Epidemiological, Clinical and Allergic Profile of Patients With Dyshidrotic Eczema (Acute and Recurrent Vesicular Dermatitis): Evaluation of the Spanish Registry of Research in Contact Dermatitis and Cutaneous Allergy ( REIDAC )
Fuente:
Wiley Open Access
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Artículo Open Access |
| Veröffentlicht: |
Wiley
2026
|
| Schlagworte: | |
| Online-Zugang: | |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| _version_ | 1867021884577546240 |
|---|---|
| author | Araceli Sánchez‐Gilo Enrique Gómez de la Fuente Ana M. Giménez‐Arnau Juan Francisco Silvestre‐Salvador Pedro Mercader‐García Tatiana Sanz‐Sánchez Violeta Zaragoza‐Ninet Susana Córdoba‐Guijarro Javier Miquel‐Miquel Ricardo González‐Pérez Inmaculada Ruiz‐Gonzalez Esther Serra‐Baldrich José Manuel Carrascosa‐Carrillo Francisco Javier Ortiz de Frutos Mercedes Rodríguez‐Serna María Elena Gatica‐Ortega Carmen Paredes‐Suárez Francisco J. Navarro‐Triviño Pablo Chicharro María Antonia Pastor‐Nieto Marta Andreu Barasoain José‐Juan Pereyra‐Rodríguez Gemma Melé‐Ninot Paloma Sánchez‐Pedreño Guillén Marta Elosua‐González Miguel Ángel Descalzo Ignacio García‐Doval Raquel Barba‐Martín Leopoldo Borrego |
| author_facet | Araceli Sánchez‐Gilo Enrique Gómez de la Fuente Ana M. Giménez‐Arnau Juan Francisco Silvestre‐Salvador Pedro Mercader‐García Tatiana Sanz‐Sánchez Violeta Zaragoza‐Ninet Susana Córdoba‐Guijarro Javier Miquel‐Miquel Ricardo González‐Pérez Inmaculada Ruiz‐Gonzalez Esther Serra‐Baldrich José Manuel Carrascosa‐Carrillo Francisco Javier Ortiz de Frutos Mercedes Rodríguez‐Serna María Elena Gatica‐Ortega Carmen Paredes‐Suárez Francisco J. Navarro‐Triviño Pablo Chicharro María Antonia Pastor‐Nieto Marta Andreu Barasoain José‐Juan Pereyra‐Rodríguez Gemma Melé‐Ninot Paloma Sánchez‐Pedreño Guillén Marta Elosua‐González Miguel Ángel Descalzo Ignacio García‐Doval Raquel Barba‐Martín Leopoldo Borrego Araceli Sánchez‐Gilo Enrique Gómez de la Fuente Ana M. Giménez‐Arnau Juan Francisco Silvestre‐Salvador Pedro Mercader‐García Tatiana Sanz‐Sánchez Violeta Zaragoza‐Ninet Susana Córdoba‐Guijarro Javier Miquel‐Miquel Ricardo González‐Pérez Inmaculada Ruiz‐Gonzalez Esther Serra‐Baldrich José Manuel Carrascosa‐Carrillo Francisco Javier Ortiz de Frutos Mercedes Rodríguez‐Serna María Elena Gatica‐Ortega Carmen Paredes‐Suárez Francisco J. Navarro‐Triviño Pablo Chicharro María Antonia Pastor‐Nieto Marta Andreu Barasoain José‐Juan Pereyra‐Rodríguez Gemma Melé‐Ninot Paloma Sánchez‐Pedreño Guillén Marta Elosua‐González Miguel Ángel Descalzo Ignacio García‐Doval Raquel Barba‐Martín Leopoldo Borrego |
| collection | Wiley Open Access |
| contents | Epidemiological, Clinical and Allergic Profile of Patients With Dyshidrotic Eczema (Acute and Recurrent Vesicular Dermatitis): Evaluation of the Spanish Registry of Research in Contact Dermatitis and Cutaneous Allergy ( REIDAC ) Araceli Sánchez‐Gilo Enrique Gómez de la Fuente Ana M. Giménez‐Arnau Juan Francisco Silvestre‐Salvador Pedro Mercader‐García Tatiana Sanz‐Sánchez Violeta Zaragoza‐Ninet Susana Córdoba‐Guijarro Javier Miquel‐Miquel Ricardo González‐Pérez Inmaculada Ruiz‐Gonzalez Esther Serra‐Baldrich José Manuel Carrascosa‐Carrillo Francisco Javier Ortiz de Frutos Mercedes Rodríguez‐Serna María Elena Gatica‐Ortega Carmen Paredes‐Suárez Francisco J. Navarro‐Triviño Pablo Chicharro María Antonia Pastor‐Nieto Marta Andreu Barasoain José‐Juan Pereyra‐Rodríguez Gemma Melé‐Ninot Paloma Sánchez‐Pedreño Guillén Marta Elosua‐González Miguel Ángel Descalzo Ignacio García‐Doval Raquel Barba‐Martín Leopoldo Borrego Contact Dermatitis ABSTRACT Background Dyshidrotic eczema (DE), also termed acute and recurrent vesicular dermatitis, is a vesicular clinical pattern of hand eczema (HE) with heterogeneous aetiologies. Objectives To characterise the clinical‐allergological profile of patients with DE and to compare it with non‐DE HE subtypes. Methods A multicentre, retrospective, observational study was conducted using data from the Spanish Contact Dermatitis Registry (2019–2024). Results Of 4378 patients with HE, 559 were diagnosed with DE. A longer median disease duration (24 vs. 14 months) and more frequent palmoplantar involvement (16% vs. 7%) were observed in DE compared with non‐DE HE. At least one positive patch test was identified in 43% of DE versus 52% in non‐DE HE. Although overall sensitisation patterns were largely comparable, DE showed lower sensitisation rates to 2‐HEMA, carba mix and thiuram mix. Occupational factors were less frequently implicated in DE (9% vs. 29%) compared with non‐DE HE. Conclusions Despite a high overall frequency of contact allergen sensitisation, the pattern of findings suggests that the dyshidrotic phenotype may follow a clinical course less dependent on external or occupational triggers, pointing towards a relatively greater contribution of endogenous factors compared with other HE subtypes. 10.1111/cod.70184 http://creativecommons.org/licenses/by/4.0/ |
| doi_str_mv | 10.1111/cod.70184 |
| format | Artículo Open Access |
| id | wiley_oa_10_1111_cod_70184 |
| institution | Wiley Open Access |
| license_str_mv | http://creativecommons.org/licenses/by/4.0/ |
| publishDate | 2026 |
| publisher | Wiley |
| record_format | wiley_oa |
| spellingShingle | Epidemiological, Clinical and Allergic Profile of Patients With Dyshidrotic Eczema (Acute and Recurrent Vesicular Dermatitis): Evaluation of the Spanish Registry of Research in Contact Dermatitis and Cutaneous Allergy ( REIDAC ) Araceli Sánchez‐Gilo Enrique Gómez de la Fuente Ana M. Giménez‐Arnau Juan Francisco Silvestre‐Salvador Pedro Mercader‐García Tatiana Sanz‐Sánchez Violeta Zaragoza‐Ninet Susana Córdoba‐Guijarro Javier Miquel‐Miquel Ricardo González‐Pérez Inmaculada Ruiz‐Gonzalez Esther Serra‐Baldrich José Manuel Carrascosa‐Carrillo Francisco Javier Ortiz de Frutos Mercedes Rodríguez‐Serna María Elena Gatica‐Ortega Carmen Paredes‐Suárez Francisco J. Navarro‐Triviño Pablo Chicharro María Antonia Pastor‐Nieto Marta Andreu Barasoain José‐Juan Pereyra‐Rodríguez Gemma Melé‐Ninot Paloma Sánchez‐Pedreño Guillén Marta Elosua‐González Miguel Ángel Descalzo Ignacio García‐Doval Raquel Barba‐Martín Leopoldo Borrego Contact Dermatitis Epidemiological, Clinical and Allergic Profile of Patients With Dyshidrotic Eczema (Acute and Recurrent Vesicular Dermatitis): Evaluation of the Spanish Registry of Research in Contact Dermatitis and Cutaneous Allergy ( REIDAC ) Araceli Sánchez‐Gilo Enrique Gómez de la Fuente Ana M. Giménez‐Arnau Juan Francisco Silvestre‐Salvador Pedro Mercader‐García Tatiana Sanz‐Sánchez Violeta Zaragoza‐Ninet Susana Córdoba‐Guijarro Javier Miquel‐Miquel Ricardo González‐Pérez Inmaculada Ruiz‐Gonzalez Esther Serra‐Baldrich José Manuel Carrascosa‐Carrillo Francisco Javier Ortiz de Frutos Mercedes Rodríguez‐Serna María Elena Gatica‐Ortega Carmen Paredes‐Suárez Francisco J. Navarro‐Triviño Pablo Chicharro María Antonia Pastor‐Nieto Marta Andreu Barasoain José‐Juan Pereyra‐Rodríguez Gemma Melé‐Ninot Paloma Sánchez‐Pedreño Guillén Marta Elosua‐González Miguel Ángel Descalzo Ignacio García‐Doval Raquel Barba‐Martín Leopoldo Borrego Contact Dermatitis ABSTRACT Background Dyshidrotic eczema (DE), also termed acute and recurrent vesicular dermatitis, is a vesicular clinical pattern of hand eczema (HE) with heterogeneous aetiologies. Objectives To characterise the clinical‐allergological profile of patients with DE and to compare it with non‐DE HE subtypes. Methods A multicentre, retrospective, observational study was conducted using data from the Spanish Contact Dermatitis Registry (2019–2024). Results Of 4378 patients with HE, 559 were diagnosed with DE. A longer median disease duration (24 vs. 14 months) and more frequent palmoplantar involvement (16% vs. 7%) were observed in DE compared with non‐DE HE. At least one positive patch test was identified in 43% of DE versus 52% in non‐DE HE. Although overall sensitisation patterns were largely comparable, DE showed lower sensitisation rates to 2‐HEMA, carba mix and thiuram mix. Occupational factors were less frequently implicated in DE (9% vs. 29%) compared with non‐DE HE. Conclusions Despite a high overall frequency of contact allergen sensitisation, the pattern of findings suggests that the dyshidrotic phenotype may follow a clinical course less dependent on external or occupational triggers, pointing towards a relatively greater contribution of endogenous factors compared with other HE subtypes. 10.1111/cod.70184 http://creativecommons.org/licenses/by/4.0/ |
| title | Epidemiological, Clinical and Allergic Profile of Patients With Dyshidrotic Eczema (Acute and Recurrent Vesicular Dermatitis): Evaluation of the Spanish Registry of Research in Contact Dermatitis and Cutaneous Allergy ( REIDAC ) |
| topic | Contact Dermatitis |
| url | https://onlinelibrary.wiley.com/doi/10.1111/cod.70184 |