Mechanical Circulatory Support for Right Ventricular Primary Graft Dysfunction After Heart Transplant: A Review

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Hauptverfasser: Einar A. Hart, S. A. Braithwaite, J. A. J. Hermens, A. O. Kraaijeveld, F. Ramjankhan, L. W. van Laake, M. I. F. J. Oerlemans, M. K. Szymanski
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Veröffentlicht: Wiley 2024
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author Einar A. Hart
S. A. Braithwaite
J. A. J. Hermens
A. O. Kraaijeveld
F. Ramjankhan
L. W. van Laake
M. I. F. J. Oerlemans
M. K. Szymanski
author_facet Einar A. Hart
S. A. Braithwaite
J. A. J. Hermens
A. O. Kraaijeveld
F. Ramjankhan
L. W. van Laake
M. I. F. J. Oerlemans
M. K. Szymanski
Einar A. Hart
S. A. Braithwaite
J. A. J. Hermens
A. O. Kraaijeveld
F. Ramjankhan
L. W. van Laake
M. I. F. J. Oerlemans
M. K. Szymanski
collection Wiley Open Access
contents Mechanical Circulatory Support for Right Ventricular Primary Graft Dysfunction After Heart Transplant: A Review Einar A. Hart S. A. Braithwaite J. A. J. Hermens A. O. Kraaijeveld F. Ramjankhan L. W. van Laake M. I. F. J. Oerlemans M. K. Szymanski Clinical Transplantation ABSTRACTPrimary graft dysfunction (PGD) is the most common cause of early mortality following heart transplantation. Although PGD can affect both ventricles, isolated right ventricular dysfunction (RV‐PGD) is observed in nearly half of PGD patients. RV‐PGD requires specific medical management to support the preload, afterload, and function of the failing RV; however, the use of mechanical circulatory support of the RV (RV‐MCS) might be required when optimal medical therapy is insufficient in preventing forward failure and retrograde venous congestion. While RV‐MCS options provide the opportunity to prevent or to recover from circulatory shock states, MCS is associated with a significant risk of complications. As a result of recent developments in short‐term mechanical support devices, less invasive, percutaneous options for RV‐MCS are available. In this review, we discuss the available devices, their advantages and disadvantages, and reported outcomes in RV‐PGD. 10.1111/ctr.70066 http://creativecommons.org/licenses/by-nc/4.0/
doi_str_mv 10.1111/ctr.70066
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publisher Wiley
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spellingShingle Mechanical Circulatory Support for Right Ventricular Primary Graft Dysfunction After Heart Transplant: A Review
Einar A. Hart
S. A. Braithwaite
J. A. J. Hermens
A. O. Kraaijeveld
F. Ramjankhan
L. W. van Laake
M. I. F. J. Oerlemans
M. K. Szymanski
Clinical Transplantation
Mechanical Circulatory Support for Right Ventricular Primary Graft Dysfunction After Heart Transplant: A Review Einar A. Hart S. A. Braithwaite J. A. J. Hermens A. O. Kraaijeveld F. Ramjankhan L. W. van Laake M. I. F. J. Oerlemans M. K. Szymanski Clinical Transplantation ABSTRACTPrimary graft dysfunction (PGD) is the most common cause of early mortality following heart transplantation. Although PGD can affect both ventricles, isolated right ventricular dysfunction (RV‐PGD) is observed in nearly half of PGD patients. RV‐PGD requires specific medical management to support the preload, afterload, and function of the failing RV; however, the use of mechanical circulatory support of the RV (RV‐MCS) might be required when optimal medical therapy is insufficient in preventing forward failure and retrograde venous congestion. While RV‐MCS options provide the opportunity to prevent or to recover from circulatory shock states, MCS is associated with a significant risk of complications. As a result of recent developments in short‐term mechanical support devices, less invasive, percutaneous options for RV‐MCS are available. In this review, we discuss the available devices, their advantages and disadvantages, and reported outcomes in RV‐PGD. 10.1111/ctr.70066 http://creativecommons.org/licenses/by-nc/4.0/
title Mechanical Circulatory Support for Right Ventricular Primary Graft Dysfunction After Heart Transplant: A Review
topic Clinical Transplantation
url https://onlinelibrary.wiley.com/doi/10.1111/ctr.70066