Buchumschlag

Deep Learning for Drug–Target Interaction Prediction: A Comprehensive Review

Fuente: Wiley Open Access

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	Yingjun Chen, Ding Luo, Weiwei Xue
Format:	Artículo Open Access
Veröffentlicht:	Wiley 2025
Schlagworte:	Chemical Biology & Drug Design
Online-Zugang:	Acceder al recurso
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge

Smart Immunoliposome‐Based Targeted Drug Delivery for Cancer: A Comprehensive Systematic Review
von: Gandhali Ghaisas, et al.
Veröffentlicht: (2026)

A Comprehensive Review on the Advancements of Dual COX‐2/5‐LOX Inhibitors as Anti‐Inflammatory Drugs
von: Neetu Agrawal
Veröffentlicht: (2025)

Transformer‐Based Model for Drug Design and Therapy Response Prediction
von: Zheng Gu, et al.
Veröffentlicht: (2025)

Prediction of Drug‐Induced Liver Injury: From Molecular Physicochemical Properties and Scaffold Architectures to Machine Learning Approaches
von: Yulong Zhao, et al.
Veröffentlicht: (2024)

Targeting the Autophagy–Apoptosis Axis in Osteosarcoma: Therapeutic Potential of Biocompounds: A Review
von: Oznur Bayraktar Ekmekcigil, et al.
Veröffentlicht: (2026)

Repurposing of FDA ‐Approved Drugs to Disrupt Iron Uptake in Mycobacterium abscessus : Targeting Salicylate Synthase as a Novel Approach
von: Giovanni Stelitano, et al.
Veröffentlicht: (2025)

Correction to “Targeting the Autophagy–Apoptosis Axis in Osteosarcoma: Therapeutic Potential of Biocompounds: A Review”
Veröffentlicht: (2026)

Reviewing the IDH1 Mutation‐Mediated Mechanism of Drug Resistance and Revisiting Its Overcoming Strategies
von: Yifan Wang, et al.
Veröffentlicht: (2025)

Old Drug, New Opportunity: Drug Repurposing in Cardiovascular Diseases
von: Xiuyi Ou, et al.
Veröffentlicht: (2026)

In Silico Exploration of Potential Inhibitors Targeting SARS ‐ CoV ‐2 Non‐Structural Protein 15 (Nsp15): A Comprehensive Overview of Current Research
von: Behnaz Yazdani, et al.
Veröffentlicht: (2025)

Synthesis, Biological Assay, and SAR of Potential Anticancer Lipophilic Fluoroquinolones ( FQs ) and Pyridoquinoxalines ( PQs ) Conjugated to Gold Nanoparticles for Synergistic and Proapoptogenic Cytotoxicity Drug Design and Targeted Delivery
von: Alaa Tabaza, et al.
Veröffentlicht: (2025)

A Comprehensive Analysis on Galantamine Based Hybrids for the Management of Alzheimer's Disease
von: Yash Pal Singh, et al.
Veröffentlicht: (2024)

Thienopyrimidine: Unveiling the Versatile Potential of a Promising Heterocyclic Scaffold in Drug Discovery
von: Sahaya Nadar, et al.
Veröffentlicht: (2025)

Tetramethylpyrazine Targets HDAC6 ‐Mediated PINK1 Degradation to Alleviate Chronic Intermittent Hypoxia‐Induced Injury in Human Bronchial Epithelial Cells ( 16HBE )
von: Yanjie Chen, et al.
Veröffentlicht: (2026)

Computationally Guided Structural Modification of Centaureidin: A Novel Approach for Enhancing Antioxidant and Antitumor Activities for Drug Development
von: Reem S. Alruhaimi, et al.
Veröffentlicht: (2025)

Machine Learning‐Based Discovery of a Novel Noncovalent MurA Inhibitor as an Antibacterial Agent
von: Qingxin Liu, et al.
Veröffentlicht: (2025)

Acacetin Attenuates Heatstroke‐Induced Acute Liver Injury by Targeting the c‐Jun/ PTGS2 Pathway
von: Xiaolong Shu, et al.
Veröffentlicht: (2026)

Sulfonyl Hydrazone Derivatives Targeting Glutathione Reductase: A Potential Strategy for Redox Modulation in Cancer
von: Erbay Kalay, et al.
Veröffentlicht: (2025)

Attempts to Achieve Targeted Covalent Inhibition of Hsp90 β
von: Terin D'Amico, et al.
Veröffentlicht: (2026)

Pioneering QSAR Modeling Study of FAP ‐Targeting Radiopharmaceuticals Used in Oncology
von: Dorrin Fatehi, et al.
Veröffentlicht: (2025)

Targeting Poly (ADP‐Ribose) Polymerase‐1 for the Treatment of Neurodegenerative Diseases
von: Shahrazad Polk, et al.
Veröffentlicht: (2025)

Baicalein Targets MAPK9 to Induce Apoptosis of Hepatocellular Carcinoma Cells
von: Weili Wang, et al.
Veröffentlicht: (2024)

Synthesis, Cytotoxic Activity, and Molecular Docking Study of New Thiazole‐Incorporated Indenopyridazine Derivatives as Potential Antiproliferative Drugs
von: Alaa M. Alqahtani, et al.
Veröffentlicht: (2025)

Synthesis and Investigation of Peptide–Drug Conjugates Comprising Camptothecin and a Human Protein‐Derived Cell‐Penetrating Peptide
von: Isabella R. Palombi, et al.
Veröffentlicht: (2025)

Fused and Substituted Piperazines as Anticancer Agents: A Review
von: Saumya Singh, et al.
Veröffentlicht: (2025)

Baicalin alleviates oxygen–glucose deprivation/reoxygenation‐induced SK‐N‐SH cell injury via the regulation of miR‐556‐3p/ACSL4 pathway
von: Weiwei Dai, et al.
Veröffentlicht: (2024)

Antiproliferative Activity and Target Analysis of 18β‐Glycyrrhetinic Acid Derivatives Modified With α, β‐Unsaturated Carbonyl Groups
von: Chenmeng Xu, et al.
Veröffentlicht: (2025)

Thalidomide suppresses migration and invasion of colorectal cancer cells by inhibiting HOXB7‐mediated activation of the Wnt/β‐catenin signaling pathway
von: Liyang Liu, et al.
Veröffentlicht: (2024)

Correction to “Synthesis, Cytotoxic Activity, and Molecular Docking Study of New Thiazole‐Incorporated Indenopyridazine Derivatives as Potential Antiproliferative Drugs”
Veröffentlicht: (2025)

Structural Insights Into Papain‐Derived Synthetic Antibacterial Peptides for Targeting Klebsiella pneumoniae
von: Marcos Antônio Ferreira, et al.
Veröffentlicht: (2025)

Identification of Potential PBP2a Inhibitors Against Methicillin‐Resistant Staphylococcus aureus via Drug Repurposing and Combination Therapy
von: Fangfang Jiao, et al.
Veröffentlicht: (2025)

Isoxazole and Pyrazole Derivatives of 28‐Oxo‐Allobetulone Target Viral Membrane Glycoprotein Hemagglutinin
von: Irina E. Smirnova, et al.
Veröffentlicht: (2025)

Targeting Cancer Cell Proliferation Using Piperazine‐Linked Quinolinequinones: Mechanism and Metabolic Profile
von: Ayse Mine Yilmaz, et al.
Veröffentlicht: (2025)

Pyrrole‐Tethered Bisbenzoxazole Derivatives: Apoptosis‐Inducing Agents Targeting Breast Cancer Cells
von: Burak Kuzu, et al.
Veröffentlicht: (2025)

Investigating the Role of Quercetin, an Active Ingredient in Bazhen Decoction, in Targeting CXCL8 to Inhibit Macrophage M2 Polarization and Reshape the Immunological Microenvironment of Colorectal Cancer
von: Wenwu Wang, et al.
Veröffentlicht: (2025)

Small Molecule Inhibitors Targeting Cdc2‐Like Kinase 4: Advances, Challenges, and Opportunities
von: Yu Jiang, et al.
Veröffentlicht: (2025)

Polyphyllin VII Enhances the Sensitivity of Prostate Cancer Cells to Docetaxel by Promoting Mitochondrial Dysfunction and Inducing Ferroptosis
von: Yun‐Yi Chen, et al.
Veröffentlicht: (2025)

Mitotic Arrest Deficient 2 Like 1 Contributes to Colorectal Cancer Cell Migration, Invasion, and Oxaliplatin Resistance Through the Wnt/β‐Catenin Pathway
von: Xiang Ding, et al.
Veröffentlicht: (2024)

99mTc‐HYNIC PEGylated Peptide Probe Targeting HER2‐Expression in Breast Cancer
von: Sushree Arpitabala Yadav, et al.
Veröffentlicht: (2025)

From Virtual Screening to Cell Phenotype: 4‐Thiazolidone Scaffolds Targeting LOXL2 in Breast Cancer
von: Sandra Ferreira, et al.
Veröffentlicht: (2026)