Evaluating the impact of severe hypoglycaemia definition wording on severe hypoglycaemia history assessment
Fuente:
Wiley Open Access
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Artículo Open Access |
| Published: |
Wiley
2025
|
| Subjects: | |
| Online Access: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1867010352484450304 |
|---|---|
| author | Yu Kuei Lin Wen Ye Emily Hepworth Lynn Ang Stephanie A. Amiel Simon J. Fisher |
| author_facet | Yu Kuei Lin Wen Ye Emily Hepworth Lynn Ang Stephanie A. Amiel Simon J. Fisher Yu Kuei Lin Wen Ye Emily Hepworth Lynn Ang Stephanie A. Amiel Simon J. Fisher |
| collection | Wiley Open Access |
| contents | Evaluating the impact of severe hypoglycaemia definition wording on severe hypoglycaemia history assessment Yu Kuei Lin Wen Ye Emily Hepworth Lynn Ang Stephanie A. Amiel Simon J. Fisher Diabetic Medicine AbstractAimSeveral wordings of the definition of severe hypoglycaemia (SH) exist. This study aims to evaluate how different SH definition wordings affect SH history assessment.MethodsIn this cross‐sectional study, surveys were emailed to registrants of the T1D Exchange, a U.S. national type 1 diabetes patient registry. Participants' demographic information was collected. Six‐month SH history was evaluated with questionnaires including SH definition wordings from either (1) professional societies, (2) a diabetes community website, or (3) a hypoglycaemia research questionnaire. Analyses included the McNemar test, pairwise Wilcoxon signed‐rank test, logistic regression analysis, Kappa statistics, and Spearman correlation.ResultsA total of 1580 valid responses were obtained from participants (52% female; mean ± SD age: 46 ± 15 years; 95% White; mean ± SD diabetes duration: 25 ± 16 years). Questionnaires with four different SH definition wordings yielded significant variations in the prevalence of SH (i.e., having developed at least one episode of SH) and the number of SH episodes: the ADA/ENDO 2013 definition wording yielded the highest results on both metrics, whereas HypoA‐Q and ADA 2023 yielded the lowest. Among participants reporting at least one SH episode, the number of episodes identified with the different SH definition wordings was poorly correlated (Rs: 0.09–0.37; p < 0.001). Race, education level, and household income were associated with higher odds of discrepancies in SH history (p < 0.05).ConclusionThis U.S. national survey with individuals living with type 1 diabetes demonstrated significant discrepancies in SH history when assessed with different SH definition wordings. Race and socioeconomic status were associated with these discrepancies. 10.1111/dme.15513 http://creativecommons.org/licenses/by-nc/4.0/ |
| doi_str_mv | 10.1111/dme.15513 |
| format | Artículo Open Access |
| id | wiley_oa_10_1111_dme_15513 |
| institution | Wiley Open Access |
| license_str_mv | http://creativecommons.org/licenses/by-nc/4.0/ |
| publishDate | 2025 |
| publisher | Wiley |
| record_format | wiley_oa |
| spellingShingle | Evaluating the impact of severe hypoglycaemia definition wording on severe hypoglycaemia history assessment Yu Kuei Lin Wen Ye Emily Hepworth Lynn Ang Stephanie A. Amiel Simon J. Fisher Diabetic Medicine Evaluating the impact of severe hypoglycaemia definition wording on severe hypoglycaemia history assessment Yu Kuei Lin Wen Ye Emily Hepworth Lynn Ang Stephanie A. Amiel Simon J. Fisher Diabetic Medicine AbstractAimSeveral wordings of the definition of severe hypoglycaemia (SH) exist. This study aims to evaluate how different SH definition wordings affect SH history assessment.MethodsIn this cross‐sectional study, surveys were emailed to registrants of the T1D Exchange, a U.S. national type 1 diabetes patient registry. Participants' demographic information was collected. Six‐month SH history was evaluated with questionnaires including SH definition wordings from either (1) professional societies, (2) a diabetes community website, or (3) a hypoglycaemia research questionnaire. Analyses included the McNemar test, pairwise Wilcoxon signed‐rank test, logistic regression analysis, Kappa statistics, and Spearman correlation.ResultsA total of 1580 valid responses were obtained from participants (52% female; mean ± SD age: 46 ± 15 years; 95% White; mean ± SD diabetes duration: 25 ± 16 years). Questionnaires with four different SH definition wordings yielded significant variations in the prevalence of SH (i.e., having developed at least one episode of SH) and the number of SH episodes: the ADA/ENDO 2013 definition wording yielded the highest results on both metrics, whereas HypoA‐Q and ADA 2023 yielded the lowest. Among participants reporting at least one SH episode, the number of episodes identified with the different SH definition wordings was poorly correlated (Rs: 0.09–0.37; p < 0.001). Race, education level, and household income were associated with higher odds of discrepancies in SH history (p < 0.05).ConclusionThis U.S. national survey with individuals living with type 1 diabetes demonstrated significant discrepancies in SH history when assessed with different SH definition wordings. Race and socioeconomic status were associated with these discrepancies. 10.1111/dme.15513 http://creativecommons.org/licenses/by-nc/4.0/ |
| title | Evaluating the impact of severe hypoglycaemia definition wording on severe hypoglycaemia history assessment |
| topic | Diabetic Medicine |
| url | https://onlinelibrary.wiley.com/doi/10.1111/dme.15513 |