Multiomics Analyses Demonstrate the Attenuation of Metabolic Cardiac Disorders Associated With Type 2 Diabetes by Stachydrine in Relation With the Transition of Gastrointestinal Microbiota

Dettagli Bibliografici
Autori principali:	Chaoxing Yang, Huaping Zhong
Natura:	Artículo Open Access
Pubblicazione:	Wiley 2025
Soggetti:	Chemical Biology & Drug Design
Accesso online:	Acceder al recurso
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!

Stachydrine represses the proliferation and enhances cell cycle arrest and apoptosis of breast cancer cells via PLA2G2A/DCN axis
di: Zhen Zhai, et al.
Pubblicazione: (2024)

Apelin‐13's Actions in Controlling Hypertension‐Related Cardiac Hypertrophy and the Expressions of Inflammatory Cytokines
di: Xiaoliang Wei, et al.
Pubblicazione: (2024)

Acacetin Attenuates Heatstroke‐Induced Acute Liver Injury by Targeting the c‐Jun/ PTGS2 Pathway
di: Xiaolong Shu, et al.
Pubblicazione: (2026)

Tetrahydropalmatine Alleviates Osteoarthritis‐Associated Pain and Inflammation by Suppressing KDM4A / MDM2 / HIF ‐1α‐Mediated M1 Macrophage Polarization
di: Xiaobo Chen, et al.
Pubblicazione: (2026)

Glutamine Attenuates Inflammation and Oxidative Stress in Ulcerative Colitis by Suppressing Wilms' Tumor 1 Associated Protein‐Mediated N6‐Methyladenosine Modification of Nuclear Receptor Coactivator 3
di: Liangxian Jiang, et al.
Pubblicazione: (2025)

Rutaecarpine Attenuates Ovalbumin‐Induced Asthma in Mice by Regulating the NF ‐ κB Pathway
di: Kongbo Chen, et al.
Pubblicazione: (2026)

Edaravone Ameliorate Inflammation in Vitamin D3 and High Fat Diet Induced Atherosclerosis in Rat via Alteration of Inflammatory Pathway and Gut Microbiota
di: Lingjuan Du, et al.
Pubblicazione: (2024)

Computational Based Identified EAAT2 Transporter Activator Attenuates Amyloid‐β Induced Excitotoxicity in Primary Neuronal‐Astroglial Mixed Culture by Ameliorating Glutamate Clearance
di: Chennu Manisha, et al.
Pubblicazione: (2026)

N‐Substituted‐5‐ [(2,5‐Dihydroxybenzyl)amino]salicylamides as Lavendustin Analogs: Antiproliferative Activity, COMPARE Analyses, Mechanistic, Docking, ADMET and Toxicity Studies
di: Hajjaj H. M. Abdu‐Allah, et al.
Pubblicazione: (2025)

Herbacetin Inhibits Human Fructose 1,6‐Bisphosphatase Among a Panel of Chromone Derivatives and Pyrazoles, Demonstrating Positive Effects on Insulin‐Resistant HepG2 Cells
di: Sónia Rocha, et al.
Pubblicazione: (2024)

Targeting Cancer Cell Proliferation Using Piperazine‐Linked Quinolinequinones: Mechanism and Metabolic Profile
di: Ayse Mine Yilmaz, et al.
Pubblicazione: (2025)

The Immuno‐Metabolic Crosstalk in Lung Squamous Cell Carcinoma: Prognostic Insights and Therapeutic Clues
di: Haoyuan Xue, et al.
Pubblicazione: (2026)

An AI ‐Guided Structure‐Based Strategy for the Discovery and Biological Validation of Natural Products Targeting the Vitamin D Receptor From YSQYP in Diabetic Kidney Disease
di: Xinze Liu, et al.
Pubblicazione: (2026)

Transition metal complexes of hydrazones as potential antimicrobial and anticancer agents: A short review
di: Izabela Czyżewska, et al.
Pubblicazione: (2024)

Crocin enhances the sensitivity to paclitaxel in human breast cancer cells by reducing BIRC5 expression
di: Yunhao Jia, et al.
Pubblicazione: (2024)

Artesunate Suppresses the Migration and Invasion of Thyroid Cancer Cells via Upregulating PTEN to Block M2 Polarization of Tumor‐Associated Macrophages
di: Zhiwei Xu, et al.
Pubblicazione: (2025)

Multi‐Omics and Machine Learning‐Driven Discovery of ABCC8 ( SUR1 ) for Diabetes Mellitus: Integrating Molecular Insights on Nigella sativa Bioactives and Sulfonylurea
di: Mohd Adnan, et al.
Pubblicazione: (2026)

Integrative Multi‐Omics Analysis Identifies FTO as a Genetic and Epigenetic Link Between Metabolic Susceptibility and Staphylococcus aureus ‐Induced Airway Remodeling in Chronic Rhinosinusitis
di: Xinjie Qiao, et al.
Pubblicazione: (2026)

Morusin Reverses Epithelial‐Mesenchymal Transition in Gallbladder Cancer Cells by Regulating STAT3/HIF‐1α Signaling
di: Lichao Ji, et al.
Pubblicazione: (2025)

Kisspeptin‐10 Improves Gestational Diabetes Mellitus Symptoms in Rats by Suppressing Insulin Resistance in Placental Trophoblast Cells by Activating the Cyclic AMP/Protein Kinase A Pathway
di: Jianhua Li, et al.
Pubblicazione: (2025)

Erianin Protects Human Umbilical Vein Endothelial Cells From Oxidized Low‐Density Lipoprotein‐Induced Apoptosis and Oxidative Stress Through Activation of Nuclear Factor E2‐Related Factor 2 Signaling
di: Zhaowei Wang, et al.
Pubblicazione: (2025)

Icariin alleviates the apoptosis of chondrocytes in osteoarthritis through regulating SIRT‐1‐Nrf2‐HO‐1 signaling
di: Ying‐song Liu, et al.
Pubblicazione: (2024)

Identification of Mitophagy‐Related Genes With Diagnostic Value in Atherosclerosis Using Bioinformatics Analysis and Experiment Validation
di: Zhe Chen, et al.
Pubblicazione: (2026)

Procyanidin Alleviates Diabetic Retinopathy by Activating the Expression of Activating Transcription Factor 1 Expression to Upregulate Synoviolin 1 and Inhibit the High Mobility Group Box 1/Toll‐Like Receptor 4 Pathway
di: Limin Zheng, et al.
Pubblicazione: (2025)

Identification of Autophagy‐Associated Molecular Signatures in Osteoarthritis Revealed by Integrative Multi‐Omics and Experimental Validation
di: Xiaoqing Wang, et al.
Pubblicazione: (2026)

Embelin Elevates Endoplasmic Reticulum Calcium Levels and Blocks the Sterol Regulatory Element‐Binding Protein 2 Mediated Proprotein Convertase Subtilisin/Kexin Type 9 Expression and Improves the Low‐Density Lipoprotein Receptor Mediated Lipid Clearance on Hepatocytes
di: Mahesh Chandran, et al.
Pubblicazione: (2025)

EXPRESSION OF CONCERN : The Truncated Human Telomeric Sequence Forms a Hybrid‐Type Intramolecular Mixed Parallel/antiparallel G‐quadruplex Structure in K+ Solution
Pubblicazione: (2024)

Quercetin Prevents Hyperuricemia Associated With Gouty Arthritis by Inactivating the NLRP3/NF‐κB Signaling Pathway
di: Qingliang Meng, et al.
Pubblicazione: (2025)

Ferulic Acid Inhibits Partial Epithelial‐Mesenchymal Transition in Renal Tubular Epithelial Cells and Mitigates Renal Interstitial Fibrosis by Regulating the HIF‐1α/Twist Signaling Pathway
di: Lin Xu, et al.
Pubblicazione: (2025)

Relaxin‐2 Alleviates Hyperoxia‐Induced Acute Lung Injury in Neonatal Rats by Inhibiting TLR4/NF‐κB
di: Mei Yang, et al.
Pubblicazione: (2025)

Hydromorphone hydrochloride preconditioning combined with postconditioning attenuates myocardial ischemia/reperfusion injury in rats by improving mitochondrial function and activating the PI3K/Akt signaling pathway
di: Liuji Qiu, et al.
Pubblicazione: (2024)

Improving Lung Injury in Sepsis‐Related Systemic Inflammatory Response Syndrome Through Regulation of the TLR4 / NF ‐ κB Pathway and Macrophage Polarization by Ganoderic Acid A
di: Mingjie Zhu, et al.
Pubblicazione: (2025)

Asiatic acid inhibits rheumatoid arthritis fibroblast‐like synoviocyte growth through the Nrf2/HO‐1/NF‐κB signaling pathway
di: Li Zhang, et al.
Pubblicazione: (2024)

Brusatol Exerts Therapeutic Effects in Ulcerative Colitis by Regulating the UBE 3 A ‐ LCN 2‐Mediated Ferroptosis and Inflammation Axis
di: Xingzhuo Guan, et al.
Pubblicazione: (2025)

Curculigoside Induces Ferroptosis in Non‐Small Cell Lung Cancer Cells Through a Mechanism Involving Wilms' Tumor 1‐Associating Protein‐Mediated m6A Modification of GTP Cyclohydrolase 1
di: Lizheng Lv, et al.
Pubblicazione: (2026)

Molecular Mechanism of Dexmedetomidine in Alzheimer's Disease: Machine Learning Identifies RGS7 as a Key Therapeutic Targe
di: Yangliang Yang, et al.
Pubblicazione: (2025)

Tanshinone IIA Reverses Osteogenic Differentiation of Bone Marrow Mesenchymal Stromal Cells Impaired by Glucocorticoids via the ERK1/2‐CREB Signaling Pathway
di: Xiaodong Li, et al.
Pubblicazione: (2025)

Remimazolam attenuates inflammation in bronchopneumonia through the inhibition of NLRP3 activity by PDPK1 ubiquitination
di: Min Yang, et al.
Pubblicazione: (2024)

Echinacoside Alleviates Carbon Tetrachloride‐Induced Chronic Liver Injury by Modulating the NF‐κB/NLRP3 Inflammasome Pathway
di: Ye‐jun Yang, et al.
Pubblicazione: (2024)

Curcumin Regulates Microglia Polarization to Alleviate Ischemic Stroke by Targeting microRNA‐205‐5p/Kruppel‐Like Factor 2 (KLF2)/Activating Transcription Factor 2 (ATF2) Axis
di: Xiangyu Cao, et al.
Pubblicazione: (2025)

Documenti analoghi

Documenti analoghi