Copertina

Vestibular modulation by stimulant derivatives in a pentameric ligand‐gated ion channel

Fuente: Wiley Open Access

Salvato in:

Dettagli Bibliografici
Autori principali:	Emelia Karlsson, Olivia Andén, Chen Fan, Zaineb Fourati, Ahmed Haouz, Yuxuan Zhuang, Rebecca J. Howard, Marc Delarue, Erik Lindahl
Natura:	Artículo Open Access
Pubblicazione:	Wiley 2025
Soggetti:	British Journal of Pharmacology
Accesso online:	Acceder al recurso
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!

Documenti analoghi

Photochemical control of cold‐sensitive TRPA1 ion channel gating for modulation of pain sensation
di: Junli Peng, et al.
Pubblicazione: (2025)

Biodiversity2Drugs—Renaissance of exploring nature‐derived peptides for GPCR ligand discovery
di: Christian W. Gruber, et al.
Pubblicazione: (2025)

Identification of ethanol‐insensitive N‐methyl‐d‐aspartate receptor GluN2A and GluN2B subunit mutants with minimal alterations in ion channel gating
di: Claire M. Fellbaum, et al.
Pubblicazione: (2025)

Progress on the development of Class A GPCR‐biased ligands
di: Paula Morales, et al.
Pubblicazione: (2024)

Flecainide binding dynamics in voltage‐gated sodium channels: A comparative isoform analysis of the state‐dependent block
di: Tatsuo Munakata, et al.
Pubblicazione: (2026)

Hydroxyl chalcone derivative DK02 as a multi‐target‐directed ligand for Alzheimer's disease: A preclinical study in zebrafish
di: Balasubramanian Haridevamuthu, et al.
Pubblicazione: (2024)

The ion channel TRPM8 is a direct target of the immunosuppressant rapamycin in primary sensory neurons
di: José Miguel Arcas, et al.
Pubblicazione: (2024)

Anti‐nociceptive action of leonurine through TRPA1 and TRPV4 channels modulation
di: Matilde Marini, et al.
Pubblicazione: (2025)

Differential modulation of BK channels by simvastatin: Critical role of the auxiliary β 4 subunit
di: Gangjing Li, et al.
Pubblicazione: (2026)

A comment on the interpretation of ligand binding experiments for agonists
di: James P. Higham
Pubblicazione: (2025)

Neuronal and ion channel mechanisms of noxious heat sensing in mammals: A puzzle of sensory physiology and pharmacology
di: Gábor Pethő, et al.
Pubblicazione: (2026)

Endothelium‐ and epithelium‐derived novel endogenous catecholamines as modulators of the autonomic nervous system
di: Mariana G. de Oliveira, et al.
Pubblicazione: (2026)

Pharmacological profiling of small molecule modulators of the TMEM16A channel and their implications for the control of artery and capillary function
di: Rumaitha Al‐Hosni, et al.
Pubblicazione: (2025)

Bioactive ligands targeting ectopic olfactory receptors: Implications for therapeutic strategies
di: Hui Zhao, et al.
Pubblicazione: (2025)

Comprehensive transduceromic profiling of NOP receptor ligands at different Gα subunits
di: Davide Malfacini, et al.
Pubblicazione: (2026)

Transient receptor potential ankyrin 1 channel modulates the abuse‐related mechanisms of methamphetamine through interaction with dopamine transporter
di: Kwang‐Hyun Hur, et al.
Pubblicazione: (2024)

Activation of peripheral cannabinoid receptors by CB13 attenuates burn injury–induced chronic pain through TRP channel modulation
di: Obulapathi Ummadisetty, et al.
Pubblicazione: (2026)

The contribution of NaV1.6 to the efficacy of voltage‐gated sodium channel inhibitors in wild type and NaV1.6 gain‐of‐function (GOF) mouse seizure control
di: James P. Johnson, et al.
Pubblicazione: (2024)

Clinically relevant niclosamide concentrations modulate TMEM16A and CaV1.2 channels to control artery tone and capillary diameter
di: Rachel Kaye, et al.
Pubblicazione: (2025)

Variable electrophysiology before and after block of the two delayed rectifier potassium channels in groups of isolated rabbit ventricular cells
di: Rebecca J. Gilchrist, et al.
Pubblicazione: (2026)

A mitochondria‐targeting and G‐quadruplex structure‐binding ligand inducing calcium overload and ferroptosis in human cancer cells
di: Bo‐Xin Zheng, et al.
Pubblicazione: (2025)

Pharmacology of PIEZO1 channels
di: Jacob A. Kinsella, et al.
Pubblicazione: (2024)

TRPV4 stimulates colonic afferents through mucosal release of ATP and glutamate
di: Michelle Y. Meng, et al.
Pubblicazione: (2024)

Elucidation of the zinc binding site in KCNQ channels
di: Shuo Zhang, et al.
Pubblicazione: (2025)

Pharmacological and molecular characterization of a chalcone analogue derived from a Senecio nutans metabolite: Modulation of Ca V 1.2 and K Ca 1.1 channels in hypertensive rats
di: Daniel Asunción‐Alvarez, et al.
Pubblicazione: (2026)

Early erythroferrone levels can predict the long‐term haemoglobin responses to erythropoiesis‐stimulating agents
di: Peng Xu, et al.
Pubblicazione: (2024)

The Concise Guide to PHARMACOLOGY 2025/26: Ion channels
di: Stephen P. H. Alexander, et al.
Pubblicazione: (2025)

Opening closed inward rectifier potassium channel doors
di: Anna Stary‐Weinzinger, et al.
Pubblicazione: (2026)

Inactivation induced by pathogenic Cav1.3 L‐type Ca2+‐channel variants enhances sensitivity for dihydropyridine Ca2+ channel blockers
di: Ferenc Török, et al.
Pubblicazione: (2024)

Novel FKBP prolyl isomerase 1A (FKBP12) ligand promotes functional improvement in SOD1G93A amyotrophic lateral sclerosis (ALS) mice
di: Laura Moreno‐Martinez, et al.
Pubblicazione: (2025)

Pharmacodynamics of the orexin type 1 (OX1) receptor in colon cancer cell models: A two‐sided nature of antagonistic ligands resulting from partial dissociation of Gq
di: Valérie Gratio, et al.
Pubblicazione: (2024)

EXPRESSION OF CONCERN: Rosiglitazone and 15‐deoxy‐Δ 12,14 ‐prostaglandin J 2 , ligands of the peroxisome proliferator‐activated receptor‐γ (PPAR‐γ), reduce ischaemia/reperfusion injury of the gut
Pubblicazione: (2024)

Development of new Kir2.1 channel openers from propafenone analogues
di: Encan Li, et al.
Pubblicazione: (2024)

Arbidol, an antiviral drug, identified as a sodium channel blocker with anticonvulsant activity
di: Min Li, et al.
Pubblicazione: (2024)

Contribution of chloride channels to the action potential and contraction in human myometrium during labour
di: Helena C. Parkington, et al.
Pubblicazione: (2025)

Ethosuximide: Subunit‐ and Gβγ‐dependent blocker and reporter of allosteric changes in GIRK channels
di: Boris Shalomov, et al.
Pubblicazione: (2025)

TREM2 activation suppresses central sensitisation by promoting autophagy in a chronic migraine model with recurrent nitroglycerin stimulation in mice
di: Suifa Hu, et al.
Pubblicazione: (2026)

The TREK‐1 potassium channel is a potential pharmacological target for vasorelaxation in pulmonary hypertension
di: Réka Csáki, et al.
Pubblicazione: (2024)

An orally available Cav2.2 calcium channel inhibitor for the treatment of neuropathic pain
di: Janine Kutzsche, et al.
Pubblicazione: (2024)

Opportunities of patient‐derived organoids in drug development
di: Antonia Büning, et al.
Pubblicazione: (2025)