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| Natura: | Artículo Open Access |
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Wiley
2025
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| Accesso online: | https://onlinelibrary.wiley.com/doi/10.1111/codi.70185 |
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| _version_ | 1867020871807270912 |
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| author | Jabir Elkrinawi Roba Ganayem Sarah Weissmann Waleed Alamour Zlata Lerner Osama Alamour Abed Abu Ganim Naim Abu‐Freha |
| author_facet | Jabir Elkrinawi Roba Ganayem Sarah Weissmann Waleed Alamour Zlata Lerner Osama Alamour Abed Abu Ganim Naim Abu‐Freha Jabir Elkrinawi Roba Ganayem Sarah Weissmann Waleed Alamour Zlata Lerner Osama Alamour Abed Abu Ganim Naim Abu‐Freha |
| collection | Wiley Open Access |
| contents | Complications of diverticulosis, frequency and risk factors: Results from a large database with long‐term follow‐up Jabir Elkrinawi Roba Ganayem Sarah Weissmann Waleed Alamour Zlata Lerner Osama Alamour Abed Abu Ganim Naim Abu‐Freha Colorectal Disease Abstract Background Diverticulosis of the Colon (DC) is a common finding at colonoscopies. Aims We aimed to investigate the differences between complicated DC (CDC) and uncomplicated DC (UDC) and to explore the risk factors for CDC. Methods We analysed data from a cohort of 149,094 patients, including 123,024 UDC patients and 26,070 CDC patients. Demographics, comorbidities and clinical outcomes were compared. Results Patients with CDC were significantly younger (64.3 ± 15 years vs. 67.5 ± 12.7 years), 55.6% vs. 53.2% females and 8.9% of Arab ethnicity. Smoking was more prevalent in the CDC group (28.2% vs. 26.1%). Diabetes Mellitus and obesity were less prevalent in the CDC group. Treatment with statins (29.2% vs. 40.4%) was also less commonly used in the CDC group. In the multivariate analysis, female gender and smoking were found to be risk factors for CDC (OR 1.215 and OR 1.150, p < 0.001, respectively). Age, Diabetes Mellitus, Obesity, Acetylsalicylic Acid and statin treatment were found to be protective against complications. Conclusions Young age, female sex and smoking were associated with complicated diverticulosis, and uncomplicated diverticulosis seems to be protected by specific diseases. Understanding these differences may help guide risk stratification and improve management strategies for diverticulosis. 10.1111/codi.70185 http://onlinelibrary.wiley.com/termsAndConditions#vor |
| doi_str_mv | 10.1111/codi.70185 |
| format | Artículo Open Access |
| id | wiley_oa_10_1111_codi_70185 |
| institution | Wiley Open Access |
| license_str_mv | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| publishDate | 2025 |
| publisher | Wiley |
| record_format | wiley_oa |
| spellingShingle | Complications of diverticulosis, frequency and risk factors: Results from a large database with long‐term follow‐up Jabir Elkrinawi Roba Ganayem Sarah Weissmann Waleed Alamour Zlata Lerner Osama Alamour Abed Abu Ganim Naim Abu‐Freha Colorectal Disease Complications of diverticulosis, frequency and risk factors: Results from a large database with long‐term follow‐up Jabir Elkrinawi Roba Ganayem Sarah Weissmann Waleed Alamour Zlata Lerner Osama Alamour Abed Abu Ganim Naim Abu‐Freha Colorectal Disease Abstract Background Diverticulosis of the Colon (DC) is a common finding at colonoscopies. Aims We aimed to investigate the differences between complicated DC (CDC) and uncomplicated DC (UDC) and to explore the risk factors for CDC. Methods We analysed data from a cohort of 149,094 patients, including 123,024 UDC patients and 26,070 CDC patients. Demographics, comorbidities and clinical outcomes were compared. Results Patients with CDC were significantly younger (64.3 ± 15 years vs. 67.5 ± 12.7 years), 55.6% vs. 53.2% females and 8.9% of Arab ethnicity. Smoking was more prevalent in the CDC group (28.2% vs. 26.1%). Diabetes Mellitus and obesity were less prevalent in the CDC group. Treatment with statins (29.2% vs. 40.4%) was also less commonly used in the CDC group. In the multivariate analysis, female gender and smoking were found to be risk factors for CDC (OR 1.215 and OR 1.150, p < 0.001, respectively). Age, Diabetes Mellitus, Obesity, Acetylsalicylic Acid and statin treatment were found to be protective against complications. Conclusions Young age, female sex and smoking were associated with complicated diverticulosis, and uncomplicated diverticulosis seems to be protected by specific diseases. Understanding these differences may help guide risk stratification and improve management strategies for diverticulosis. 10.1111/codi.70185 http://onlinelibrary.wiley.com/termsAndConditions#vor |
| title | Complications of diverticulosis, frequency and risk factors: Results from a large database with long‐term follow‐up |
| topic | Colorectal Disease |
| url | https://onlinelibrary.wiley.com/doi/10.1111/codi.70185 |