The medicinal chemistry of piperazines: A review
Fuente:
Wiley Open Access
Saved in:
| Main Authors: | Md Faizan, Rajnish Kumar, Avijit Mazumder, Salahuddin, Neelima Kukreti, Arvind Kumar, M. V. N. L. Chaitanya |
|---|---|
| Format: | Artículo Open Access |
| Published: |
Wiley
2024
|
| Subjects: | |
| Online Access: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
Substrate‐based synthetic strategies and biological activities of 1,3,4‐oxadiazole: A review
by: Upasana Sharma, et al.
Published: (2024)
by: Upasana Sharma, et al.
Published: (2024)
Fused and Substituted Piperazines as Anticancer Agents: A Review
by: Saumya Singh, et al.
Published: (2025)
by: Saumya Singh, et al.
Published: (2025)
Design, synthesis, in silico molecular docking, and ADMET studies of quinoxaline‐isoxazole‐piperazine conjugates as EGFR‐targeting agents
by: Mohammad Imtiyaz Ali, et al.
Published: (2024)
by: Mohammad Imtiyaz Ali, et al.
Published: (2024)
Role of PD‐1 in Skin Cancer: Molecular Mechanism, Clinical Applications, and Resistance
by: Neha Sharma, et al.
Published: (2024)
by: Neha Sharma, et al.
Published: (2024)
Design, Synthesis, Molecular Docking, ADME ‐T and In Vitro Anticancer Assessment of Phenyl‐Substituted‐Pyrimidin‐Benzenesulfonamide Derivatives as Potential BRAF V600E / WT Inhibitors
by: Ankit Kumar Singh, et al.
Published: (2025)
by: Ankit Kumar Singh, et al.
Published: (2025)
A recent update on huprine and its hybrids as a potential multifunctional agent for the treatment of Alzheimer's disease
by: Yash Pal Singh, et al.
Published: (2024)
by: Yash Pal Singh, et al.
Published: (2024)
A Comprehensive Analysis on Galantamine Based Hybrids for the Management of Alzheimer's Disease
by: Yash Pal Singh, et al.
Published: (2024)
by: Yash Pal Singh, et al.
Published: (2024)
Exploring the Artificial Intelligence and Its Impact in Pharmaceutical Sciences: Insights Toward the Horizons Where Technology Meets Tradition
by: Shruti Bharadwaj, et al.
Published: (2024)
by: Shruti Bharadwaj, et al.
Published: (2024)
Design and Development of Novel Hybrids Based on Pyrrolo[2,1‐f][1,2,4]Triazine and 1‐(Methylpiperidin‐4‐yl) Aniline–Based Analogs: Exploring the Utility as Anticancer Agents via MERTK Inhibition
by: Balaji Dashrath Sathe, et al.
Published: (2024)
by: Balaji Dashrath Sathe, et al.
Published: (2024)
Dietary Natural Flavonoids: Intervention for MAO‐B Against Parkinson's Disease
by: Ashini Singh, et al.
Published: (2024)
by: Ashini Singh, et al.
Published: (2024)
Novel carbamodithioate regulates cellular hypoxia through chemical activation of prolyl hydroxylase‐2 for breast cancer chemoprevention
by: Shubham Rastogi, et al.
Published: (2024)
by: Shubham Rastogi, et al.
Published: (2024)
Exploring anticancer properties of the phytoconstituents and comparative analysis of their chemical space parameters with USFDA‐approved synthetic anticancer agents
by: Somesh Thapliyal, et al.
Published: (2024)
by: Somesh Thapliyal, et al.
Published: (2024)
Melatonin and its bioisosteres as potential therapeutic agents for the treatment of retinopathy of prematurity
by: N. A. Osipova, et al.
Published: (2024)
by: N. A. Osipova, et al.
Published: (2024)
Multifaceted In Silico Screening Strategies Identifies Potent Inhibitors Facilitating Inhibition of ZNF726 Activity in Breast Cancer
by: Shreetama Bandyopadhayaya, et al.
Published: (2025)
by: Shreetama Bandyopadhayaya, et al.
Published: (2025)
Transition metal complexes of hydrazones as potential antimicrobial and anticancer agents: A short review
by: Izabela Czyżewska, et al.
Published: (2024)
by: Izabela Czyżewska, et al.
Published: (2024)
Click chemistry beyond metal‐catalyzed cycloaddition as a remarkable tool for green chemical synthesis of antifungal medications
by: Azar Tahghighi, et al.
Published: (2024)
by: Azar Tahghighi, et al.
Published: (2024)
Design, synthesis, and biological evaluation of novel quinoxaline aryl ethers as anticancer agents
by: Srinuvasu Nakka, et al.
Published: (2024)
by: Srinuvasu Nakka, et al.
Published: (2024)
Design, Synthesis, and Evaluation of Bis ‐Chalcones and Bis ‐Flavones as Selective COX ‐2 Inhibitors
by: Rui Pereira, et al.
Published: (2026)
by: Rui Pereira, et al.
Published: (2026)
Computational Based Identified EAAT2 Transporter Activator Attenuates Amyloid‐β Induced Excitotoxicity in Primary Neuronal‐Astroglial Mixed Culture by Ameliorating Glutamate Clearance
by: Chennu Manisha, et al.
Published: (2026)
by: Chennu Manisha, et al.
Published: (2026)
Multi‐Omics and Machine Learning‐Driven Discovery of ABCC8 ( SUR1 ) for Diabetes Mellitus: Integrating Molecular Insights on Nigella sativa Bioactives and Sulfonylurea
by: Mohd Adnan, et al.
Published: (2026)
by: Mohd Adnan, et al.
Published: (2026)
Assessment of Antidiarrheal Activity of Fraxin in Chick: Synergistic Effects and Molecular Docking Study
by: Wahidul Alam, et al.
Published: (2026)
by: Wahidul Alam, et al.
Published: (2026)
Integrated Virtual Screening and Molecular Dynamics Simulation Study to Discover Potential Activators of γ‐Aminobutyric Acid B Receptor 1 for Therapeutic Targeting of Neurodegenerative Diseases
by: Asfiya, et al.
Published: (2026)
by: Asfiya, et al.
Published: (2026)
Isoxazole and Pyrazole Derivatives of 28‐Oxo‐Allobetulone Target Viral Membrane Glycoprotein Hemagglutinin
by: Irina E. Smirnova, et al.
Published: (2025)
by: Irina E. Smirnova, et al.
Published: (2025)
In silico optimization of analogs derived pro‐adrenomedullin peptide to evaluate antimicrobial potential
by: Raquel M. Quigua‐Orozco, et al.
Published: (2024)
by: Raquel M. Quigua‐Orozco, et al.
Published: (2024)
Diethoxyphosphoryloxy‐oleanolic acid is a nanomolar‐inhibitor of butyrylcholinesterase
by: Anastasiya V. Petrova, et al.
Published: (2024)
by: Anastasiya V. Petrova, et al.
Published: (2024)
Herbacetin Inhibits Human Fructose 1,6‐Bisphosphatase Among a Panel of Chromone Derivatives and Pyrazoles, Demonstrating Positive Effects on Insulin‐Resistant HepG2 Cells
by: Sónia Rocha, et al.
Published: (2024)
by: Sónia Rocha, et al.
Published: (2024)
Computationally Guided Structural Modification of Centaureidin: A Novel Approach for Enhancing Antioxidant and Antitumor Activities for Drug Development
by: Reem S. Alruhaimi, et al.
Published: (2025)
by: Reem S. Alruhaimi, et al.
Published: (2025)
Spacered With Tetrazole Oleanolic and Ursolic Indolo‐Acids Are Strong Inhibitors of α‐Glucosidase
by: Anastasiya V. Petrova, et al.
Published: (2025)
by: Anastasiya V. Petrova, et al.
Published: (2025)
Synthesis and Molecular Modeling Studies of New Thiadiazole‐Thiophene Compounds as Potent Antimicrobial Agents
by: Nuha M. Halawani, et al.
Published: (2025)
by: Nuha M. Halawani, et al.
Published: (2025)
Discovery of 1‐(Cyclopropylmethyl)‐2‐(Dibenzo[b,d]Thiophen‐2‐yl)‐1H‐Benzo[d]Imidazole‐5‐Carboxylic Acid as Orally Bioavailable EP4 Receptor Antagonist
by: Sanjay Kumar, et al.
Published: (2025)
by: Sanjay Kumar, et al.
Published: (2025)
Targeting Cancer Cell Proliferation Using Piperazine‐Linked Quinolinequinones: Mechanism and Metabolic Profile
by: Ayse Mine Yilmaz, et al.
Published: (2025)
by: Ayse Mine Yilmaz, et al.
Published: (2025)
N‐Substituted‐5‐ [(2,5‐Dihydroxybenzyl)amino]salicylamides as Lavendustin Analogs: Antiproliferative Activity, COMPARE Analyses, Mechanistic, Docking, ADMET and Toxicity Studies
by: Hajjaj H. M. Abdu‐Allah, et al.
Published: (2025)
by: Hajjaj H. M. Abdu‐Allah, et al.
Published: (2025)
Pyrazoline–Imidazopyridine Hybrids as Beclin‐1 Mimetics Driving Dual Apoptotic and Autophagy in Breast Cancer
by: Rashmi Shivakumar, et al.
Published: (2026)
by: Rashmi Shivakumar, et al.
Published: (2026)
99mTc‐HYNIC PEGylated Peptide Probe Targeting HER2‐Expression in Breast Cancer
by: Sushree Arpitabala Yadav, et al.
Published: (2025)
by: Sushree Arpitabala Yadav, et al.
Published: (2025)
Discovery of Novel Oxadiazole‐Triazole Hybrids as Lung and Cervical Cancer Agents: Synthesis, Docking, Biological Evaluation, and SAR Studies
by: Venkatraman Hegde, et al.
Published: (2025)
by: Venkatraman Hegde, et al.
Published: (2025)
From Virtual Screening to Cell Phenotype: 4‐Thiazolidone Scaffolds Targeting LOXL2 in Breast Cancer
by: Sandra Ferreira, et al.
Published: (2026)
by: Sandra Ferreira, et al.
Published: (2026)
Synthesis of New Thiazole‐Pyrazole Analogues: Molecular Modelling, Antiproliferative/Antiviral Activities, and ADME Studies
by: Hind A. Siddiq, et al.
Published: (2025)
by: Hind A. Siddiq, et al.
Published: (2025)
Design, Synthesis and Pro‐Inflammatory Activity of Palmitoylated Derivatives of Thioglycolic Acid as New Immunomodulators
by: Samia M. Mohamed, et al.
Published: (2024)
by: Samia M. Mohamed, et al.
Published: (2024)
Exploring Thiazole‐Based Heterocycles: Synthesis, Bioactivity, and Molecular Docking for Antimicrobial Applications
by: Hana M. Abumelha, et al.
Published: (2025)
by: Hana M. Abumelha, et al.
Published: (2025)
Directed Design, Screening and Antiglycation Activity for 3‐Substituted Thiazolium Derivatives, New Analogs of Alagebrium
by: Olga N. Zhukovskaya, et al.
Published: (2024)
by: Olga N. Zhukovskaya, et al.
Published: (2024)
Similar Items
-
Substrate‐based synthetic strategies and biological activities of 1,3,4‐oxadiazole: A review
by: Upasana Sharma, et al.
Published: (2024) -
Fused and Substituted Piperazines as Anticancer Agents: A Review
by: Saumya Singh, et al.
Published: (2025) -
Design, synthesis, in silico molecular docking, and ADMET studies of quinoxaline‐isoxazole‐piperazine conjugates as EGFR‐targeting agents
by: Mohammad Imtiyaz Ali, et al.
Published: (2024) -
Role of PD‐1 in Skin Cancer: Molecular Mechanism, Clinical Applications, and Resistance
by: Neha Sharma, et al.
Published: (2024) -
Design, Synthesis, Molecular Docking, ADME ‐T and In Vitro Anticancer Assessment of Phenyl‐Substituted‐Pyrimidin‐Benzenesulfonamide Derivatives as Potential BRAF V600E / WT Inhibitors
by: Ankit Kumar Singh, et al.
Published: (2025)