Buchumschlag

Smooth muscle cell Piezo1 is essential for phenotypic switch and neointimal hyperplasia

Fuente: Wiley Open Access

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	Fei‐Ran Zhang, Jie Tang, Ying Lai, Shi‐Qi Mo, Zhuo‐Miao Lin, Qing‐Qing Lei, Cong‐Cong Han, An‐Dong Zhou, Xiao‐Fei Lv, Cheng Wang, Jing‐Song Ou, Jia‐Guo Zhou, Rui‐Ping Pang
Format:	Artículo Open Access
Veröffentlicht:	Wiley 2025
Schlagworte:	British Journal of Pharmacology
Online-Zugang:	Acceder al recurso
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge

Piezo1‐mediated regulation of smooth muscle cell volume in response to enhanced extracellular matrix rigidity
von: Robert T. Johnson, et al.
Veröffentlicht: (2024)

Involvement of Piezo 1 in inhibition of shear‐induced platelet activation and arterial thrombosis by ginsenoside Rb1
von: Yilin Wang, et al.
Veröffentlicht: (2025)

Dimerisation of the VIP receptor VIPR2 is essential to its binding VIP and Gαi proteins, and to its functions in breast cancer cells
von: Satoshi Asano, et al.
Veröffentlicht: (2025)

Silencing drug transporters in human primary muscle cells modulates atorvastatin pharmacokinetics: A pilot study
von: Emilia Hoste, et al.
Veröffentlicht: (2025)

A long‐acting FGF21 attenuates metabolic dysfunction‐associated steatohepatitis‐related fibrosis by modulating NR4A1‐mediated Ly6C phenotypic switch in macrophages
von: Yue Ji, et al.
Veröffentlicht: (2024)

FM‐dye inhibition of Piezo2 relieves mechanically evoked pain in mouse models of acute inflammatory and osteoarthritic knee pain
von: Natalie S. Adamczyk, et al.
Veröffentlicht: (2026)

Short‐chain fatty acids regulate T cell heterogeneity to alleviate recurrent spontaneous abortion
von: Yao Yao, et al.
Veröffentlicht: (2025)

A comprehensive review of anti‐colorectal cancer alkaloids from traditional Chinese medicine: Sources, chemical structures, mechanisms and therapeutic applications
von: Kaiping Cong, et al.
Veröffentlicht: (2026)

Role of protein kinase A and A kinase anchoring proteins in buffering and compartmentation of cAMP signalling in human airway smooth muscle cells
von: Rinzhin T. Sherpa, et al.
Veröffentlicht: (2024)

Activation of autophagy mediated by PI3K/Akt/mTOR signalling cascade alleviates impaired adipose‐derived stem cell osteogenesis in a diabetic microenvironment
von: Fangzhi Lou, et al.
Veröffentlicht: (2025)

Elucidating the beneficial impact of exercise on chronic obstructive pulmonary disease and its comorbidities: Integrating proteomic and immunological insights
von: Xishuai Wang, et al.
Veröffentlicht: (2024)

The NADPH oxidase inhibitor Vas2870 prevents myocyte ferroptosis and improves cardiac remodelling and function in doxorubicin‐induced cardiomyopathy
von: Jing Wang, et al.
Veröffentlicht: (2026)

Biomimetic MCC950‐loaded cerium‐layered double hydroxide nanoparticles for targeted treatment of Type 1 diabetes in streptozotocin‐induced mice
von: Huiwen Pang, et al.
Veröffentlicht: (2026)

Reply to the Letter to the Editor from Chen Xue entitled “Revisiting the GRK2–NOX4 axis in cisplatin‐induced nephrotoxicity.”
von: Fei Duan, et al.
Veröffentlicht: (2026)

HIF‐1α and adaptor protein LIM and senescent cell antigen‐like domains protein 1 axis promotes tubulointerstitial fibrosis by interacting with vimentin in angiotensin II‐induced hypertension
von: Wei‐Jie Ni, et al.
Veröffentlicht: (2024)

Food‐derived compounds for CYP‐phenotyping
von: Manuel Haschke
Veröffentlicht: (2024)

Factor XII and prekallikrein promote microvascular inflammation and psoriasis in mice
von: Yurong Zhang, et al.
Veröffentlicht: (2024)

Development of a novel tyrosine kinase 2 inhibitor ARTS‐011 and its first‐in‐human single and multiple ascending dose Phase I study to evaluate the tolerability, safety, pharmacokinetic profile and food effects
von: Zhili Jin, et al.
Veröffentlicht: (2026)

Nimodipine reduces microglial activation in vitro as evidenced by morphological phenotype, phagocytic activity and high‐throughput RNA sequencing
von: István Pesti, et al.
Veröffentlicht: (2025)

SEW2871 attenuates myocyte necroptosis in heart failure through inhibition of oxidative stress and inflammatory cytokines
von: Hong‐Xia Guo, et al.
Veröffentlicht: (2025)

Beyond TGFβ inhibition: Chitosan oligosaccharide targets PGC‐1α‐mediated mitochondrial repair to combat pulmonary fibrosis
von: Huan He, et al.
Veröffentlicht: (2025)

The safety profile of usage of glucagon‐like peptide‐1 receptor agonists in pregnancy: A pharmacovigilance analysis based on the Food and Drug Administration Adverse Event Reporting System
von: Jianxing Zhou, et al.
Veröffentlicht: (2024)

GNS561 (ezurpimtrostat), a small basic lipophilic molecule, prevents lupus phenotype in a pristane‐induced lupus mouse model
von: Eya Toumi, et al.
Veröffentlicht: (2025)

Hydroxymethylglutaryl‐CoA reductase activity is essential for mitochondrial β‐oxidation of fatty acids to prevent lethal accumulation of long‐chain acylcarnitines in the mouse liver
von: Edgars Liepinsh, et al.
Veröffentlicht: (2024)

Antidiabetic DPP4 inhibitor Attenuates Intervertebral Disc Degeneration via Macrophage‐Nucleus Pulposus Cell Crosstalk
von: Chen‐Cheng Zhou, et al.
Veröffentlicht: (2026)

TREM2 activation reduces white matter injury via PI3K/Akt/GSK‐3β signalling after intracerebral haemorrhage
von: Yuan Zhang, et al.
Veröffentlicht: (2025)

Sevoflurane acts as an antidepressant by suppression of GluN2D‐containing NMDA receptors on interneurons
von: Fei Guo, et al.
Veröffentlicht: (2024)

Asthma and inflammation transcriptionally up‐regulate the aryl hydrocarbon receptor in airway smooth muscle via p38/JNK‐AP1 signalling
von: Mohammad Irshad Reza, et al.
Veröffentlicht: (2025)

EXPRESSION OF CONCERN: Superoxide from NADPH Oxidase Upregulates Type 5 Phosphodiesterase in Human Vascular Smooth Muscle Cells: Inhibition with Iloprost and NONOate
Veröffentlicht: (2025)

Effective remimazolam induction dose in paediatric same‐day bidirectional endoscopy: A biased coin up and down sequential trial
von: Si‐Qi Zhou, et al.
Veröffentlicht: (2025)

The impact of Foxp3 + regulatory T‐cells on CD8 + T‐cell dysfunction in tumour microenvironments and responses to immune checkpoint inhibitors
von: Mikhaël Attias, et al.
Veröffentlicht: (2024)

Solanidine‐derived CYP2D6 phenotyping elucidates phenoconversion in multimedicated geriatric patients
von: Jens Andreas Sarömba, et al.
Veröffentlicht: (2025)

α‐Linolenic acid suppresses Th17 cell differentiation to mitigate allergic rhinitis by binding to Lyn kinase in mast cells
von: Yuejin Wang, et al.
Veröffentlicht: (2026)

A single‐centre analysis of a biosimilar switching programme for adalimumab in inflammatory bowel disease
von: Louise Rabbitt, et al.
Veröffentlicht: (2025)

Effects of vaccines targeting interleukin‐1 receptor, type I on atrial and ventricular function after myocardial infarction
von: Jianwu Huang, et al.
Veröffentlicht: (2026)

A novel synthesised STAT3 inhibitor exerts potent anti‐tumour activity by inducing lysosome‐dependent cell death
von: Marvin Xuejun Xu, et al.
Veröffentlicht: (2025)

Exploring drug mechanisms through single‐cell proteomics
von: Yuzhi Sun, et al.
Veröffentlicht: (2026)

Blockade of CaV3 calcium channels and induction of G0/G1 cell cycle arrest in colon cancer cells by gossypol
von: Osbaldo Lopez‐Charcas, et al.
Veröffentlicht: (2024)

Interindividual variability in olanzapine steady‐state concentrations in Chinese: exploring single nucleotide polymorphisms of metabolic enzymes
von: Zhou Wan, et al.
Veröffentlicht: (2025)

Safety and pharmacokinetics of a novel potent GABA analogue crisugabalin in Chinese subjects with various degrees of renal impairment
von: Shibeilei Lin, et al.
Veröffentlicht: (2025)