IKs molecular complex

Fuente: Wiley Open Access

Salvato in:

Dettagli Bibliografici
Autori principali:	Magnus Chan, Marc Pourrier, Jodene Eldstrom, Harutyun Sahakyan, Vitya Vardanyan, David Fedida
Natura:	Artículo Open Access
Pubblicazione:	Wiley 2024
Soggetti:	British Journal of Pharmacology
Accesso online:	Acceder al recurso
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!

Documenti analoghi

Off‐target effects of statins: molecular mechanisms, side effects and the emerging role of kinases
di: Francisco Alejandro Lagunas‐Rangel, et al.
Pubblicazione: (2024)

Nervonic acid, a long chain monounsaturated fatty acid, improves mitochondrial function in adrenomyeloneuropathy fibroblasts
di: Chenxu Li, et al.
Pubblicazione: (2025)

Chicoric acid exerts therapeutic effects in DSS‐induced ulcerative colitis by targeting the USP9X/IGF2BP2 axis
di: Wei Chen, et al.
Pubblicazione: (2024)

Bleeding in patients on concurrent treatment with a selective serotonin reuptake inhibitor (SSRI) and low‐dose acetylsalicylic acid (ASA) compared with SSRI or low‐dose ASA alone—A systematic review and meta‐analysis
di: Magnus A. B. Axelsson, et al.
Pubblicazione: (2024)

Influence of gut bile acid composition on the glucose‐lowering effect and safety of metformin
di: Deok Yong Yoon, et al.
Pubblicazione: (2024)

Resveratrol, a novel inhibitor of fatty acid binding protein 5, inhibits cervical cancer metastasis by suppressing fatty acid transport into nucleus and downstream pathways
di: Xiao Chen, et al.
Pubblicazione: (2024)

Therapeutic drug monitoring, liquid biopsies or pharmacogenomics for prediction of human drug metabolism and response
di: Magnus Ingelman‐Sundberg, et al.
Pubblicazione: (2024)

Assessment of the molecular mechanisms of drug‐induced hidden cardiotoxicity by a multi‐omics approach: The example of rofecoxib
di: Bennet Y. Weber, et al.
Pubblicazione: (2025)

The role of free‐fatty acid receptors FFA1 and FFA4 in organ fibrosis
di: Priyanka F. Karmokar, et al.
Pubblicazione: (2026)

Short‐chain fatty acids regulate T cell heterogeneity to alleviate recurrent spontaneous abortion
di: Yao Yao, et al.
Pubblicazione: (2025)

In depth: The drug interaction between trimethoprim‐sulfamethoxazole and folic acid/folinic acid
di: Emmy Boerrigter, et al.
Pubblicazione: (2024)

Histone deacetylase‐mediated silencing of PSTPIP2 expression contributes to aristolochic acid nephropathy‐induced PANoptosis
di: Chuanting Xu, et al.
Pubblicazione: (2024)

Fatty acid binding protein 3 activates endothelial adhesion of circulating monocytes and impairs endothelial angiogenesis
di: Yen‐Wen Wu, et al.
Pubblicazione: (2025)

Kynurenic acid as a promising therapeutic agent in renal fibrosis: dual modulation of fibrosis and immune crosstalk
di: Sona Sykorova, et al.
Pubblicazione: (2026)

D‐amino acid oxidase as a chemogenetic tool for spatiotemporally controlled hydrogen peroxide production: The oxygen connection
di: Wiebke Maurer, et al.
Pubblicazione: (2025)

Recent advances in neuroinflammation prevention and therapy: the role of natural products and underlying mechanisms based on molecular targets
di: Mei‐Mei Zhao, et al.
Pubblicazione: (2024)

Chronic stress induces behavioural changes through increased kynurenic acid by downregulation of kynurenine‐3‐monooxygenase with microglial decline
di: Masaya Hasegawa, et al.
Pubblicazione: (2024)

α‐Linolenic acid suppresses Th17 cell differentiation to mitigate allergic rhinitis by binding to Lyn kinase in mast cells
di: Yuejin Wang, et al.
Pubblicazione: (2026)

Fatty acid amide hydrolase (FAAH) and the endocannabinoid system in obesity: Mechanistic insights and pharmacological opportunities beyond incretin‐based therapies
di: Ilaria Serra, et al.
Pubblicazione: (2026)

Enhancing antitumour response to proteasome inhibitors with inhibitors of insulin‐degrading enzyme, a new molecular vulnerability in multiple myeloma
di: Laetitia Lesire, et al.
Pubblicazione: (2026)

The activated caveolin‐3/μ‐opioid receptor complex drives morphine‐induced rescue therapy in failing hearts
di: Chengxiao Guo, et al.
Pubblicazione: (2024)

The anti‐fibrotic effects of novel heart failure pharmacotherapies in advanced heart failure patients
di: Dávid Nagy, et al.
Pubblicazione: (2025)

Hydroxymethylglutaryl‐CoA reductase activity is essential for mitochondrial β‐oxidation of fatty acids to prevent lethal accumulation of long‐chain acylcarnitines in the mouse liver
di: Edgars Liepinsh, et al.
Pubblicazione: (2024)

Why classical receptor theory, which ignores allostery, can effectively measure the strength of an allosteric effect as agonist's efficacy
di: H. Ongun Onaran, et al.
Pubblicazione: (2024)

Inhibition of the calcineurin/forkhead box O1/fatty acid binding protein 4 pathway prevents SERCA2 dysfunction‐induced foam cell formation and atherosclerosis
di: Beibei Zhu, et al.
Pubblicazione: (2025)

Cholinergic G protein‐coupled bile acid receptor 1 (TGR5/GPBA) in the medial septal orchestrates adult hippocampal neurogenesis and cognition in Alzheimer's disease mice
di: Rui‐Zhe Nie, et al.
Pubblicazione: (2025)

Repurposing SGLT2 and DPP‐4 inhibitors for mild cognitive impairment in type 2 diabetes mellitus: Insights from proteomics, target prediction and molecular docking
di: Shams T. Osman, et al.
Pubblicazione: (2026)

Pharmacological and behavioural effects of tryptamines present in psilocybin‐containing mushrooms
di: Ryan J. Rakoczy, et al.
Pubblicazione: (2024)

Anti‐inflammatory and remyelinating effects of fexagratinib in experimental multiple sclerosis
di: Fynn Gurski, et al.
Pubblicazione: (2024)

Biphasic effect of nicotine on glutamatergic activity in male mouse brain
di: Prajakta Pramod Biyani, et al.
Pubblicazione: (2025)

Have plastic culture models prevented the discovery of effective cancer therapeutics?
di: Kevin M. Tharp
Pubblicazione: (2024)

Network medicine and systems pharmacology approaches to predicting adverse drug effects
di: Alessio Funari, et al.
Pubblicazione: (2024)

Circadian time‐dependent effects of experimental colitis on theophylline disposition and toxicity
di: Yi Yang, et al.
Pubblicazione: (2024)

A covalent molecular glue hijacks the E3 ligase MKRN2 to degrade the ribosomal protein RPS7 and induce synthetic lethality in p53‐deficient NSCLC cells
di: Yuqi Pan, et al.
Pubblicazione: (2026)

Pharmacological and molecular characterization of a chalcone analogue derived from a Senecio nutans metabolite: Modulation of Ca V 1.2 and K Ca 1.1 channels in hypertensive rats
di: Daniel Asunción‐Alvarez, et al.
Pubblicazione: (2026)

Artemisinins in autoimmune diseases: effects and mechanisms in systemic lupus erythematosus and rheumatoid arthritis
di: Fanchao Zhou, et al.
Pubblicazione: (2025)

Reconsidering the gamma–delta shift as a biomarker of antidepressant effects of ketamine enantiomers
di: Kenji Hashimoto
Pubblicazione: (2026)

Evaluation of the antihypertensive and antihyperlipidaemic effects of a pyrimidine derivative in preventing cardiometabolic risk
di: Baskar Aswinanand, et al.
Pubblicazione: (2026)

Transcriptional and functional effects of mavacamten in multiple porcine and human models with hypertrophic cardiomyopathy
di: Elisa Kiselev, et al.
Pubblicazione: (2025)

Regulation, effects and monitoring of compartmented cGMP signalling in cardiomyocytes—current status
di: Kjetil Wessel Andressen, et al.
Pubblicazione: (2025)