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Main Authors: David Rekhtman, Amit Iyengar, Cindy Song, Michaela Asher, Max Shin, Michael Catalano, Omar Toubat, Emma Morganroth, Alyson Brown, Joyce Wald, Aditya Parikh, Mauer Biscotti, Marisa Cevasco
Format: Artículo Open Access
Published: Wiley 2026
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Online Access:https://onlinelibrary.wiley.com/doi/10.1111/ctr.70452
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author David Rekhtman
Amit Iyengar
Cindy Song
Michaela Asher
Max Shin
Michael Catalano
Omar Toubat
Emma Morganroth
Alyson Brown
Joyce Wald
Aditya Parikh
Mauer Biscotti
Marisa Cevasco
author_facet David Rekhtman
Amit Iyengar
Cindy Song
Michaela Asher
Max Shin
Michael Catalano
Omar Toubat
Emma Morganroth
Alyson Brown
Joyce Wald
Aditya Parikh
Mauer Biscotti
Marisa Cevasco
David Rekhtman
Amit Iyengar
Cindy Song
Michaela Asher
Max Shin
Michael Catalano
Omar Toubat
Emma Morganroth
Alyson Brown
Joyce Wald
Aditya Parikh
Mauer Biscotti
Marisa Cevasco
collection Wiley Open Access
contents Impact of Prolonged Impella 5.5 Support on Post‐Transplant Outcomes: An Institutional Study David Rekhtman Amit Iyengar Cindy Song Michaela Asher Max Shin Michael Catalano Omar Toubat Emma Morganroth Alyson Brown Joyce Wald Aditya Parikh Mauer Biscotti Marisa Cevasco Clinical Transplantation ABSTRACT Objectives Microaxial flow pump devices are utilized as a bridge to heart transplantation for patients in advanced cardiogenic shock. Little is known about the impact of device duration on post‐transplant outcomes. This study aims to compare post‐transplantation outcomes based on duration of support with the Impella 5.5. Methods All patients who were successfully bridged to transplant on the Impella 5.5 platform were included and stratified based on support duration (≤ 14 days vs. > 14 days). Baseline clinical characteristics were collected throughout the index admission. Outcomes included 1‐year mortality, complications during the index admission, graft rejection, and rehospitalization within the first year. Results Of the 72 patients successfully bridged to transplant, 64% (n = 46) were supported for more than 14 days. When stratified by duration of Impella 5.5 use, there were no differences in pretransplantation clinical status. Length of stay (26 vs. 20 days, p = 0.316) and rates of home discharges (65% vs. 67%, p = 0.524) were similar. Despite a high prevalence of rehospitalization at 1 year (75%), the 1‐year survival was 96% and similar between the two cohorts ( p = 0.289). Conclusions Use of a prolonged microaxial flow pump may be a safe bridging strategy for heart transplantation given comparable post‐transplant outcomes for patients stratified by support duration. 10.1111/ctr.70452 http://creativecommons.org/licenses/by/4.0/
doi_str_mv 10.1111/ctr.70452
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institution Wiley Open Access
license_str_mv http://creativecommons.org/licenses/by/4.0/
publishDate 2026
publisher Wiley
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spellingShingle Impact of Prolonged Impella 5.5 Support on Post‐Transplant Outcomes: An Institutional Study
David Rekhtman
Amit Iyengar
Cindy Song
Michaela Asher
Max Shin
Michael Catalano
Omar Toubat
Emma Morganroth
Alyson Brown
Joyce Wald
Aditya Parikh
Mauer Biscotti
Marisa Cevasco
Clinical Transplantation
Impact of Prolonged Impella 5.5 Support on Post‐Transplant Outcomes: An Institutional Study David Rekhtman Amit Iyengar Cindy Song Michaela Asher Max Shin Michael Catalano Omar Toubat Emma Morganroth Alyson Brown Joyce Wald Aditya Parikh Mauer Biscotti Marisa Cevasco Clinical Transplantation ABSTRACT Objectives Microaxial flow pump devices are utilized as a bridge to heart transplantation for patients in advanced cardiogenic shock. Little is known about the impact of device duration on post‐transplant outcomes. This study aims to compare post‐transplantation outcomes based on duration of support with the Impella 5.5. Methods All patients who were successfully bridged to transplant on the Impella 5.5 platform were included and stratified based on support duration (≤ 14 days vs. > 14 days). Baseline clinical characteristics were collected throughout the index admission. Outcomes included 1‐year mortality, complications during the index admission, graft rejection, and rehospitalization within the first year. Results Of the 72 patients successfully bridged to transplant, 64% (n = 46) were supported for more than 14 days. When stratified by duration of Impella 5.5 use, there were no differences in pretransplantation clinical status. Length of stay (26 vs. 20 days, p = 0.316) and rates of home discharges (65% vs. 67%, p = 0.524) were similar. Despite a high prevalence of rehospitalization at 1 year (75%), the 1‐year survival was 96% and similar between the two cohorts ( p = 0.289). Conclusions Use of a prolonged microaxial flow pump may be a safe bridging strategy for heart transplantation given comparable post‐transplant outcomes for patients stratified by support duration. 10.1111/ctr.70452 http://creativecommons.org/licenses/by/4.0/
title Impact of Prolonged Impella 5.5 Support on Post‐Transplant Outcomes: An Institutional Study
topic Clinical Transplantation
url https://onlinelibrary.wiley.com/doi/10.1111/ctr.70452