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| Main Authors: | , , , , , , , |
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| Format: | Artículo Open Access |
| Published: |
Wiley
2026
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| Online Access: | https://onlinelibrary.wiley.com/doi/10.1111/ctr.70554 |
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Table of Contents:
- Addressing Racial Disparities in a Hispanic Population Through Living Donor Liver Transplantation—A Comparison of 2 Eras Ronit Patnaik Jillian Woodworth Byeong Yeob Choi Roman Fernandez J. Michael Cullen Eugenia Tsai Francisco Cigarroa Tarunjeet Klair Clinical Transplantation Abstract Introduction: Hispanic patients experience lower rates of liver transplant referral and living donation compared to non‐Hispanic white (NHW) patients, often due to socioeconomic barriers. This study evaluated the impact of initiating a living donor liver transplant (LDLT) program on waitlist outcomes and ethnic disparities at a single center. Methods: A retrospective analysis compared Hispanic and NHW waitlist outcomes between two eras: before (Era 1: 2012–2017) and after (Era 2: 2018–2024) LDLT program implementation. Outcomes included LDLT, deceased donor liver transplant (DDLT), death or clinical deterioration (DOD), and clinical improvement. Sub‐distribution hazard models and Kaplan‐Meier survival analyses were used. Results: 1156 liver transplants were performed in Hispanic and NHW patients. Era 2 patients experienced significantly shorter waitlist times (236 vs. 365 days, p <0.001). NHW patients were more likely to have higher education, be English‐speaking U.S. citizens, and be employed. Hispanic LDLT recipients more often had biologic donors. LDLT likelihood increased significantly in Era 2 (HR = 5.77, p <0.001), while waitlist DOD rates decreased by 48% (HR = 0.52, p <0.001). NHW patients had a higher chance of LDLT (HR = 1.67, p <0.001) and lower DOD risk (HR = 0.70, p = 0.001) than Hispanic patients, although DOD decreased for both groups. Women had a higher rate of LDLT (HR = 1.58) but also higher DOD (HR = 1.26). In Era 1, Hispanic LDLT recipients had worse post‐transplant survival, but outcomes improved to match NHW recipients in Era 2 ( p = 0.88). Conclusion Implementation of a LDLT program improved access and waitlist outcomes for all groups, especially Hispanic, despite significant socioeconomic barriers, and female patients. 10.1111/ctr.70554 http://onlinelibrary.wiley.com/termsAndConditions#vor