Buchumschlag

EpigenPlot: An interactive web platform for DNA methylation‐based biomarker and drug target discovery in colorectal cancer

Fuente: Wiley Open Access

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	Dalma Müller, Balázs Győrffy
Format:	Artículo Open Access
Veröffentlicht:	Wiley 2025
Schlagworte:	British Journal of Pharmacology
Online-Zugang:	Acceder al recurso
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge

TNMplot: An enhanced platform for pharmacological target identification through cross‐stage and pan‐cancer gene expression analysis
von: Áron Bartha, et al.
Veröffentlicht: (2026)

Pathway‐level mutational signatures predict breast cancer outcomes and reveal therapeutic targets
von: Máté Posta, et al.
Veröffentlicht: (2025)

Novel approaches for the discovery of pharmacogenetic biomarkers of chemotoxicity in patients with colorectal cancer
von: Ana Rita Simoes, et al.
Veröffentlicht: (2025)

Artificial intelligence streamlines scientific discovery of drug–target interactions
von: Yuxin Yang, et al.
Veröffentlicht: (2025)

Non‐canonical nitric oxide signalling and DNA methylation: Inflammation induced epigenetic alterations and potential drug targets
von: Christopher H. Switzer
Veröffentlicht: (2024)

Natural products and cancer: From drug discovery to prevention and therapy
von: Angelo A. Izzo, et al.
Veröffentlicht: (2025)

The eyes of the beholder: Perceived barriers to successful drug repurposing
von: Zsuzsanna Ida Petykó, et al.
Veröffentlicht: (2025)

Unravelling the multifaceted actions of neurosteroids: Machine learning and in vitro screening for novel target discovery
von: Ajeet Kumar, et al.
Veröffentlicht: (2025)

The use of different types of networks, alone and in combination, for drug target identification
von: Paolo Parini
Veröffentlicht: (2025)

Have plastic culture models prevented the discovery of effective cancer therapeutics?
von: Kevin M. Tharp
Veröffentlicht: (2024)

A computer‐aided drug repurposing: the antibacterial agents targeting GroEL
von: Dongdong Zhang, et al.
Veröffentlicht: (2025)

Structure‐based discovery of thiamine uptake inhibitors
von: Florian Gabriel, et al.
Veröffentlicht: (2025)

Cost‐effectiveness of DPYD genotyping prior to fluoropyrimidine‐based treatment for colorectal cancer in Wales
von: Catrin O. Plumpton, et al.
Veröffentlicht: (2026)

Systematic drug screening and target analysis identify digitoxin as a potential therapy for uveal melanoma
von: Huilin Liu, et al.
Veröffentlicht: (2024)

Protein tyrosine phosphatases as emerging targets for cancer immunotherapy
von: Zihan Qu, et al.
Veröffentlicht: (2024)

Altered desensitization and internalization patterns of rodent versus human glucose‐dependent insulinotropic polypeptide (GIP) receptors. An important drug discovery challenge
von: Lærke Smidt Gasbjerg, et al.
Veröffentlicht: (2024)

MicroRNA‐guided drug discovery for mitigating persistent pulmonary complications in critical COVID‐19 survivors: A longitudinal pilot study
von: María C. García‐Hidalgo, et al.
Veröffentlicht: (2024)

Pharmacology and relevant drug interactions of metamizole
von: David J. Brinkman, et al.
Veröffentlicht: (2025)

Potential of natural flavonoids to target breast cancer angiogenesis (review)
von: Yuetong Wang, et al.
Veröffentlicht: (2024)

System level network data and models attack cancer drug resistance
von: Márk Kerestély, et al.
Veröffentlicht: (2025)

Experience of a nirmatrelvir/ritonavir drug–drug interaction expert advice service
Veröffentlicht: (2024)

Breaking the barriers: Overcoming cancer resistance by targeting the NLRP3 inflammasome
von: Nazanin Pazhouhesh Far, et al.
Veröffentlicht: (2024)

Targeted peptide‐modified M2 exosomes drug delivery system for the targeted regulation of the lung injury microenvironment with isorhynchophylline (IRN): based on the inflammatory–metabolic–epigenetic synergy mechanism
von: Jin‐Ru Zou, et al.
Veröffentlicht: (2026)

Predicting drug–drug interactions between ainuovirine and rifampicin plus isoniazid using PBPK modelling
Veröffentlicht: (2024)

Synergistic RU486 and olaparib therapy enhances apoptosis in endometriosis by simultaneously targeting hormonal signalling and DNA repair
von: Yujie Peng, et al.
Veröffentlicht: (2026)

A comprehensive review of anti‐colorectal cancer alkaloids from traditional Chinese medicine: Sources, chemical structures, mechanisms and therapeutic applications
von: Kaiping Cong, et al.
Veröffentlicht: (2026)

A case report highlighting drug–drug interactions between 3 life‐saving treatments: Feminizing hormones, antiretrovirals and antituberculosis drugs
von: Tara Suchak, et al.
Veröffentlicht: (2024)

Exploring the link between antihypertensive drugs targets and pancreatitis risk through Mendelian randomization
von: Zhiwei Du, et al.
Veröffentlicht: (2025)

Identification of prokineticin‐2 as potential pharmacodynamic biomarker for overcoming doxorubicin resistance in multicellular breast cancer spheroids
von: Martina Vincenzi, et al.
Veröffentlicht: (2025)

A drug–drug interaction study and physiologically based pharmacokinetic modelling to assess the effect of an oral 5‐lipoxygenase activating protein inhibitor on the pharmacokinetics of oral midazolam
von: Jane Knöchel, et al.
Veröffentlicht: (2024)

Pharmacokinetic drug–drug interactions with flucloxacillin and other isoxazolyl penicillins: A systematic literature review and practical guide
von: Julia M. Wortman, et al.
Veröffentlicht: (2026)

Clinical pharmacology considerations and drug–drug interactions with long‐acting cabotegravir and rilpivirine relevant to sub‐Saharan Africa
von: Adrian Steulet, et al.
Veröffentlicht: (2024)

Establishing reference ranges for circulating biomarkers of drug‐induced liver injury in healthy human volunteers 1
von: Andrea L. Jorgensen, et al.
Veröffentlicht: (2024)

Evaluating the capability of ChatGPT in predicting drug–drug interactions: Real‐world evidence using hospitalized patient data
von: Ramya Padmavathy Radha Krishnan, et al.
Veröffentlicht: (2024)

Single‐dose and steady‐state pharmacokinetics of clomipramine, yohimbine and clomipramine/yohimbine combination: A clinical drug–drug interaction study
von: Amelie Leutzendorff, et al.
Veröffentlicht: (2024)

In depth: The drug interaction between trimethoprim‐sulfamethoxazole and folic acid/folinic acid
von: Emmy Boerrigter, et al.
Veröffentlicht: (2024)

A mitochondria‐targeting and G‐quadruplex structure‐binding ligand inducing calcium overload and ferroptosis in human cancer cells
von: Bo‐Xin Zheng, et al.
Veröffentlicht: (2025)

Advancing antihypertensive drug development
von: Fay Pu, et al.
Veröffentlicht: (2025)

Drug–drug interaction profile of ritlecitinib as perpetrator and victim through cytochrome P450
von: Vivek S. Purohit, et al.
Veröffentlicht: (2025)

Quantitative prediction of intravenous drug interactions caused by cytochromes P450 inhibitors and inducers
von: Vianney Tuloup, et al.
Veröffentlicht: (2026)