Results of Concurrent Patch Testing of Brazilian and Chinese Propolis

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Hauptverfasser: Emma M. van Oers, Norbertus A. Ipenburg, Anton de Groot, Evelyn Calta, Thomas Rustemeyer
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Veröffentlicht: Wiley 2024
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author Emma M. van Oers
Norbertus A. Ipenburg
Anton de Groot
Evelyn Calta
Thomas Rustemeyer
author_facet Emma M. van Oers
Norbertus A. Ipenburg
Anton de Groot
Evelyn Calta
Thomas Rustemeyer
Emma M. van Oers
Norbertus A. Ipenburg
Anton de Groot
Evelyn Calta
Thomas Rustemeyer
collection Wiley Open Access
contents Results of Concurrent Patch Testing of Brazilian and Chinese Propolis Emma M. van Oers Norbertus A. Ipenburg Anton de Groot Evelyn Calta Thomas Rustemeyer Contact Dermatitis ABSTRACT Background In Amsterdam, a steep increase in positive reactions to propolis in the European baseline series was observed from 2.8% in 2020 to 16.4% in 2023. We hypothesised that this was caused by the replacement of Chinese propolis by Brazilian propolis. Objectives To test this hypothesis and to compare rates of positive patch tests to Brazilian propolis with those to Chinese popolis. Patients and Methods In a prospective study, 2 commercial Chinese propolis patch test samples were tested in consecutive patients in addition to Brazilian propolis. Results Of 239 patients patch tested, 57 (23.8%) had a positive reaction to Brazilian propolis, and 9 (3.8%) to Chinese propolis. Of the 57 reactions to Brazilian propolis, only 2 (3.5%) were found to be clinically relevant, versus 3/9 (33.3%) for Chinese propolis. Patients reacting to Brazilian propolis had significantly more co‐reactivities to fragrance mixes 1 and 2 and to limonene hydroperoxides than propolis B‐negative individuals. Conclusions The results confirm our hypothesis that the observed increase in positive patch tests to propolis between 2020 and 2023 was the result of the switch from Chinese to Brazilian propolis. The rates of reactions to both propolis samples from China were significantly lower than to Brazilian propolis. 10.1111/cod.14748 http://creativecommons.org/licenses/by-nc-nd/4.0/
doi_str_mv 10.1111/cod.14748
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publisher Wiley
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spellingShingle Results of Concurrent Patch Testing of Brazilian and Chinese Propolis
Emma M. van Oers
Norbertus A. Ipenburg
Anton de Groot
Evelyn Calta
Thomas Rustemeyer
Contact Dermatitis
Results of Concurrent Patch Testing of Brazilian and Chinese Propolis Emma M. van Oers Norbertus A. Ipenburg Anton de Groot Evelyn Calta Thomas Rustemeyer Contact Dermatitis ABSTRACT Background In Amsterdam, a steep increase in positive reactions to propolis in the European baseline series was observed from 2.8% in 2020 to 16.4% in 2023. We hypothesised that this was caused by the replacement of Chinese propolis by Brazilian propolis. Objectives To test this hypothesis and to compare rates of positive patch tests to Brazilian propolis with those to Chinese popolis. Patients and Methods In a prospective study, 2 commercial Chinese propolis patch test samples were tested in consecutive patients in addition to Brazilian propolis. Results Of 239 patients patch tested, 57 (23.8%) had a positive reaction to Brazilian propolis, and 9 (3.8%) to Chinese propolis. Of the 57 reactions to Brazilian propolis, only 2 (3.5%) were found to be clinically relevant, versus 3/9 (33.3%) for Chinese propolis. Patients reacting to Brazilian propolis had significantly more co‐reactivities to fragrance mixes 1 and 2 and to limonene hydroperoxides than propolis B‐negative individuals. Conclusions The results confirm our hypothesis that the observed increase in positive patch tests to propolis between 2020 and 2023 was the result of the switch from Chinese to Brazilian propolis. The rates of reactions to both propolis samples from China were significantly lower than to Brazilian propolis. 10.1111/cod.14748 http://creativecommons.org/licenses/by-nc-nd/4.0/
title Results of Concurrent Patch Testing of Brazilian and Chinese Propolis
topic Contact Dermatitis
url https://onlinelibrary.wiley.com/doi/10.1111/cod.14748