| _version_ | 1867004251033567232 |
|---|---|
| author | Wolfgang Albert Anita Hudalla Luisa Hensky Aslı Akın Christoph Knosalla Fabian Richter |
| author_facet | Wolfgang Albert Anita Hudalla Luisa Hensky Aslı Akın Christoph Knosalla Fabian Richter Wolfgang Albert Anita Hudalla Luisa Hensky Aslı Akın Christoph Knosalla Fabian Richter |
| collection | Wiley Open Access |
| contents | Quality of Life in Patients 20–31 Years After Heart Transplantation Wolfgang Albert Anita Hudalla Luisa Hensky Aslı Akın Christoph Knosalla Fabian Richter Clinical Transplantation ABSTRACTBackgroundSurvival rates after heart transplantation (HTx) have significantly improved over the last decades. There is a growing need to understand the long‐term psychological and somatic outcomes, which constitute quality of life (QoL), for these long‐term survivors.MethodsThe QoL of patients (N = 75) living 20–31 years (M = 24.9 years, SD = 2.3 years) after orthotopic HTx was evaluated. In a first step, a detailed overview of the patients’ somatic condition was assessed. Secondly, patients were compared to 58 control subjects in terms of self‐reported QoL (SF‐36) and psychological domains (GBB‐24; HADS). Finally, a cluster analysis was conducted to identify patterns within the patient‐reported outcome measures (PROMs) and to relate them to somatic, psychosocial, and demographic variables.Results95.7% of the HTx‐patients were in NYHA functional class I or II, and only 15.2% had a reduced LVEF. Compared to controls, long‐term HTx patients had significantly lower scores on the physical component summary (PCS) of QoL and on the GBB‐24 but not in the mental component summary (MCS) of QoL, or anxiety and depression (HADS). Clustering revealed two distinct groups of patients characterized by high versus low functioning and different levels of social support.ConclusionsLong‐term survivors have a good functional, cardiac, and mental status, but report a lower physical QoL and higher levels of subjective complaints. The importance of social support for HTx recipients is once again highlighted. 10.1111/ctr.15400 http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| doi_str_mv | 10.1111/ctr.15400 |
| format | Artículo Open Access |
| id | wiley_oa_10_1111_ctr_15400 |
| institution | Wiley Open Access |
| license_str_mv | http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| publishDate | 2024 |
| publisher | Wiley |
| record_format | wiley_oa |
| spellingShingle | Quality of Life in Patients 20–31 Years After Heart Transplantation Wolfgang Albert Anita Hudalla Luisa Hensky Aslı Akın Christoph Knosalla Fabian Richter Clinical Transplantation Quality of Life in Patients 20–31 Years After Heart Transplantation Wolfgang Albert Anita Hudalla Luisa Hensky Aslı Akın Christoph Knosalla Fabian Richter Clinical Transplantation ABSTRACTBackgroundSurvival rates after heart transplantation (HTx) have significantly improved over the last decades. There is a growing need to understand the long‐term psychological and somatic outcomes, which constitute quality of life (QoL), for these long‐term survivors.MethodsThe QoL of patients (N = 75) living 20–31 years (M = 24.9 years, SD = 2.3 years) after orthotopic HTx was evaluated. In a first step, a detailed overview of the patients’ somatic condition was assessed. Secondly, patients were compared to 58 control subjects in terms of self‐reported QoL (SF‐36) and psychological domains (GBB‐24; HADS). Finally, a cluster analysis was conducted to identify patterns within the patient‐reported outcome measures (PROMs) and to relate them to somatic, psychosocial, and demographic variables.Results95.7% of the HTx‐patients were in NYHA functional class I or II, and only 15.2% had a reduced LVEF. Compared to controls, long‐term HTx patients had significantly lower scores on the physical component summary (PCS) of QoL and on the GBB‐24 but not in the mental component summary (MCS) of QoL, or anxiety and depression (HADS). Clustering revealed two distinct groups of patients characterized by high versus low functioning and different levels of social support.ConclusionsLong‐term survivors have a good functional, cardiac, and mental status, but report a lower physical QoL and higher levels of subjective complaints. The importance of social support for HTx recipients is once again highlighted. 10.1111/ctr.15400 http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| title | Quality of Life in Patients 20–31 Years After Heart Transplantation |
| topic | Clinical Transplantation |
| url | https://onlinelibrary.wiley.com/doi/10.1111/ctr.15400 |