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| Autores principales: | , , , , , , , |
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| Formato: | Artículo Open Access |
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Wiley
2025
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| Acceso en línea: | https://onlinelibrary.wiley.com/doi/10.1111/cod.14814 |
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- Burden of Pain and Use of Analgesics in Patients With Chronic Hand Eczema—Findings From the Danish Skin Cohort Jeanette Halskou Haugaard Johan Sieborg Emma Guttman‐Yassky David Thein Jonathan I. Silverberg Lars Erik Kristensen Jacob P. Thyssen Alexander Egeberg Contact Dermatitis ABSTRACTBackgroundSkin pain is a common symptom in patients with chronic hand eczema (CHE); however, its association with increased analgesic use has not been thoroughly investigated.ObjectivesTo examine analgesic use (paracetamol, nonsteroidal anti‐inflammatory drugs [NSAIDs], opioids and gabapentin/pregabalin) among patients with CHE compared to a control group.MethodsData were obtained from the Danish Skin Cohort and the Danish national registries. Patients with dermatologist‐verified CHE were systematically interviewed, including questions on skin and joint pain experienced within the past 7 days.ResultsThe study included 1032 patients with CHE and 11 166 controls. We observed an overall higher utilisation of analgesics among patients with CHE compared to the control group. The highest utilisation of analgesics was observed for paracetamol (35.3% vs. 25.7%) followed by NSAIDs (21.5% vs. 15.3%). When stratified by disease severity, patients with moderate‐to‐very‐severe CHE consistently used more analgesics compared to those with mild CHE.ConclusionThis study highlights the significant burden of pain in patients with CHE, as evidenced by their higher utilisation of analgesics compared to the general population in Denmark. 10.1111/cod.14814 http://onlinelibrary.wiley.com/termsAndConditions#vor