Cover Image

A hybrid evaluation of the intestinal absorption performance of compounds from molecular structure

Fuente: Wiley Open Access

Saved in:

Bibliographic Details
Main Authors:	Mengke Sheng, Lina Ma, Zhixun Li, Xinhui Peng, Shuai Cen, Minfang Feng, Yuting Tian, Xingxing Dai, Xinyuan Shi
Format:	Artículo Open Access
Published:	Wiley 2024
Subjects:	Chemical Biology & Drug Design
Online Access:	Acceder al recurso
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Synthesis and cytotoxic evaluation of heterocyclic compounds by vinylic substitution of ketene dithioacetals
by: Larissa R. S. P. Baliza, et al.
Published: (2024)

Synthesis and evaluation of di‐heterocyclic benzazole compounds as potential antibacterial and anti‐biofilm agents against Staphylococcus aureus
by: Mine Buga Aktekin, et al.
Published: (2024)

Mechanistic insights into targeting caspase‐3 activation and alveolar macrophage pyroptosis by Ephedra and bitter almond compounds for treating pediatric pneumonia via network pharmacology and bioinformatics
by: Lei Wang, et al.
Published: (2024)

Novel phenylpiperazine derivatives as potent transient receptor potential vanilloid 1 antagonists
by: Lina Jing, et al.
Published: (2024)

A recent update on huprine and its hybrids as a potential multifunctional agent for the treatment of Alzheimer's disease
by: Yash Pal Singh, et al.
Published: (2024)

Correction to Analysis of bioactive compounds using LC – ESI – MS / MS , cytotoxic, antimicrobial effects, and enzyme activities from Cyclotrichium origanifolium
Published: (2024)

Prediction of Drug‐Induced Liver Injury: From Molecular Physicochemical Properties and Scaffold Architectures to Machine Learning Approaches
by: Yulong Zhao, et al.
Published: (2024)

Systematic profiling of Taxol resistance and sensitivity to tubulin missence mutations at molecular and cellular levels
by: Lihua Zhou, et al.
Published: (2024)

Role of Qufeng Tongqiao Prescription in the protection of cerebral ischemia and associated molecular network mechanism
by: Xue Bai, et al.
Published: (2024)

In silico optimization of analogs derived pro‐adrenomedullin peptide to evaluate antimicrobial potential
by: Raquel M. Quigua‐Orozco, et al.
Published: (2024)

Design, synthesis, and biological evaluation of novel quinoxaline aryl ethers as anticancer agents
by: Srinuvasu Nakka, et al.
Published: (2024)

Glutamine Attenuates Inflammation and Oxidative Stress in Ulcerative Colitis by Suppressing Wilms' Tumor 1 Associated Protein‐Mediated N6‐Methyladenosine Modification of Nuclear Receptor Coactivator 3
by: Liangxian Jiang, et al.
Published: (2025)

Design, synthesis, in silico molecular docking, and ADMET studies of quinoxaline‐isoxazole‐piperazine conjugates as EGFR‐targeting agents
by: Mohammad Imtiyaz Ali, et al.
Published: (2024)

Network pharmacology analysis and experimental evaluations of YH complex on androgenetic alopecia by regulating the androgenic‐apoptotic axis
by: Mi Hye Kim, et al.
Published: (2024)

Structural and molecular insights from dual inhibitors of EGFR and VEGFR2 as a strategy to improve the efficacy of cancer therapy
by: Krisyanti Budipramana, et al.
Published: (2024)

Design, synthesis and neuroprotective biological evaluation of novel HDAC6 inhibitors incorporating benzothiadiazinyl systems as cap groups
by: Bo Han, et al.
Published: (2024)

Design, synthesis, and evaluation of novel bistrifluoromethyl‐based hydrazones as dual inhibitors of acetylcholinesterase and carbonic anhydrase enzymes for Alzheimer's disease
by: Efe Doğukan Dincel, et al.
Published: (2024)

Discovery of novel chromone and acrylate‐based pancreatic lipase inhibitors: Molecular modelling, synthesis, and in vitro evaluation for the treatment of obesity
by: Prashant S. Auti, et al.
Published: (2024)

An integrated network pharmacology and molecular docking approach to reveal the role of Arctigenin against Cutibacterium acnes‐induced skin inflammation by targeting the CYP19A1
by: Xiaoyan Lu, et al.
Published: (2024)

Multimodal Fusion of mpMRI Radiomics, Clinical Features, and Hematological Biomarkers Enhances Machine Learning‐Based Prediction of Biochemical Recurrence in Prostate Cancer Patients
by: Yinxing Zhu, et al.
Published: (2025)

Prunetin Protects Against Sepsis‐Induced Acute Lung Injury by Inhibiting Inflammation and Oxidative Stress via Regulating the TLR4 / NF ‐ κB / NLRP 3 Inflammasome Pathway
by: Xuedong Zhang, et al.
Published: (2026)

Stachydrine represses the proliferation and enhances cell cycle arrest and apoptosis of breast cancer cells via PLA2G2A/DCN axis
by: Zhen Zhai, et al.
Published: (2024)

IGF2BP3 loss inhibits cell progression by upregulating has_circRNA_103820, and hsa_circRNA_103820‐encoded peptide inhibits cell progression by inactivating the AKT pathway in lung cancer
by: Jinrong Zhou, et al.
Published: (2024)

Structure‐Based Design of 2‐Aminopyrazolpyrimidopyridone Derivatives as New Rearranged During Transfection (RET) Kinase Inhibitors
by: Jiayi Shen, et al.
Published: (2024)

Baicalin inhibits monosodium urate crystal‐induced pyroptosis in renal tubular epithelial cell line through Panx‐1/P2X7 pathways: Molecular docking, molecular dynamics, and in vitro experiments
by: Wanting Fu, et al.
Published: (2024)

Prediction of Breast Cancer Lymph Node Metastasis by a Nomogram Model Integrating Pathomics, Radiomics, and Immunoscore
by: Tian Xu, et al.
Published: (2026)

EGFR degraders in non‐small‐cell lung cancer: Breakthrough and unresolved issue
by: Jiayi Shen, et al.
Published: (2024)

Baicalin alleviates oxygen–glucose deprivation/reoxygenation‐induced SK‐N‐SH cell injury via the regulation of miR‐556‐3p/ACSL4 pathway
by: Weiwei Dai, et al.
Published: (2024)

Pharmacophore‐Based Identification and Molecular Characterization of Potent Neprilysin Inhibitors: Biochemical and Therapeutic Implications for Cardiovascular Diseases
by: Chung‐Ting Kuo, et al.
Published: (2026)

Synthesis and SAR investigation of biphenylaminoquinoline derivatives with benzyloxy substituents as promising anticancer agents
by: Yu‐Chieh Wu, et al.
Published: (2024)

Design and Synthesis of 2‐Aminopyrazolpyrimidopyridone Derivatives as RET V 804 M and RET G 810 C Kinase Inhibitors
by: Jiayi Shen, et al.
Published: (2025)

Plumbagin Triggers STING Pathway Activation to Suppress Non‐Small Cell Lung Cancer Progression
by: Li‐Ping Kang, et al.
Published: (2025)

Synthesis of Salidroside Derivatives at C4 Position of Benzene Ring and Its Effect on Hep3B Cell Viability
by: Juntao Wang, et al.
Published: (2025)

Paeoniflorin Alleviates Pulmonary Arterial Hypertension by Suppressing TRIM24 ‐Mediated SIRT1 Ubiquitination and NLRP3 Inflammasome Activation
by: Jinbo Zhang, et al.
Published: (2026)

Dehydroepiandrosterone‐α‐2‐Deoxyglucoside Exhibits Enhanced Anticancer Effects in MCF‐7 Breast Cancer Cells and Inhibits Glucose‐6‐Phosphate Dehydrogenase Activity
by: Hsu‐Feng Liu, et al.
Published: (2024)

Identification and Biological Evaluation of ( 4 H ‐Thieno[3,2‐ b ]indol‐3‐yl)methanol as a Tumoricidal Scaffold for an Antineoplastic Agent
by: Shi‐Hong Zhuang, et al.
Published: (2025)

Knowledgebase‐Driven Exploration and Experimental Verification of Simvastatin's Inhibitory Impact on P2X7/NLRP3 Inflammasome Pathway
by: Xinhai Wu, et al.
Published: (2025)

Using Network Pharmacology and Transcriptome Sequencing to Investigate the Mechanism of Action of Luteolin and Quercetin in Treating Obesity
by: Ruoshuang Liu, et al.
Published: (2025)

Hepatocellular Carcinoma Cells in Humans Exhibit Resistance to Suberoylanilide Hydroxamic Acid (SAHA) Owing to the Diminished Level of Hsa‐miR‐125a‐5p
by: Shih‐Wen Kao, et al.
Published: (2025)

Synthesis, Cytotoxic Activity, and Molecular Docking Study of New Thiazole‐Incorporated Indenopyridazine Derivatives as Potential Antiproliferative Drugs
by: Alaa M. Alqahtani, et al.
Published: (2025)