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| Format: | Artículo Open Access |
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Wiley
2026
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| Online Access: | https://onlinelibrary.wiley.com/doi/10.1111/ctr.70554 |
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| author | Ronit Patnaik Jillian Woodworth Byeong Yeob Choi Roman Fernandez J. Michael Cullen Eugenia Tsai Francisco Cigarroa Tarunjeet Klair |
| author_facet | Ronit Patnaik Jillian Woodworth Byeong Yeob Choi Roman Fernandez J. Michael Cullen Eugenia Tsai Francisco Cigarroa Tarunjeet Klair Ronit Patnaik Jillian Woodworth Byeong Yeob Choi Roman Fernandez J. Michael Cullen Eugenia Tsai Francisco Cigarroa Tarunjeet Klair |
| collection | Wiley Open Access |
| contents | Addressing Racial Disparities in a Hispanic Population Through Living Donor Liver Transplantation—A Comparison of 2 Eras Ronit Patnaik Jillian Woodworth Byeong Yeob Choi Roman Fernandez J. Michael Cullen Eugenia Tsai Francisco Cigarroa Tarunjeet Klair Clinical Transplantation Abstract Introduction: Hispanic patients experience lower rates of liver transplant referral and living donation compared to non‐Hispanic white (NHW) patients, often due to socioeconomic barriers. This study evaluated the impact of initiating a living donor liver transplant (LDLT) program on waitlist outcomes and ethnic disparities at a single center. Methods: A retrospective analysis compared Hispanic and NHW waitlist outcomes between two eras: before (Era 1: 2012–2017) and after (Era 2: 2018–2024) LDLT program implementation. Outcomes included LDLT, deceased donor liver transplant (DDLT), death or clinical deterioration (DOD), and clinical improvement. Sub‐distribution hazard models and Kaplan‐Meier survival analyses were used. Results: 1156 liver transplants were performed in Hispanic and NHW patients. Era 2 patients experienced significantly shorter waitlist times (236 vs. 365 days, p <0.001). NHW patients were more likely to have higher education, be English‐speaking U.S. citizens, and be employed. Hispanic LDLT recipients more often had biologic donors. LDLT likelihood increased significantly in Era 2 (HR = 5.77, p <0.001), while waitlist DOD rates decreased by 48% (HR = 0.52, p <0.001). NHW patients had a higher chance of LDLT (HR = 1.67, p <0.001) and lower DOD risk (HR = 0.70, p = 0.001) than Hispanic patients, although DOD decreased for both groups. Women had a higher rate of LDLT (HR = 1.58) but also higher DOD (HR = 1.26). In Era 1, Hispanic LDLT recipients had worse post‐transplant survival, but outcomes improved to match NHW recipients in Era 2 ( p = 0.88). Conclusion Implementation of a LDLT program improved access and waitlist outcomes for all groups, especially Hispanic, despite significant socioeconomic barriers, and female patients. 10.1111/ctr.70554 http://onlinelibrary.wiley.com/termsAndConditions#vor |
| doi_str_mv | 10.1111/ctr.70554 |
| format | Artículo Open Access |
| id | wiley_oa_10_1111_ctr_70554 |
| institution | Wiley Open Access |
| license_str_mv | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| publishDate | 2026 |
| publisher | Wiley |
| record_format | wiley_oa |
| spellingShingle | Addressing Racial Disparities in a Hispanic Population Through Living Donor Liver Transplantation—A Comparison of 2 Eras Ronit Patnaik Jillian Woodworth Byeong Yeob Choi Roman Fernandez J. Michael Cullen Eugenia Tsai Francisco Cigarroa Tarunjeet Klair Clinical Transplantation Addressing Racial Disparities in a Hispanic Population Through Living Donor Liver Transplantation—A Comparison of 2 Eras Ronit Patnaik Jillian Woodworth Byeong Yeob Choi Roman Fernandez J. Michael Cullen Eugenia Tsai Francisco Cigarroa Tarunjeet Klair Clinical Transplantation Abstract Introduction: Hispanic patients experience lower rates of liver transplant referral and living donation compared to non‐Hispanic white (NHW) patients, often due to socioeconomic barriers. This study evaluated the impact of initiating a living donor liver transplant (LDLT) program on waitlist outcomes and ethnic disparities at a single center. Methods: A retrospective analysis compared Hispanic and NHW waitlist outcomes between two eras: before (Era 1: 2012–2017) and after (Era 2: 2018–2024) LDLT program implementation. Outcomes included LDLT, deceased donor liver transplant (DDLT), death or clinical deterioration (DOD), and clinical improvement. Sub‐distribution hazard models and Kaplan‐Meier survival analyses were used. Results: 1156 liver transplants were performed in Hispanic and NHW patients. Era 2 patients experienced significantly shorter waitlist times (236 vs. 365 days, p <0.001). NHW patients were more likely to have higher education, be English‐speaking U.S. citizens, and be employed. Hispanic LDLT recipients more often had biologic donors. LDLT likelihood increased significantly in Era 2 (HR = 5.77, p <0.001), while waitlist DOD rates decreased by 48% (HR = 0.52, p <0.001). NHW patients had a higher chance of LDLT (HR = 1.67, p <0.001) and lower DOD risk (HR = 0.70, p = 0.001) than Hispanic patients, although DOD decreased for both groups. Women had a higher rate of LDLT (HR = 1.58) but also higher DOD (HR = 1.26). In Era 1, Hispanic LDLT recipients had worse post‐transplant survival, but outcomes improved to match NHW recipients in Era 2 ( p = 0.88). Conclusion Implementation of a LDLT program improved access and waitlist outcomes for all groups, especially Hispanic, despite significant socioeconomic barriers, and female patients. 10.1111/ctr.70554 http://onlinelibrary.wiley.com/termsAndConditions#vor |
| title | Addressing Racial Disparities in a Hispanic Population Through Living Donor Liver Transplantation—A Comparison of 2 Eras |
| topic | Clinical Transplantation |
| url | https://onlinelibrary.wiley.com/doi/10.1111/ctr.70554 |