Image de couverture de livre

In Silico and In Vitro Identification of New Eugenol Derivatives as Inhibitors of the Spike SARS ‐ CoV ‐2 Protein Interaction With the ACE2 Host Receptor

Fuente: Wiley Open Access

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Timoteo Delgado‐Maldonado, Alonzo González‐González, Adriana Moreno‐Rodríguez, Guadalupe Rojas‐Verde, Alma D. Paz‐Gonzalez, Debasish Bandyopadhyay, Gildardo Rivera
Format:	Artículo Open Access
Publié:	Wiley 2025
Sujets:	Chemical Biology & Drug Design
Accès en ligne:	Acceder al recurso
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

Ligand‐Based Pharmacophore Modeling and Structure‐Based Virtual Screening for Identifying Potential Therapeutic Agents Targeting the SARS‐CoV‐2 Spike Protein‐ACE2 Receptor Interaction
par: Timoteo Delgado‐Maldonado, et autres
Publié: (2026)

In Silico Exploration of Potential Inhibitors Targeting SARS ‐ CoV ‐2 Non‐Structural Protein 15 (Nsp15): A Comprehensive Overview of Current Research
par: Behnaz Yazdani, et autres
Publié: (2025)

Targeting the Enzymatic Site of Botulinum Neurotoxin Type E With 8‐Hydroxyquinolinol–Based Inhibitors: In Silico, In Vitro, and In Vivo Evaluation
par: Priyanka Sonkar, et autres
Publié: (2025)

Use of Azithromycin Attributable to Acute SARS‐CoV‐2 Infection
par: Carlo Gagliotti, et autres
Publié: (2024)

Exploring Novel Tetrahydropyrimidine and Fused Pyrimidine‐Based Compounds as DHFR Inhibitors and Antimicrobial Agents: Synthesis, In Vitro, In Vivo, and In Silico Studies
par: Menna M. Sherif, et autres
Publié: (2025)

Identification of Metabolites for the Novel 5α‐Reductase Inhibitor Epristeride In Vitro and Its Potential Impact on Doping Testing
par: Zhongquan Li, et autres
Publié: (2025)

Novel Hexahydropyrimidine Derivatives as Potential Neutral Sphingomyelinase 2 Inhibitors: Synthesis, Metal Chelation, and In Silico Studies
par: Ozge Kuyrukcu Ozturk, et autres
Publié: (2026)

Unlocking the Anticancer Potential of New Spirooxindoles via p53‐MDM2/MDMX Dual Inhibition: In Vitro and In Silico Assessments
par: Haidy H. El‐Zoheiry, et autres
Publié: (2026)

Design, Synthesis, In Silico Profiling, and In Vitro Anticancer Assessment of Azine‐Linked Thiazolo[3,2‐a]benzimidazoles as CDK2‐Directed Therapeutic Candidates
par: Mohamed S. M. Ahmed, et autres
Publié: (2026)

Assessment of Antidiarrheal Effect of Oleuropein Through µ‐Oopioid Receptor Interaction Pathway: In Vivo and in Silico Studies
par: Nishat Jahan, et autres
Publié: (2025)

In Vitro and In Silico Assessment of Antileishmanial Potential of Novel Tri‐ and Penta‐Valent Antimony Complexes With Phenolic Ligands
par: Syeda Aaliya Shehzadi, et autres
Publié: (2025)

Waxy‐ or Putty‐Like Materials as a Novel Drug Preparation for Synthetic Cannabinoid Receptor Agonists: Detection in Prisons and In Vitro Cannabinoid Receptor Activity
par: Axelle Timmerman, et autres
Publié: (2024)

Evaluation of Pyrrolone‐Fused Benzosuberene MK2 Inhibitors as Promising Therapeutic Agents for HNSCC: In Vitro Efficacy, In‐Vivo Safety, and Pharmacokinetic Profiling
par: Prince Anand, et autres
Publié: (2025)

Investigation of the In Vitro and In Vivo Metabolism and μ‐Opioid Receptor Affinity of the Nitazene N ‐Pyrrolidino Fluetonitazene
par: Severin Zemp, et autres
Publié: (2026)

Exploring the Analgesic and Antidiarrheal Properties of Angelicin Through Cyclooxygenase Inhibition and Μ‐Opioid Receptor Interaction: In Vivo and In Silico Studies
par: Sourav Bagchi, et autres
Publié: (2025)

Development of Quinoline‐Isoxazole Hybrids With Selective Cytotoxicity and EGFR Kinase Binding: In Vitro and In Silico Approaches
par: Yasemin Zeynep Şahin, et autres
Publié: (2025)

Structure‐Guided Design and Mechanistic Elucidation of New Chromene Derivatives as Selective Vascular Endothelial Growth Factor Receptor‐2 Inhibitors With Potent Anticancer Activity
par: Hazem Elkady, et autres
Publié: (2026)

Repurposing Nitroimidazoles: A New Frontier in Combatting Bacterial Virulence and Quorum Sensing via In Silico, In Vitro, and In Vivo Insights
par: El‐Sayed Khafagy, et autres
Publié: (2025)

Identification and Investigation of the Intrinsic Receptor Activation Potential and Metabolization of the New Oxo‐Pyridyl Synthetic Cannabinoid Receptor Agonist CH‐FUBBMPDORA
par: Marie H. Deventer, et autres
Publié: (2025)

Identification of Potent Leucine‐Rich Repeat Kinase 2 Inhibitors by Virtual Screening and Biological Evaluation
par: Hualiang Shen, et autres
Publié: (2025)

Piperidine‐Based Hydrazones and Their Pt(II)/Pd(II) Complexes: Synthesis, Structural Characterization, In Vitro Anticancer Evaluation, and In Silico Studies
par: Muhammed Oğuzhan Doğan, et autres
Publié: (2026)

Molecular Boomerangs Against Cancer: Design, Synthesis, Biological Evaluation, and In Silico Study of Novel Dual PARP‐1/EGFR Inhibitors
par: Haytham O. Tawfik, et autres
Publié: (2026)

Gel Electrophoretic Detection of Black Market ACE‐031
par: Christian Reichel, et autres
Publié: (2025)

Elucidation of the Microwave‐Assisted Synthesis and Characterization of Heteronuclear Complexes of Bisbenzimidazole Derivatives and Their Biological Activities by In Vitro and In Silico Assays
par: Esra Kaplan, et autres
Publié: (2024)

Coumarin Analogues as Promising Anti‐Obesity Agents: In Silico Design, Synthesis, and In Vitro Pancreatic Lipase Inhibitory Activity
par: Nisha Yadav, et autres
Publié: (2025)

Multifaceted In Silico Screening Strategies Identifies Potent Inhibitors Facilitating Inhibition of ZNF726 Activity in Breast Cancer
par: Shreetama Bandyopadhayaya, et autres
Publié: (2025)

Safety, Tolerability, and Pharmacokinetics of the Long‐Acting SARS‐CoV‐2–Neutralizing Monoclonal Antibody Combination AZD7442 (Tixagevimab/Cilgavimab) in Healthy Chinese Adults
par: Nanyang Li, et autres
Publié: (2025)

Discovery of Novel 1,3,5‐trisubstituted‐2‐thioxo‐imidazole Derivatives as Potential Aromatase Inhibitors: Design, Synthesis, In Vitro Anti‐Breast Cancer Screening and Molecular Docking Studies
par: Mohamed F. Youssef, et autres
Publié: (2026)

Heteromerization, Biased Agonism, and Allosteric Modulation of G Protein‐Coupled Receptors in Addiction: Mechanistic Insights and Therapeutic Implications
par: Khaled A. Alhosaini, et autres
Publié: (2026)

Characterization of SARS‐CoV‐2 Diagnostic Tests and Liver Function Tests Among Patients With COVID‐19 Diagnosed in Outpatient Settings Using Administrative Healthcare Data and Data From Commercial Laboratories
par: Ayad K. Ali, et autres
Publié: (2025)

Novel 4‐chlorophenyl and 3/4‐chlorophenoxy Based Triazole/Thiazole Derivatives: Synthesis and Investigation of Their Effects on Neurodegenerative Disorders‐Related Enzymes via In Vitro and In Silico
par: Sam Dawbaa, et autres
Publié: (2025)

Identification of Potential PBP2a Inhibitors Against Methicillin‐Resistant Staphylococcus aureus via Drug Repurposing and Combination Therapy
par: Fangfang Jiao, et autres
Publié: (2025)

SGLT2 Inhibitors and GLP‐1 Receptor Agonists After Acute Kidney Injury: A Systematic Review With Meta‐Analysis
par: Erin F. Barreto, et autres
Publié: (2026)

Pyrimidine‐Derived Scaffolds Targeting VEGFR‐2, EGFR, and HER‐2: Synthesis, Anticancer/Immunomodulatory Evaluation, and In Silico Analysis
par: Naglaa M. Ahmed, et autres
Publié: (2026)

Augmenting the Anti‐Leukemic Activity of the BCL‐2 Inhibitor Venetoclax Through Its Transformation Into Polypharmacologic Dual BCL‐2/HDAC1 and Dual BCL‐2/HDAC6 Inhibitors
par: Alexandria M. Chan, et autres
Publié: (2025)

Protein Kinase Inhibitors: Synthesis and Molecular Repurposing in Three‐Dimensional Cancer Models PKI
par: Vladislav Lobanov, et autres
Publié: (2025)

Predictors of Discontinuation of Angiotensin Converting Enzyme Inhibitors Use Among Medicare Beneficiaries Using Sodium‐Glucose Cotransporter 2 Inhibitors
par: Hongjie Qian, et autres
Publié: (2026)

Pharmacological reprogramming of plitidepsin as a SARS-CoV-2 inhibitor.
par: Jimeno, Jose, et autres
Publié: (2025)

RPIS_FragmentationLibraries: Molecular Fragments Useful for Design of Molecular Glues for Protein-RNA complexes
par: Luis Vollmers, et autres
Publié: (2026)

Temporal Trend in Selective Cyclooxygenase‐2 Inhibitors Sales in Brazilian Drugstores
par: Tayanny Margarida Menezes Almeida Biase, et autres
Publié: (2025)