Symmetrical drug‐related intertriginous and flexural exanthema (SDRIFE) after administration of corticosteroids: Case series and review of literature
Fuente:
Wiley Open Access
Salvato in:
| Autori principali: | , , , , |
|---|---|
| Natura: | Artículo Open Access |
| Pubblicazione: |
Wiley
2024
|
| Soggetti: | |
| Accesso online: | |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!
|
| _version_ | 1867002405468504064 |
|---|---|
| author | Julian Steininger Andrea Bauer Helena Hasler Stefan Beissert Susanne Abraham |
| author_facet | Julian Steininger Andrea Bauer Helena Hasler Stefan Beissert Susanne Abraham Julian Steininger Andrea Bauer Helena Hasler Stefan Beissert Susanne Abraham |
| collection | Wiley Open Access |
| contents | Symmetrical drug‐related intertriginous and flexural exanthema (SDRIFE) after administration of corticosteroids: Case series and review of literature Julian Steininger Andrea Bauer Helena Hasler Stefan Beissert Susanne Abraham Contact Dermatitis AbstractBackgroundCutaneous manifestations of drug‐induced type IV reactions vary widely, with symmetrical drug‐related intertriginous and flexural exanthema (SDRIFE) being a less common presentation. Corticosteroids (CS), primarily known for their anti‐inflammatory effects, rarely induce hypersensitivity reactions.ObjectiveThe aim of this case series is to report four cases of SDRIFE following systemic prednisolone therapy and to review existing CS classification proposals to better understand cross‐reactivity of CS.Patients/MethodsPatients recruited at a German dermatology centre underwent allergologic evaluation including prick and patch testing with various CS. Positive cases underwent oral challenge testing with alternative agents. The classification systems of Coopman et al. and Baeck et al. were taken into account.DiscussionDespite a paucity of literature, CS‐induced type IV reactions do occur, including SDRIFE. Classification systems based on chemical structure provide insight into cross‐reactivity patterns. Provocation tests with alternative CS highlight the complexity of managing CS hypersensitivity.ConclusionSDRIFE may develop following systemic prednisolone therapy. Classification systems are helpful in understanding cross‐reactivity and help in the selection of alternative preparations but are not always reliable. Individualised assessment is crucial for managing CS hypersensitivity, with consideration of alternative agents and emergency use of CS when necessary. 10.1111/cod.14594 http://creativecommons.org/licenses/by/4.0/ |
| doi_str_mv | 10.1111/cod.14594 |
| format | Artículo Open Access |
| id | wiley_oa_10_1111_cod_14594 |
| institution | Wiley Open Access |
| license_str_mv | http://creativecommons.org/licenses/by/4.0/ |
| publishDate | 2024 |
| publisher | Wiley |
| record_format | wiley_oa |
| spellingShingle | Symmetrical drug‐related intertriginous and flexural exanthema (SDRIFE) after administration of corticosteroids: Case series and review of literature Julian Steininger Andrea Bauer Helena Hasler Stefan Beissert Susanne Abraham Contact Dermatitis Symmetrical drug‐related intertriginous and flexural exanthema (SDRIFE) after administration of corticosteroids: Case series and review of literature Julian Steininger Andrea Bauer Helena Hasler Stefan Beissert Susanne Abraham Contact Dermatitis AbstractBackgroundCutaneous manifestations of drug‐induced type IV reactions vary widely, with symmetrical drug‐related intertriginous and flexural exanthema (SDRIFE) being a less common presentation. Corticosteroids (CS), primarily known for their anti‐inflammatory effects, rarely induce hypersensitivity reactions.ObjectiveThe aim of this case series is to report four cases of SDRIFE following systemic prednisolone therapy and to review existing CS classification proposals to better understand cross‐reactivity of CS.Patients/MethodsPatients recruited at a German dermatology centre underwent allergologic evaluation including prick and patch testing with various CS. Positive cases underwent oral challenge testing with alternative agents. The classification systems of Coopman et al. and Baeck et al. were taken into account.DiscussionDespite a paucity of literature, CS‐induced type IV reactions do occur, including SDRIFE. Classification systems based on chemical structure provide insight into cross‐reactivity patterns. Provocation tests with alternative CS highlight the complexity of managing CS hypersensitivity.ConclusionSDRIFE may develop following systemic prednisolone therapy. Classification systems are helpful in understanding cross‐reactivity and help in the selection of alternative preparations but are not always reliable. Individualised assessment is crucial for managing CS hypersensitivity, with consideration of alternative agents and emergency use of CS when necessary. 10.1111/cod.14594 http://creativecommons.org/licenses/by/4.0/ |
| title | Symmetrical drug‐related intertriginous and flexural exanthema (SDRIFE) after administration of corticosteroids: Case series and review of literature |
| topic | Contact Dermatitis |
| url | https://onlinelibrary.wiley.com/doi/10.1111/cod.14594 |